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Page 1
Hypoimmune induced pluripotent stem cells survive long term in fully immunocompetent, allogeneic rhesus macaques.
Hu X, White K, Olroyd AG, DeJesus R, Dominguez AA, Dowdle WE, Friera AM, Young C, Wells F, Chu EY, Ito CE, Krishnapura H, Jain S, Ankala R, McGill TJ, Lin A, Egenberger K, Gagnon A, Michael Rukstalis J, Hogrebe NJ, Gattis C, Basco R, Millman JR, Kievit P, Davis MM, Lanier LL, Connolly AJ, Deuse T, Schrepfer S. Hu X, et al. Among authors: olroyd ag. Nat Biotechnol. 2024 Mar;42(3):413-423. doi: 10.1038/s41587-023-01784-x. Epub 2023 May 8. Nat Biotechnol. 2024. PMID: 37156915 Free PMC article.
Human hypoimmune primary pancreatic islets avoid rejection and autoimmunity and alleviate diabetes in allogeneic humanized mice.
Hu X, Gattis C, Olroyd AG, Friera AM, White K, Young C, Basco R, Lamba M, Wells F, Ankala R, Dowdle WE, Lin A, Egenberger K, Rukstalis JM, Millman JR, Connolly AJ, Deuse T, Schrepfer S. Hu X, et al. Among authors: olroyd ag. Sci Transl Med. 2023 Apr 12;15(691):eadg5794. doi: 10.1126/scitranslmed.adg5794. Epub 2023 Apr 12. Sci Transl Med. 2023. PMID: 37043559