Holzbaur ELF - Search Results

1

The selective autophagy adaptor p62/SQSTM1 forms phase condensates regulated by HSP27 that facilitate the clearance of damaged lysosomes via lysophagy.

Gallagher ER, Holzbaur ELF. Gallagher ER, et al. Among authors: holzbaur elf. Cell Rep. 2023 Feb 28;42(2):112037. doi: 10.1016/j.celrep.2023.112037. Epub 2023 Jan 25. Cell Rep. 2023. PMID: 36701233 Free PMC article.

2

Stress-Induced CDK5 Activation Disrupts Axonal Transport via Lis1/Ndel1/Dynein.

Klinman E, Holzbaur EL. Klinman E, et al. Cell Rep. 2015 Jul 21;12(3):462-73. doi: 10.1016/j.celrep.2015.06.032. Epub 2015 Jul 9. Cell Rep. 2015. PMID: 26166569 Free PMC article.

3

α-Tubulin Tyrosination and CLIP-170 Phosphorylation Regulate the Initiation of Dynein-Driven Transport in Neurons.

Nirschl JJ, Magiera MM, Lazarus JE, Janke C, Holzbaur EL. Nirschl JJ, et al. Cell Rep. 2016 Mar 22;14(11):2637-52. doi: 10.1016/j.celrep.2016.02.046. Epub 2016 Mar 10. Cell Rep. 2016. PMID: 26972003 Free PMC article.

4

Autophagy in Neurons.

Stavoe AKH, Holzbaur ELF. Stavoe AKH, et al. Among authors: holzbaur elf. Annu Rev Cell Dev Biol. 2019 Oct 6;35:477-500. doi: 10.1146/annurev-cellbio-100818-125242. Epub 2019 Jul 23. Annu Rev Cell Dev Biol. 2019. PMID: 31340124 Free PMC article. Review.

5

ToolBox: Live Imaging of intracellular organelle transport in induced pluripotent stem cell-derived neurons.

Boecker CA, Olenick MA, Gallagher ER, Ward ME, Holzbaur ELF. Boecker CA, et al. Among authors: holzbaur elf. Traffic. 2020 Jan;21(1):138-155. doi: 10.1111/tra.12701. Epub 2019 Nov 15. Traffic. 2020. PMID: 31603614 Free PMC article.

6

NIX initiates mitochondrial fragmentation via DRP1 to drive epidermal differentiation.

Simpson CL, Tokito MK, Uppala R, Sarkar MK, Gudjonsson JE, Holzbaur ELF. Simpson CL, et al. Among authors: holzbaur elf. Cell Rep. 2021 Feb 2;34(5):108689. doi: 10.1016/j.celrep.2021.108689. Cell Rep. 2021. PMID: 33535046 Free PMC article.

7

ALS-associated KIF5A mutations abolish autoinhibition resulting in a toxic gain of function.

Baron DM, Fenton AR, Saez-Atienzar S, Giampetruzzi A, Sreeram A, Shankaracharya, Keagle PJ, Doocy VR, Smith NJ, Danielson EW, Andresano M, McCormack MC, Garcia J, Bercier V, Van Den Bosch L, Brent JR, Fallini C, Traynor BJ, Holzbaur ELF, Landers JE. Baron DM, et al. Among authors: holzbaur elf. Cell Rep. 2022 Apr 5;39(1):110598. doi: 10.1016/j.celrep.2022.110598. Cell Rep. 2022. PMID: 35385738 Free PMC article.

8

Regulatory imbalance between LRRK2 kinase, PPM1H phosphatase, and ARF6 GTPase disrupts the axonal transport of autophagosomes.

Dou D, Smith EM, Evans CS, Boecker CA, Holzbaur ELF. Dou D, et al. Among authors: holzbaur elf. Cell Rep. 2023 May 30;42(5):112448. doi: 10.1016/j.celrep.2023.112448. Epub 2023 May 1. Cell Rep. 2023. PMID: 37133994 Free PMC article.

9

SQSTM1/P62 promotes lysophagy via formation of liquid-like condensates maintained by HSP27.

Gallagher ER, Holzbaur ELF. Gallagher ER, et al. Among authors: holzbaur elf. Autophagy. 2023 Nov;19(11):3029-3030. doi: 10.1080/15548627.2023.2210943. Epub 2023 May 16. Autophagy. 2023. PMID: 37194327 Free PMC article.

10

Damaged mitochondria recruit the effector NEMO to activate NF-κB signaling.

Harding O, Holzer E, Riley JF, Martens S, Holzbaur ELF. Harding O, et al. Among authors: holzbaur elf. Mol Cell. 2023 Sep 7;83(17):3188-3204.e7. doi: 10.1016/j.molcel.2023.08.005. Mol Cell. 2023. PMID: 37683611 Free PMC article.

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