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A phase II study of REOLYSIN® (pelareorep) in combination with carboplatin and paclitaxel for patients with advanced malignant melanoma.
Mahalingam D, Fountzilas C, Moseley J, Noronha N, Tran H, Chakrabarty R, Selvaggi G, Coffey M, Thompson B, Sarantopoulos J. Mahalingam D, et al. Among authors: coffey m. Cancer Chemother Pharmacol. 2017 Apr;79(4):697-703. doi: 10.1007/s00280-017-3260-6. Epub 2017 Mar 13. Cancer Chemother Pharmacol. 2017. PMID: 28289863 Clinical Trial.
Pembrolizumab in Combination with the Oncolytic Virus Pelareorep and Chemotherapy in Patients with Advanced Pancreatic Adenocarcinoma: A Phase Ib Study.
Mahalingam D, Wilkinson GA, Eng KH, Fields P, Raber P, Moseley JL, Cheetham K, Coffey M, Nuovo G, Kalinski P, Zhang B, Arora SP, Fountzilas C. Mahalingam D, et al. Among authors: coffey m. Clin Cancer Res. 2020 Jan 1;26(1):71-81. doi: 10.1158/1078-0432.CCR-19-2078. Epub 2019 Nov 6. Clin Cancer Res. 2020. PMID: 31694832 Free PMC article. Clinical Trial.
Oncolytic virus-mediated expansion of dual-specific CAR T cells improves efficacy against solid tumors in mice.
Evgin L, Kottke T, Tonne J, Thompson J, Huff AL, van Vloten J, Moore M, Michael J, Driscoll C, Pulido J, Swanson E, Kennedy R, Coffey M, Loghmani H, Sanchez-Perez L, Olivier G, Harrington K, Pandha H, Melcher A, Diaz RM, Vile RG. Evgin L, et al. Among authors: coffey m. Sci Transl Med. 2022 Apr 13;14(640):eabn2231. doi: 10.1126/scitranslmed.abn2231. Epub 2022 Apr 13. Sci Transl Med. 2022. PMID: 35417192 Free PMC article.
Neutralizing Antibodies Impair the Oncolytic Efficacy of Reovirus but Permit Effective Combination with T cell-Based Immunotherapies.
Groeneveldt C, Kinderman P, Griffioen L, Rensing O, Labrie C, van den Wollenberg DJM, Hoeben RC, Coffey M, Loghmani H, Verdegaal EME, Welters MJP, van der Burg SH, van Hall T, van Montfoort N. Groeneveldt C, et al. Among authors: coffey m. Cancer Immunol Res. 2024 Mar 4;12(3):334-349. doi: 10.1158/2326-6066.CIR-23-0480. Cancer Immunol Res. 2024. PMID: 38194598 Free PMC article.
A Phase II Randomized Study of Paclitaxel alone or combined with Pelareorep with or without Avelumab in Metastatic Hormone Receptor Positive Breast Cancer: the BRACELET-01/PrE0113 study.
Clark AS, Zhao F, Klein P, Montero AJ, Falkson C, Krill-Jackson E, Rowland K, Sardesai S, Incorvati J, Dillon P, Wolff AC, Trauger R, Heineman TC, Coffey MC, Miller KD. Clark AS, et al. Among authors: coffey mc. Clin Cancer Res. 2025 Apr 29. doi: 10.1158/1078-0432.CCR-24-2701. Online ahead of print. Clin Cancer Res. 2025. PMID: 40300087
771 results