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Page 1
Direct recognition of an intact foreign protein by an αβ T cell receptor.
Almeida CF, Gully BS, Jones CM, Kedzierski L, Gunasinghe SD, Rice MT, Berry R, Gherardin NA, Nguyen TT, Mok YF, Reijneveld JF, Moody DB, Van Rhijn I, La Gruta NL, Uldrich AP, Rossjohn J, Godfrey DI. Almeida CF, et al. Among authors: gunasinghe sd. Nat Commun. 2024 Oct 11;15(1):8816. doi: 10.1038/s41467-024-51897-3. Nat Commun. 2024. PMID: 39394178 Free PMC article.
Atypical sideways recognition of CD1a by autoreactive γδ T cell receptors.
Wegrecki M, Ocampo TA, Gunasinghe SD, von Borstel A, Tin SY, Reijneveld JF, Cao TP, Gully BS, Le Nours J, Moody DB, Van Rhijn I, Rossjohn J. Wegrecki M, et al. Among authors: gunasinghe sd. Nat Commun. 2022 Jul 5;13(1):3872. doi: 10.1038/s41467-022-31443-9. Nat Commun. 2022. PMID: 35790773 Free PMC article.
Structure of a fully assembled γδ T cell antigen receptor.
Gully BS, Ferreira Fernandes J, Gunasinghe SD, Vuong MT, Lui Y, Rice MT, Rashleigh L, Lay CS, Littler DR, Sharma S, Santos AM, Venugopal H, Rossjohn J, Davis SJ. Gully BS, et al. Among authors: gunasinghe sd. Nature. 2024 Oct;634(8034):729-736. doi: 10.1038/s41586-024-07920-0. Epub 2024 Aug 15. Nature. 2024. PMID: 39146975 Free PMC article.
Biomechanics of T Cell Dysfunctions in Chronic Diseases.
Gunasinghe SD, Peres NG, Goyette J, Gaus K. Gunasinghe SD, et al. Front Immunol. 2021 Feb 25;12:600829. doi: 10.3389/fimmu.2021.600829. eCollection 2021. Front Immunol. 2021. PMID: 33717081 Free PMC article. Review.
Canonical T cell receptor docking on peptide-MHC is essential for T cell signaling.
Zareie P, Szeto C, Farenc C, Gunasinghe SD, Kolawole EM, Nguyen A, Blyth C, Sng XYX, Li J, Jones CM, Fulcher AJ, Jacobs JR, Wei Q, Wojciech L, Petersen J, Gascoigne NRJ, Evavold BD, Gaus K, Gras S, Rossjohn J, La Gruta NL. Zareie P, et al. Among authors: gunasinghe sd. Science. 2021 Jun 4;372(6546):eabe9124. doi: 10.1126/science.abe9124. Science. 2021. PMID: 34083463
12 results