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Page 1
Genomic and transcriptomic analyses identify a prognostic gene signature and predict response to therapy in pleural and peritoneal mesothelioma.
Nair NU, Jiang Q, Wei JS, Misra VA, Morrow B, Kesserwan C, Hermida LC, Lee JS, Mian I, Zhang J, Lebensohn A, Miettinen M, Sengupta M, Khan J, Ruppin E, Hassan R. Nair NU, et al. Among authors: ruppin e. Cell Rep Med. 2023 Feb 21;4(2):100938. doi: 10.1016/j.xcrm.2023.100938. Epub 2023 Feb 10. Cell Rep Med. 2023. PMID: 36773602 Free PMC article.
Clinically oriented prediction of patient response to targeted and immunotherapies from the tumor transcriptome.
Dinstag G, Shulman ED, Elis E, Ben-Zvi DS, Tirosh O, Maimon E, Meilijson I, Elalouf E, Temkin B, Vitkovsky P, Schiff E, Hoang DT, Sinha S, Nair NU, Lee JS, Schäffer AA, Ronai Z, Juric D, Apolo AB, Dahut WL, Lipkowitz S, Berger R, Kurzrock R, Papanicolau-Sengos A, Karzai F, Gilbert MR, Aldape K, Rajagopal PS, Beker T, Ruppin E, Aharonov R. Dinstag G, et al. Among authors: ruppin e. Med. 2023 Jan 13;4(1):15-30.e8. doi: 10.1016/j.medj.2022.11.001. Epub 2022 Dec 12. Med. 2023. PMID: 36513065 Free PMC article.
Medication effects on the gut microbiome in allo-HCT.
Robinson W, Gertz EM, Greten TF, Ruppin E. Robinson W, et al. Among authors: ruppin e. Cell. 2023 Jun 8;186(12):2520-2523. doi: 10.1016/j.cell.2023.04.011. Epub 2023 Jun 8. Cell. 2023. PMID: 37295398 Free article.
Increased interleukin-6/C-reactive protein levels are associated with the upregulation of the adenosine pathway and serve as potential markers of therapeutic resistance to immune checkpoint inhibitor-based therapies in non-small cell lung cancer.
Naqash AR, McCallen JD, Mi E, Iivanainen S, Marie MA, Gramenitskaya D, Clark J, Koivunen JP, Macherla S, Jonnalagadda S, Polsani S, Jiwani RA, Hafiz M, Muzaffar M, Brunetti L, Stroud CRG, Walker PR, Wang K, Chung Y, Ruppin E, Lee SH, Yang LV, Pinato DJ, Lee JS, Cortellini A. Naqash AR, et al. Among authors: ruppin e. J Immunother Cancer. 2023 Oct;11(10):e007310. doi: 10.1136/jitc-2023-007310. J Immunother Cancer. 2023. PMID: 37852738 Free PMC article.
Identification of targetable vulnerabilities of PLK1-overexpressing cancers by synthetic dosage lethality.
Cunningham CE, Vizeacoumar FS, Zhang Y, Kyrylenko L, Both S, Maranda V, Dong H, Price JDW, Gao P, Wagner K, Wu Y, Lazell-Wright M, Ganapathysamy A, Hari R, Bhanumathy KK, Denomy C, Saxena A, Vizeacoumar JP, Morales AM, Khan F, Mosley S, Chen A, Katrii T, Zoller BGE, Rajamanickam K, Walke P, Gong L, Patel H, Elhasasna H, Dahiya R, Abuhussein O, Dmitriev A, Freywald T, Munhoz EP, Ruppin E, Lee JS, Rox K, Koebel M, Hopkins L, Lee CH, Yadav S, Gasparoni G, Walter J, Krishnan A, Datla R, Toosi B, Baker K, Meens J, Cescon DW, Ailles L, Leary SC, Wu Y, Empting M, Kiemer AK, Freywald A, Vizeacoumar FJ. Cunningham CE, et al. Among authors: ruppin e. Cell Genom. 2025 Jun 11;5(6):100876. doi: 10.1016/j.xgen.2025.100876. Epub 2025 May 9. Cell Genom. 2025. PMID: 40347943 Free article.
Biomarkers for immunotherapy of hepatocellular carcinoma.
Greten TF, Villanueva A, Korangy F, Ruf B, Yarchoan M, Ma L, Ruppin E, Wang XW. Greten TF, et al. Among authors: ruppin e. Nat Rev Clin Oncol. 2023 Nov;20(11):780-798. doi: 10.1038/s41571-023-00816-4. Epub 2023 Sep 19. Nat Rev Clin Oncol. 2023. PMID: 37726418 Review.
Translation dysregulation in cancer as a source for targetable antigens.
Weller C, Bartok O, McGinnis CS, Palashati H, Chang TG, Malko D, Shmueli MD, Nagao A, Hayoun D, Murayama A, Sakaguchi Y, Poulis P, Khatib A, Erlanger Avigdor B, Gordon S, Cohen Shvefel S, Zemanek MJ, Nielsen MM, Boura-Halfon S, Sagie S, Gumpert N, Yang W, Alexeev D, Kyriakidou P, Yao W, Zerbib M, Greenberg P, Benedek G, Litchfield K, Petrovich-Kopitman E, Nagler A, Oren R, Ben-Dor S, Levin Y, Pilpel Y, Rodnina M, Cox J, Merbl Y, Satpathy AT, Carmi Y, Erhard F, Suzuki T, Buskirk AR, Olweus J, Ruppin E, Schlosser A, Samuels Y. Weller C, et al. Among authors: ruppin e. Cancer Cell. 2025 May 12;43(5):823-840.e18. doi: 10.1016/j.ccell.2025.03.003. Epub 2025 Mar 27. Cancer Cell. 2025. PMID: 40154482 Free article.
373 results