Huang X - Search Results

1

Terminal Alkyne-Modified DNA Aptamers with Enhanced Protein Binding Affinities.

Kohn EM, Konovalov K, Gomez CA, Hoover GN, Yik AK, Huang X, Martell JD. Kohn EM, et al. Among authors: huang x. ACS Chem Biol. 2023 Sep 15;18(9):1976-1984. doi: 10.1021/acschembio.3c00183. Epub 2023 Aug 2. ACS Chem Biol. 2023. PMID: 37531184

2

Conformational selection turns on phenylalanine hydroxylase.

Konovalov KA, Wang W, Huang X. Konovalov KA, et al. Among authors: huang x. J Biol Chem. 2018 Dec 21;293(51):19544-19545. doi: 10.1074/jbc.H118.006676. J Biol Chem. 2018. PMID: 30578407 Free PMC article.

3

8-Oxo-guanine DNA damage induces transcription errors by escaping two distinct fidelity control checkpoints of RNA polymerase II.

Konovalov KA, Pardo-Avila F, Tse CKM, Oh J, Wang D, Huang X. Konovalov KA, et al. Among authors: huang x. J Biol Chem. 2019 Mar 29;294(13):4924-4933. doi: 10.1074/jbc.RA118.007333. Epub 2019 Feb 4. J Biol Chem. 2019. PMID: 30718278 Free PMC article.

4

A comprehensive mechanism for 5-carboxylcytosine-induced transcriptional pausing revealed by Markov state models.

Konovalov KA, Wang W, Wang G, Goonetilleke EC, Gao X, Wang D, Huang X. Konovalov KA, et al. Among authors: huang x. J Biol Chem. 2021 Jan-Jun;296:100735. doi: 10.1016/j.jbc.2021.100735. Epub 2021 May 13. J Biol Chem. 2021. PMID: 33991521 Free PMC article.

5

Markov State Models to Study the Functional Dynamics of Proteins in the Wake of Machine Learning.

Konovalov KA, Unarta IC, Cao S, Goonetilleke EC, Huang X. Konovalov KA, et al. Among authors: huang x. JACS Au. 2021 Aug 4;1(9):1330-1341. doi: 10.1021/jacsau.1c00254. eCollection 2021 Sep 27. JACS Au. 2021. PMID: 34604842 Free PMC article. Review.

6

Disease mutations and phosphorylation alter the allosteric pathways involved in autoinhibition of protein phosphatase 2A.

Konovalov KA, Wu CG, Qiu Y, Balakrishnan VK, Parihar PS, O'Connor MS, Xing Y, Huang X. Konovalov KA, et al. Among authors: huang x. J Chem Phys. 2023 Jun 7;158(21):215101. doi: 10.1063/5.0150272. J Chem Phys. 2023. PMID: 37260014 Free PMC article.

7

GraphVAMPnets for uncovering slow collective variables of self-assembly dynamics.

Liu B, Xue M, Qiu Y, Konovalov KA, O'Connor MS, Huang X. Liu B, et al. Among authors: huang x. J Chem Phys. 2023 Sep 7;159(9):094901. doi: 10.1063/5.0158903. J Chem Phys. 2023. PMID: 37655771 Free PMC article.

8

Ultrahigh-Throughput Directed Evolution of Polymer-Degrading Enzymes Using Yeast Display.

Cribari MA, Unger MJ, Unarta IC, Ogorek AN, Huang X, Martell JD. Cribari MA, et al. Among authors: huang x. J Am Chem Soc. 2023 Dec 20;145(50):27380-27389. doi: 10.1021/jacs.3c08291. Epub 2023 Dec 5. J Am Chem Soc. 2023. PMID: 38051911 Free PMC article.

9

Transcription-Coupled Template Reconfiguration of 8-Oxoguanine for Error-Prone Transcription Revealed by Time-Resolved X-ray Crystallography and Molecular Dynamics.

Oh J, Konovalov KA, Hou P, Chong J, Huang X, Wang D. Oh J, et al. Among authors: huang x. J Am Chem Soc. 2025 May 14;147(19):16396-16403. doi: 10.1021/jacs.5c02687. Epub 2025 Apr 30. J Am Chem Soc. 2025. PMID: 40305462 Free PMC article.

10

Memory Unlocks the Future of Biomolecular Dynamics: Transformative Tools to Uncover Physical Insights Accurately and Efficiently.

Dominic AJ 3rd, Cao S, Montoya-Castillo A, Huang X. Dominic AJ 3rd, et al. Among authors: huang x. J Am Chem Soc. 2023 May 10;145(18):9916-9927. doi: 10.1021/jacs.3c01095. Epub 2023 Apr 27. J Am Chem Soc. 2023. PMID: 37104720 Review.

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