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Imaging-based chromatin and epigenetic age, ImAge, quantitates aging and rejuvenation.
Alvarez-Kuglen M, Rodriguez D, Qin H, Ninomiya K, Fiengo L, Farhy C, Hsu WM, Havas A, Feng GS, Roberts AJ, Anderson RM, Serrano M, Adams PD, Sharpee TO, Terskikh AV. Alvarez-Kuglen M, et al. Among authors: havas a. Res Sq [Preprint]. 2023 Nov 7:rs.3.rs-3479973. doi: 10.21203/rs.3.rs-3479973/v1. Res Sq. 2023. Update in: Nat Aging. 2024 Sep;4(9):1308-1327. doi: 10.1038/s43587-024-00685-1. PMID: 37986947 Free PMC article. Updated. Preprint.
The role of aging in cancer.
Havas A, Yin S, Adams PD. Havas A, et al. Mol Oncol. 2022 Sep;16(18):3213-3219. doi: 10.1002/1878-0261.13302. Mol Oncol. 2022. PMID: 36128609 Free PMC article.
Upregulation of PD-L1 in Senescence and Aging.
Onorati A, Havas AP, Lin B, Rajagopal J, Sen P, Adams PD, Dou Z. Onorati A, et al. Among authors: havas ap. Mol Cell Biol. 2022 Oct 20;42(10):e0017122. doi: 10.1128/mcb.00171-22. Epub 2022 Sep 26. Mol Cell Biol. 2022. PMID: 36154662 Free PMC article.
Dynamic enhancer interactome promotes senescence and aging.
Wang L, Donahue G, Zhang C, Havas A, Lei X, Xu C, Wang W, Vahedi G, Adams PD, Berger SL. Wang L, et al. Among authors: havas a. bioRxiv [Preprint]. 2023 May 22:2023.05.22.541769. doi: 10.1101/2023.05.22.541769. bioRxiv. 2023. PMID: 37292952 Free PMC article. Preprint.
Histone chaperone HIRA, promyelocytic leukemia protein, and p62/SQSTM1 coordinate to regulate inflammation during cell senescence.
Dasgupta N, Lei X, Shi CH, Arnold R, Teneche MG, Miller KN, Rajesh A, Davis A, Anschau V, Campos AR, Gilson R, Havas A, Yin S, Chua ZM, Liu T, Proulx J, Alcaraz M, Rather MI, Baeza J, Schultz DC, Yip KY, Berger SL, Adams PD. Dasgupta N, et al. Among authors: havas a. Mol Cell. 2024 Sep 5;84(17):3271-3287.e8. doi: 10.1016/j.molcel.2024.08.006. Epub 2024 Aug 22. Mol Cell. 2024. PMID: 39178863
ImAge quantitates aging and rejuvenation.
Alvarez-Kuglen M, Ninomiya K, Qin H, Rodriguez D, Fiengo L, Farhy C, Hsu WM, Kirk B, Havas A, Feng GS, Roberts AJ, Anderson RM, Serrano M, Adams PD, Sharpee TO, Terskikh AV. Alvarez-Kuglen M, et al. Among authors: havas a. Nat Aging. 2024 Sep;4(9):1308-1327. doi: 10.1038/s43587-024-00685-1. Epub 2024 Aug 29. Nat Aging. 2024. PMID: 39210148
Mitochondrial metabolism and epigenetic crosstalk drive the SASP.
Passos J, Martini H, Birch J, Marques F, Victorelli S, Lagnado A, Pirius N, Franco A, Lee G, Han Y, Rowsey J, Gaspar-Maia A, Havas A, Murad R, Lei X, Porritt R, Maddocks O, Jurk D, Khosla S, Adams P. Passos J, et al. Among authors: havas a. Res Sq [Preprint]. 2024 Dec 5:rs.3.rs-5278203. doi: 10.21203/rs.3.rs-5278203/v1. Res Sq. 2024. PMID: 39678326 Free PMC article. Preprint.
37 results