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Page 1
Type 2 inflammation drives an airway basal stem cell program through insulin receptor substrate signaling.
Wang X, Hallen NR, Lee M, Samuchiwal S, Ye Q, Buchheit KM, Maxfield AZ, Roditi RE, Bergmark RW, Bhattacharyya N, Ryan T, Gakpo D, Raychaudhuri S, Dwyer D, Laidlaw TM, Boyce JA, Gutierrez-Arcelus M, Barrett NA. Wang X, et al. J Allergy Clin Immunol. 2023 Jun;151(6):1536-1549. doi: 10.1016/j.jaci.2023.01.030. Epub 2023 Feb 17. J Allergy Clin Immunol. 2023. PMID: 36804595 Free PMC article.
Identical repeated backbone of the human genome.
Zepeda-Mendoza CJ, Lemus T, Yáñez O, García D, Valle-García D, Meza-Sosa KF, Gutiérrez-Arcelus M, Márquez-Ortiz Y, Domínguez-Vidaña R, Gonzaga-Jauregui C, Flores M, Palacios R. Zepeda-Mendoza CJ, et al. BMC Genomics. 2010 Jan 23;11:60. doi: 10.1186/1471-2164-11-60. BMC Genomics. 2010. PMID: 20096123 Free PMC article.
High-throughput identification of functional regulatory SNPs in systemic lupus erythematosus.
Nigrovic PA, Wang Q, Kim T, Martinez-Bonet M, Aguiar VRC, Sim S, Cui J, Sparks JA, Chen X, Todd M, Wauford B, Marion MC, Langefeld CD, Weirauch MT, Gutierrez-Arcelus M. Nigrovic PA, et al. bioRxiv [Preprint]. 2024 Apr 12:2023.08.16.553538. doi: 10.1101/2023.08.16.553538. bioRxiv. 2024. Update in: Nat Commun. 2024 Aug 9;15(1):6804. doi: 10.1038/s41467-024-50710-5. PMID: 37645953 Free PMC article. Updated. Preprint.
A multi-omics resource of B cell activation reveals genetic mechanisms for immune-mediated diseases.
Aguiar VRC, Franco ME, Aziz NA, Fernandez-Salinas D, Chiñas M, Colantuoni M, Xiao Q, Hackert N, Liao Y, Cervantes-Diaz R, Todd M, Wauford B, Wactor A, Prahalad V, Laza-Briviesca R, Darbousset R, Wang Q, Jenks S, Cashman KS, Zumaquero E, Zhu Z, Case J, Cejas P, Gomez M, Ainsworth H, Marion M, Benamar M, Lee P, Henderson L, Chang M, Wei K, Long H, Langefeld CD, Gewurz BE, Sanz I, Sparks JA, Meidan E, Nigrovic PA, Gutierrez-Arcelus M. Aguiar VRC, et al. Among authors: gutierrez arcelus m. medRxiv [Preprint]. 2025 Jun 14:2025.05.22.25328104. doi: 10.1101/2025.05.22.25328104. medRxiv. 2025. PMID: 40475139 Free PMC article. Preprint.
Evolutionary genetics of the human Rh blood group system.
Perry GH, Xue Y, Smith RS, Meyer WK, Calışkan M, Yanez-Cuna O, Lee AS, Gutiérrez-Arcelus M, Ober C, Hollox EJ, Tyler-Smith C, Lee C. Perry GH, et al. Hum Genet. 2012 Jul;131(7):1205-16. doi: 10.1007/s00439-012-1147-5. Epub 2012 Feb 25. Hum Genet. 2012. PMID: 22367406 Free PMC article.
Discovering in vivo cytokine-eQTL interactions from a lupus clinical trial.
Davenport EE, Amariuta T, Gutierrez-Arcelus M, Slowikowski K, Westra HJ, Luo Y, Shen C, Rao DA, Zhang Y, Pearson S, von Schack D, Beebe JS, Bing N, John S, Vincent MS, Zhang B, Raychaudhuri S. Davenport EE, et al. Genome Biol. 2018 Oct 19;19(1):168. doi: 10.1186/s13059-018-1560-8. Genome Biol. 2018. PMID: 30340504 Free PMC article. Clinical Trial.
Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry.
Zhang F, Wei K, Slowikowski K, Fonseka CY, Rao DA, Kelly S, Goodman SM, Tabechian D, Hughes LB, Salomon-Escoto K, Watts GFM, Jonsson AH, Rangel-Moreno J, Meednu N, Rozo C, Apruzzese W, Eisenhaure TM, Lieb DJ, Boyle DL, Mandelin AM 2nd; Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Consortium; Boyce BF, DiCarlo E, Gravallese EM, Gregersen PK, Moreland L, Firestein GS, Hacohen N, Nusbaum C, Lederer JA, Perlman H, Pitzalis C, Filer A, Holers VM, Bykerk VP, Donlin LT, Anolik JH, Brenner MB, Raychaudhuri S. Zhang F, et al. Nat Immunol. 2019 Jul;20(7):928-942. doi: 10.1038/s41590-019-0378-1. Epub 2019 May 6. Nat Immunol. 2019. PMID: 31061532 Free PMC article.
77 results