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Statins improve endothelial function via suppression of epigenetic-driven EndMT.
Liu C, Shen M, Tan WLW, Chen IY, Liu Y, Yu X, Yang H, Zhang A, Liu Y, Zhao MT, Ameen M, Zhang M, Gross ER, Qi LS, Sayed N, Wu JC. Liu C, et al. Among authors: qi ls. Nat Cardiovasc Res. 2023 May;2(5):467-485. doi: 10.1038/s44161-023-00267-1. Epub 2023 May 8. Nat Cardiovasc Res. 2023. PMID: 37693816 Free PMC article.
Therapeutic genome editing in cardiovascular diseases.
Nishiga M, Qi LS, Wu JC. Nishiga M, et al. Among authors: qi ls. Adv Drug Deliv Rev. 2021 Jan;168:147-157. doi: 10.1016/j.addr.2020.02.003. Epub 2020 Feb 21. Adv Drug Deliv Rev. 2021. PMID: 32092381 Free PMC article. Review.
CRISPRi/a Screening with Human iPSCs.
Nishiga M, Qi LS, Wu JC. Nishiga M, et al. Among authors: qi ls. Methods Mol Biol. 2021;2320:261-281. doi: 10.1007/978-1-0716-1484-6_23. Methods Mol Biol. 2021. PMID: 34302664 Free PMC article.
CRISPRi/a screens in human iPSC-cardiomyocytes identify glycolytic activation as a druggable target for doxorubicin-induced cardiotoxicity.
Liu C, Shen M, Liu Y, Manhas A, Zhao SR, Zhang M, Belbachir N, Ren L, Zhang JZ, Caudal A, Nishiga M, Thomas D, Zhang A, Yang H, Zhou Y, Ameen M, Sayed N, Rhee JW, Qi LS, Wu JC. Liu C, et al. Among authors: qi ls. Cell Stem Cell. 2024 Dec 5;31(12):1760-1776.e9. doi: 10.1016/j.stem.2024.10.007. Epub 2024 Nov 7. Cell Stem Cell. 2024. PMID: 39515331
CRISPR-mediated live imaging of genome editing and transcription.
Wang H, Nakamura M, Abbott TR, Zhao D, Luo K, Yu C, Nguyen CM, Lo A, Daley TP, La Russa M, Liu Y, Qi LS. Wang H, et al. Among authors: qi ls. Science. 2019 Sep 20;365(6459):1301-1305. doi: 10.1126/science.aax7852. Epub 2019 Sep 5. Science. 2019. PMID: 31488703
140 results