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Page 1
Targeting hypoxia-inducible factors with 32-134D safely and effectively treats diabetic eye disease in mice.
Zhang J, Sharma D, Dinabandhu A, Sanchez J, Applewhite B, Jee K, Deshpande M, Flores-Bellver M, Hu MW, Guo C, Salman S, Hwang Y, Anders NM, Rudek MA, Qian J, Canto-Soler MV, Semenza GL, Montaner S, Sodhi A. Zhang J, et al. Among authors: deshpande m. J Clin Invest. 2023 Jul 3;133(13):e163290. doi: 10.1172/JCI163290. J Clin Invest. 2023. PMID: 37227777 Free PMC article.
HIF-1α accumulation in response to transient hypoglycemia may worsen diabetic eye disease.
Guo C, Deshpande M, Niu Y, Kachwala I, Flores-Bellver M, Megarity H, Nuse T, Babapoor-Farrokhran S, Ramada M, Sanchez J, Inamdar N, Johnson TV, Canto-Soler MV, Montaner S, Sodhi A. Guo C, et al. Among authors: deshpande m. Cell Rep. 2023 Jan 31;42(1):111976. doi: 10.1016/j.celrep.2022.111976. Epub 2023 Jan 10. Cell Rep. 2023. PMID: 36640318 Free PMC article.
Pathologic vs. protective roles of hypoxia-inducible factor 1 in RPE and photoreceptors in wet vs. dry age-related macular degeneration.
Babapoor-Farrokhran S, Qin Y, Flores-Bellver M, Niu Y, Bhutto IA, Aparicio-Domingo S, Guo C, Rodrigues M, Domashevich T, Deshpande M, Megarity H, Chopde R, Eberhart CG, Canto-Soler V, Montaner S, Sodhi A. Babapoor-Farrokhran S, et al. Among authors: deshpande m. Proc Natl Acad Sci U S A. 2023 Dec 12;120(50):e2302845120. doi: 10.1073/pnas.2302845120. Epub 2023 Dec 6. Proc Natl Acad Sci U S A. 2023. PMID: 38055741 Free PMC article.
Exploring alkaloids and flavonoids from natural sources: Emerging natural agents for inhibiting cervical cancer progression through apoptosis induction, anti-inflammatory effects, and oxidative stress reduction.
Chen Y, Yu D, Zhu D, Muthusamy S, Deshpande M, Kiruthiga N, Theivendren P, Rajalakshmi K, Wu S, Zhu C. Chen Y, et al. Among authors: deshpande m. Pathol Res Pract. 2025 Jun 24;272:156092. doi: 10.1016/j.prp.2025.156092. Online ahead of print. Pathol Res Pract. 2025. PMID: 40596791 Review.
Discovery and Characterization of a First-in-Class LIV1-TLR7/8 Immunomodulatory Conjugate with Robust Myeloid Activation and Antitumor Activity.
Yamazoe S, Poudel Y, Sega E, Mukhopadhyay A, Ramakrishnan R, Ukairo O, Liu S, Akter R, Sadanala K, Que K, Cheng Q, Kotapati S, Deshpande M, Cox M, Chourey S, Gupta A, Kempson J, Pabbisetty K, Kaspady M, Bhattasali D, Yip S, Wu DR, Pookot D, Li Y, Kozhich A, Drexler D, Carl S, Deyanova E, Smith M, Chan H, West S, Diong SJ, Chang A, Florin L, Mathur A, Strop P, Zapf CW, Law D, Wilson N, Broz M, Chekler EP. Yamazoe S, et al. Among authors: deshpande m. J Med Chem. 2025 Jun 12;68(11):11322-11339. doi: 10.1021/acs.jmedchem.5c00264. Epub 2025 May 24. J Med Chem. 2025. PMID: 40411528 Free PMC article.
Presentation and outcomes of second primary malignancies (SPMs) in locally advanced oral cavity squamous carcinoma (LA-OSCC): Secondary analysis of a phase III randomised control trial (NCT00193843).
Laskar SG, Sood S, Chatterjee A, Sinha S, Sharma S, Chaukar D, Agarwal JP, Gupta T, Budrukkar A, Murthy V, Swain M, Kumar A, Mohanty S, Chaturvedi P, Pai P, Pantvaidya G, Deshmukh A, Nair D, Nair S, Tuljapurkar V, Deshpande M, Joshi A, Noronha V, Prabhash K, Dcruz AK. Laskar SG, et al. Among authors: deshpande m. Radiother Oncol. 2025 May 21;209:110944. doi: 10.1016/j.radonc.2025.110944. Online ahead of print. Radiother Oncol. 2025. PMID: 40409369
Antibody-Drug Conjugates of NLRP3 Agonists: How Overcoming Lysosomal Accumulation Necessitated Noncanonical Linker Attachments.
Riehl PS, Zhang MY, Dhar P, Wang Z, Pan J, Mansfield K, Johnson WL, Zhang Q, Li Y, D'Souza R, Zhang J, Olsen J, Deshpande M, Kotapati S, Hollingsworth SA, Verma I, Li YX, Su Y, Cheng Q, Yamazoe S, Micci L, Broz M, Janc J, Chekler EP, Lo JC. Riehl PS, et al. Among authors: deshpande m. J Med Chem. 2025 May 8;68(9):9799-9810. doi: 10.1021/acs.jmedchem.5c00596. Epub 2025 Apr 29. J Med Chem. 2025. PMID: 40300109
562 results