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Mouse intraductal modeling of primary ductal carcinoma in situ.
Hutten SJ, Behbod F, Scheele CLGJ, Jonkers J. Hutten SJ, et al. Among authors: jonkers j. STAR Protoc. 2023 Sep 15;4(3):102526. doi: 10.1016/j.xpro.2023.102526. Epub 2023 Aug 30. STAR Protoc. 2023. PMID: 37651235 Free PMC article.
Metabolic adaptation towards glycolysis supports resistance to neoadjuvant chemotherapy in early triple negative breast cancers.
Derouane F, Desgres M, Moroni C, Ambroise J, Berlière M, Van Bockstal MR, Galant C, van Marcke C, Vara-Messler M, Hutten SJ, Jonkers J, Mourao L, Scheele CLGJ, Duhoux FP, Corbet C. Derouane F, et al. Among authors: jonkers j. Breast Cancer Res. 2024 Feb 19;26(1):29. doi: 10.1186/s13058-024-01788-8. Breast Cancer Res. 2024. PMID: 38374113 Free PMC article.
SRBD1, a highly conserved gene required for chromosome individualization.
Raaijmakers JA, Janssen LME, Mazouzi A, Hondema ALH, Borza R, Fish A, Elbatsh AMO, Kazokaitė-Adomaitienė J, Vaquero-Siguero N, Mayayo-Peralta I, Nahidiazar L, Friskes A, Hoekman L, Bleijerveld OB, Hoencamp C, Moser SC, Jonkers J, Jalink K, Zwart W, Celie PHN, Rowland BD, Perrakis A, Brummelkamp TR, Medema RH. Raaijmakers JA, et al. Among authors: jonkers j. Cell Rep. 2025 Apr 22;44(4):115443. doi: 10.1016/j.celrep.2025.115443. Epub 2025 Mar 18. Cell Rep. 2025. PMID: 40106440 Free article.
Genome-scale mapping of DNA damage suppressors through phenotypic CRISPR-Cas9 screens.
Zhao Y, Tabet D, Rubio Contreras D, Lao L, Kousholt AN, Weile J, Melo H, Hoeg L, Feng S, Coté AG, Lin ZY, Setiaputra D, Jonkers J, Gingras AC, Gómez Herreros F, Roth FP, Durocher D. Zhao Y, et al. Among authors: jonkers j. Mol Cell. 2023 Aug 3;83(15):2792-2809.e9. doi: 10.1016/j.molcel.2023.06.025. Epub 2023 Jul 20. Mol Cell. 2023. PMID: 37478847 Free PMC article.
G6PC3 promotes genome maintenance and is a candidate mammary tumor suppressor.
Li X, Rossing M, Moisés da Silva A, Bose M, Gudjónsson T, Benada J, Thatte J, Johansen JV, Börcsök J, van der Gulden H, Song JY, Menezes R, Tajik A, Sena L, Szallasi Z, Frödin M, Jonkers J, Nielsen FC, Sørensen CS. Li X, et al. Among authors: jonkers j. JCI Insight. 2025 Apr 22;10(11):e186747. doi: 10.1172/jci.insight.186747. eCollection 2025 Jun 9. JCI Insight. 2025. PMID: 40261702 Free article.
The pan-cancer proteome atlas, a mass spectrometry-based landscape for discovering tumor biology, biomarkers, and therapeutic targets.
Knol JC, Lyu M, Böttger F, Nunes Monteiro M, Pham TV, Rolfs F, Vallés-Martí A, Schelfhorst T, de Goeij-de Haas RR, Bijnsdorp IV, Wang S, Zhang F, A J, Westerman BA, Sitek B, Lehtiö J, Koster J, IJzermans JNM, van Laarhoven HWM, Bijlsma MF, Medema JP, Henneman AA, Piersma SR, Brakenhoff RH, Cloos J, Cordo' V, de Jong D, Kazemier G, Koppers-Lalic D, Labots M, Le Large TYS, Martens JWM, Meijerink JPP, Mumtaz M, Scheepbouwer C, Kibbelaar RE, Noske DP, Steenbergen RDM, van Grieken NCT, van Houdt W, Giovannetti E, van Leenders GJLH, Jonkers J, Liu T, Yan M, Zhan X, Guo T, Jimenez CR. Knol JC, et al. Among authors: jonkers j. Cancer Cell. 2025 May 27:S1535-6108(25)00212-0. doi: 10.1016/j.ccell.2025.05.003. Online ahead of print. Cancer Cell. 2025. PMID: 40446800
The C-terminal Kinase Domain-Binding and Suppression Motif Prevents Constitutive Activation of FGFR2.
Zingg D, Lin CC, Yemelyanenko J, Wieteska L, Kas SM, Bleijerveld OB, Chao X, Bhin J, Lutz C, Wientjens E, Klarenbeek S, Zanetti G, Annunziato S, Siteur B, van der Burg E, Drenth AP, van de Ven M, Wessels LFA, Altelaar M, Ladbury JE, Jonkers J. Zingg D, et al. Among authors: jonkers j. Cancer Res. 2025 Jun 24. doi: 10.1158/0008-5472.CAN-24-3349. Online ahead of print. Cancer Res. 2025. PMID: 40554806
The class II myosin MYH4 safeguards genome integrity and suppresses tumor progression.
Thatte J, Moisés da Silva A, Börcsök J, Gudjónsson T, Benada J, Li X, Bose M, van der Gulden H, Song JY, Menezes R, Martín-Doncel E, Toledo L, Petrosius V, Brakebusch C, Jonkers J, Nielsen FC, Rossing M, Sørensen CS. Thatte J, et al. Among authors: jonkers j. J Clin Invest. 2025 Jun 2;135(11):e188165. doi: 10.1172/JCI188165. eCollection 2025 Jun 2. J Clin Invest. 2025. PMID: 40454487 Free PMC article.
Deep learning for predicting invasive recurrence of ductal carcinoma in situ: leveraging histopathology images and clinical features.
Doyle S, Lips EH, Marcus E, Mulder L, Liu YH, Canton FD, Kootstra T, van Seijen MM, Bouybayoune I, Sawyer EJ, Thompson AM, Pinder SE, Sánchez CI, Teuwen J, Wesseling J; Grand Challenge PRECISION Consortium. Doyle S, et al. EBioMedicine. 2025 Jun;116:105750. doi: 10.1016/j.ebiom.2025.105750. Epub 2025 May 28. EBioMedicine. 2025. PMID: 40440915 Free PMC article.
370 results