Tonn T - Search Results

1

ErbB2 (HER2)-CAR-NK-92 cells for enhanced immunotherapy of metastatic fusion-driven alveolar rhabdomyosarcoma.

Heim C, Moser LM, Kreyenberg H, Bonig HB, Tonn T, Wels WS, Gradhand E, Ullrich E, Meister MT, Koerkamp MG, Holstege FCP, Drost J, Klusmann JH, Bader P, Merker M, Rettinger E. Heim C, et al. Among authors: tonn t. Front Immunol. 2023 Aug 18;14:1228894. doi: 10.3389/fimmu.2023.1228894. eCollection 2023. Front Immunol. 2023. PMID: 37662907 Free PMC article.

2

Prediction of humoral and cellular immune response to COVID-19 mRNA vaccination by TTV load in kidney transplant recipients and hemodialysis patients.

Graninger M, Stumpf J, Bond G, Görzer I, Springer DN, Kessel F, Kröger H, Frank K, Tonn T, Hugo C, Puchhammer-Stöckl E. Graninger M, et al. Among authors: tonn t. J Clin Virol. 2023 May;162:105428. doi: 10.1016/j.jcv.2023.105428. Epub 2023 Mar 24. J Clin Virol. 2023. PMID: 36989730 Free PMC article.

3

Intracranial injection of natural killer cells engineered with a HER2-targeted chimeric antigen receptor in patients with recurrent glioblastoma.

Burger MC, Forster MT, Romanski A, Straßheimer F, Macas J, Zeiner PS, Steidl E, Herkt S, Weber KJ, Schupp J, Lun JH, Strecker MI, Wlotzka K, Cakmak P, Opitz C, George R, Mildenberger IC, Nowakowska P, Zhang C, Röder J, Müller E, Ihrig K, Langen KJ, Rieger MA, Herrmann E, Bonig H, Harter PN, Reiss Y, Hattingen E, Rödel F, Plate KH, Tonn T, Senft C, Steinbach JP, Wels WS. Burger MC, et al. Among authors: tonn t. Neuro Oncol. 2023 Nov 2;25(11):2058-2071. doi: 10.1093/neuonc/noad087. Neuro Oncol. 2023. PMID: 37148198 Free PMC article.

4

Live-cell imaging for analysis of the NK cell immunological synapse.

Wotschel N, Montero PO, Wels WS, Tonn T, Eitler J. Wotschel N, et al. Among authors: tonn t. Methods Cell Biol. 2023;178:1-12. doi: 10.1016/bs.mcb.2022.09.023. Epub 2022 Nov 12. Methods Cell Biol. 2023. PMID: 37516519

5

Editorial: Translating NK cell scientific research to clinical product manufacturing.

Ullrich E, Huppert V, Tonn T, Leung W. Ullrich E, et al. Among authors: tonn t. Front Immunol. 2023 Aug 23;14:1229417. doi: 10.3389/fimmu.2023.1229417. eCollection 2023. Front Immunol. 2023. PMID: 37680640 Free PMC article. No abstract available.

6

Engineering NK-CAR.19 cells with the IL-15/IL-15Rα complex improved proliferation and anti-tumor effect in vivo.

Silvestre RN, Eitler J, de Azevedo JTC, Tirapelle MC, Fantacini DMC, de Souza LEB, Swiech K, Covas DT, Calado RT, Montero PO, Malmegrim KCR, Figueiredo ML, Tonn T, Picanço-Castro V. Silvestre RN, et al. Among authors: tonn t. Front Immunol. 2023 Sep 25;14:1226518. doi: 10.3389/fimmu.2023.1226518. eCollection 2023. Front Immunol. 2023. PMID: 37818365 Free PMC article.

7

Preclinical assessment of CAR-NK cell-mediated killing efficacy and pharmacokinetics in a rapid zebrafish xenograft model of metastatic breast cancer.

Murali Shankar N, Ortiz-Montero P, Kurzyukova A, Rackwitz W, Künzel SR, Wels WS, Tonn T, Knopf F, Eitler J. Murali Shankar N, et al. Among authors: tonn t. Front Immunol. 2023 Oct 11;14:1254821. doi: 10.3389/fimmu.2023.1254821. eCollection 2023. Front Immunol. 2023. PMID: 37885894 Free PMC article.

8

Bortezomib promotes the TRAIL-mediated killing of resistant rhabdomyosarcoma by ErbB2/Her2-targeted CAR-NK-92 cells via DR5 upregulation.

Heim C, Hartig L, Weinelt N, Moser LM, Salzmann-Manrique E, Merker M, Wels WS, Tonn T, Bader P, Klusmann JH, van Wijk SJL, Rettinger E. Heim C, et al. Among authors: tonn t. Mol Ther Oncol. 2024 Apr 11;32(2):200802. doi: 10.1016/j.omton.2024.200802. eCollection 2024 Jun 20. Mol Ther Oncol. 2024. PMID: 38706988 Free PMC article.

9

ErbB2/HER2-targeted CAR-NK cells eliminate breast cancer cells in an organoid model that recapitulates tumor progression.

Röder J, Alekseeva T, Kiefer A, Kühnel I, Prüfer M, Zhang C, Bodden M, Rosigkeit S, Waldmann A, Tonn T, Bockamp E, Stein S, Wels WS. Röder J, et al. Among authors: tonn t. Mol Ther. 2025 Apr 24:S1525-0016(25)00312-0. doi: 10.1016/j.ymthe.2025.04.033. Online ahead of print. Mol Ther. 2025. PMID: 40285353 Free article.

10

Dysregulated monocyte compartment in PACS patients.

Kronstein-Wiedemann R, Teichert M, Michel E, Berg J, Robinson G, Tausche K, Kolditz M, Bergleiter J, Thiel J, Koschel D, Künzel SR, Hölig K, Tonn T, Rossol M. Kronstein-Wiedemann R, et al. Among authors: tonn t. Front Immunol. 2025 Jun 6;16:1613034. doi: 10.3389/fimmu.2025.1613034. eCollection 2025. Front Immunol. 2025. PMID: 40547035 Free PMC article.

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