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282 results

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Page 1
Whole genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles.
Huffman JE, Nicolas J, Hahn J, Heath AS, Raffield LM, Yanek LR, Brody JA, Thibord F, Almasy L, Bartz TM, Bielak LF, Bowler RP, Carrasquilla GD, Chasman DI, Chen MH, Emmert DB, Ghanbari M, Haessle J, Hottenga JJ, Kleber ME, Le NQ, Lee J, Lewis JP, Li-Gao R, Luan J, Malmberg A, Mangino M, Marioni RE, Martinez-Perez A, Pankratz N, Polasek O, Richmond A, Rodriguez BA, Rotter JI, Steri M, Suchon P, Trompet S, Weiss S, Zare M, Auer P, Cho MH, Christofidou P, Davies G, de Geus E, Deleuze JF, Delgado GE, Ekunwe L, Faraday N, Gögele M, Greinacher A, He G, Howard T, Joshi PK, Kilpeläinen TO, Lahti J, Linneberg A, Naitza S, Noordam R, Paüls-Vergés F, Rich SS, Rosendaal FR, Rudan I, Ryan KA, Souto JC, van Rooij FJ, Wang H, Zhao W, Becker LC, Beswick A, Brown MR, Cade BE, Campbell H, Cho K, Crapo JD, Curran JE, de Maat MP, Doyle M, Elliott P, Floyd JS, Fuchsberger C, Grarup N, Guo X, Harris SE, Hou L, Kolcic I, Kooperberg C, Menni C, Nauck M, O'Connell JR, Orrù V, Psaty BM, Räikkönen K, Smith JA, Soria JM, Stott DJ, van Hylckama Vlieg A, Watkins H, Willemsen G, Wilson P, Ben-Shlomo Y, Blangero J, Boomsma D, Cox SR, Dehghan A, Eriksson JG, Fiorillo E, Fornage M, Hansen T, Hayward C, Ikram MA, J… See abstract for full author list ➔ Huffman JE, et al. Among authors: tregouet da. medRxiv [Preprint]. 2023 Jun 12:2023.06.07.23291095. doi: 10.1101/2023.06.07.23291095. medRxiv. 2023. Update in: Blood. 2024 Nov 21;144(21):2248-2265. doi: 10.1182/blood.2023022596. PMID: 37398003 Free PMC article. Updated. Preprint.
Cerebral small vessel disease genomics and its implications across the lifespan.
Sargurupremraj M, Suzuki H, Jian X, Sarnowski C, Evans TE, Bis JC, Eiriksdottir G, Sakaue S, Terzikhan N, Habes M, Zhao W, Armstrong NJ, Hofer E, Yanek LR, Hagenaars SP, Kumar RB, van den Akker EB, McWhirter RE, Trompet S, Mishra A, Saba Y, Satizabal CL, Beaudet G, Petit L, Tsuchida A, Zago L, Schilling S, Sigurdsson S, Gottesman RF, Lewis CE, Aggarwal NT, Lopez OL, Smith JA, Valdés Hernández MC, van der Grond J, Wright MJ, Knol MJ, Dörr M, Thomson RJ, Bordes C, Le Grand Q, Duperron MG, Smith AV, Knopman DS, Schreiner PJ, Evans DA, Rotter JI, Beiser AS, Maniega SM, Beekman M, Trollor J, Stott DJ, Vernooij MW, Wittfeld K, Niessen WJ, Soumaré A, Boerwinkle E, Sidney S, Turner ST, Davies G, Thalamuthu A, Völker U, van Buchem MA, Bryan RN, Dupuis J, Bastin ME, Ames D, Teumer A, Amouyel P, Kwok JB, Bülow R, Deary IJ, Schofield PR, Brodaty H, Jiang J, Tabara Y, Setoh K, Miyamoto S, Yoshida K, Nagata M, Kamatani Y, Matsuda F, Psaty BM, Bennett DA, De Jager PL, Mosley TH, Sachdev PS, Schmidt R, Warren HR, Evangelou E, Trégouët DA; International Network against Thrombosis (INVENT) Consortium; International Headache Genomics Consortium (IHGC); Ikram MA, Wen W, DeCarli C, Srikanth VK,… See abstract for full author list ➔ Sargurupremraj M, et al. Among authors: tregouet da. Nat Commun. 2020 Dec 8;11(1):6285. doi: 10.1038/s41467-020-19111-2. Nat Commun. 2020. PMID: 33293549 Free PMC article.
Multi-ancestry polygenic risk scores for venous thromboembolism.
Jee YH, Thibord F, Dominguez A, Sept C, Boulier K, Venkateswaran V, Ding Y, Cherlin T, Verma SS, Faro VL, Bartz TM, Boland A, Brody JA, Deleuze JF, Emmerich J, Germain M, Johnson AD, Kooperberg C, Morange PE, Pankratz N, Psaty BM, Reiner AP, Smadja DM, Sitlani CM, Suchon P, Tang W, Trégouët DA, Zöllner S, Pasaniuc B, Damrauer SM, Sanna S, Snieder H; Lifelines Cohort Study; Kabrhel C, Smith NL, Kraft P; INVENT Consortium. Jee YH, et al. Among authors: tregouet da. medRxiv [Preprint]. 2024 Jan 10:2024.01.09.24300914. doi: 10.1101/2024.01.09.24300914. medRxiv. 2024. Update in: Hum Mol Genet. 2024 Sep 3;33(18):1584-1591. doi: 10.1093/hmg/ddae097. PMID: 38260294 Free PMC article. Updated. Preprint.
Multi-population GWAS for venous thromboembolism identifies novel loci followed by experimental validation in zebrafish.
Wolford BN, Zhao QY, Wu KH, Yu X, Richter CE, Bhatta L, Brumpton BM, Desch KC, Thibord F, Klarin D, Johnson AD, Tregouet DA, Damrauer SM, Smith NL, Lo Faro V, Tsuo K, Daly M, Neale B, Zhou W, Willer CJ, Shavit JA, Surakka I. Wolford BN, et al. Among authors: tregouet da. Blood Adv. 2025 Jun 24:bloodadvances.2024015790. doi: 10.1182/bloodadvances.2024015790. Online ahead of print. Blood Adv. 2025. PMID: 40554366
A Multi-Omics Approach Reveals Novel Regulators of Plasma Factor V Levels: highlight on CLEC4M as a Clearance Receptor.
Munsch G, Mohapatra A, van Hylckama Vlieg A, Kleber ME, Martinez-Perez A, Le NQ, Hindberg KD, Dusart PJ, Germain M, Thibord F, Deleuze JF, Delgado GE, Goumidi L, Suchon P, Saut N, Souto JC, Butler L, Soria JM, Hansen JB, März W, Rosendaal FR, Castoldi E, Peiretti F, Sabater-Lleal M, Tregouet DA, Morange PE. Munsch G, et al. Among authors: tregouet da. Blood. 2025 May 13:blood.2024027006. doi: 10.1182/blood.2024027006. Online ahead of print. Blood. 2025. PMID: 40359434
Correction to: Integrative Multiomics in the Lung Reveals a Protective Role of Asporin in Pulmonary Arterial Hypertension.
Hong J, Medzikovic L, Sun W, Wong B, Ruffenach G, Rhodes CJ, Brownstein A, Liang LL, Aryan L, Li M, Vadgama A, Kurt Z, Schwantes-An TH, Mickler EA, Gräf S, Eyries M, Lutz KA, Pauciulo MW, Trembath RC, Perros F, Montani D, Morrell NW, Soubrier F, Wilkins MR, Nichols WC, Aldred MA, Desai AA, Trégouët DA, Umar S, Saggar R, Channick R, Tuder RM, Geraci MW, Stearman RS, Yang X, Eghbali M. Hong J, et al. Among authors: tregouet da. Circulation. 2025 Apr 8;151(14):e921. doi: 10.1161/CIR.0000000000001331. Epub 2025 Apr 7. Circulation. 2025. PMID: 40193543 Free article. No abstract available.
Polygenic score integrating neurodegenerative and vascular risk informs dementia risk stratification.
D'Aoust T, Clocchiatti-Tuozzo S, Rivier CA, Mishra A, Hachiya T, Grenier-Boley B, Soumaré A, Duperron MG, Le Grand Q, Bouteloup V, Proust-Lima C, Samieri C, Neuffer J, Sargurupremraj M, Chêne G, Helmer C, Thibault M, Amouyel P, Lambert JC, Kamatani Y, Jacqmin-Gadda H, Tregouët DA, Inouye M, Dufouil C, Falcone GJ, Debette S. D'Aoust T, et al. Among authors: tregouet da. Alzheimers Dement. 2025 Mar;21(3):e70014. doi: 10.1002/alz.70014. Alzheimers Dement. 2025. PMID: 40042447 Free PMC article.
282 results