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Canakinumab (ACZ885, a fully human IgG1 anti-IL-1β mAb) induces sustained remission in pediatric patients with cryopyrin-associated periodic syndrome (CAPS).
Kuemmerle-Deschner JB, Ramos E, Blank N, Roesler J, Felix SD, Jung T, Stricker K, Chakraborty A, Tannenbaum S, Wright AM, Rordorf C. Kuemmerle-Deschner JB, et al. Among authors: felix sd. Arthritis Res Ther. 2011 Feb 28;13(1):R34. doi: 10.1186/ar3266. Arthritis Res Ther. 2011. PMID: 21356079 Free PMC article. Clinical Trial.
Influenza and meningococcal vaccinations are effective in healthy subjects treated with the interleukin-1 beta-blocking antibody canakinumab: results of an open-label, parallel group, randomized, single-center study.
Chioato A, Noseda E, Felix SD, Stevens M, Del Giudice G, Fitoussi S, Kleinschmidt A. Chioato A, et al. Among authors: felix sd. Clin Vaccine Immunol. 2010 Dec;17(12):1952-7. doi: 10.1128/CVI.00175-10. Epub 2010 Oct 20. Clin Vaccine Immunol. 2010. PMID: 20962212 Free PMC article. Clinical Trial.