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SON is an essential m6A target for hematopoietic stem cell fate.
Luo H, Cortés-López M, Tam CL, Xiao M, Wakiro I, Chu KL, Pierson A, Chan M, Chang K, Yang X, Fecko D, Han G, Ahn EE, Morris QD, Landau DA, Kharas MG. Luo H, et al. Among authors: kharas mg. Cell Stem Cell. 2023 Dec 7;30(12):1658-1673.e10. doi: 10.1016/j.stem.2023.11.006. Cell Stem Cell. 2023. PMID: 38065069 Free PMC article.
Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia.
Järås M, Miller PG, Chu LP, Puram RV, Fink EC, Schneider RK, Al-Shahrour F, Peña P, Breyfogle LJ, Hartwell KA, McConkey ME, Cowley GS, Root DE, Kharas MG, Mullally A, Ebert BL. Järås M, et al. Among authors: kharas mg. J Exp Med. 2014 Apr 7;211(4):605-12. doi: 10.1084/jem.20131033. Epub 2014 Mar 10. J Exp Med. 2014. PMID: 24616378 Free PMC article.
S6 kinase 2 potentiates interleukin-3-driven cell proliferation.
Cruz R, Hedden L, Boyer D, Kharas MG, Fruman DA, Lee-Fruman KK. Cruz R, et al. Among authors: kharas mg. J Leukoc Biol. 2005 Dec;78(6):1378-85. doi: 10.1189/jlb.0405225. Epub 2005 Oct 4. J Leukoc Biol. 2005. PMID: 16204634 Free PMC article.
IKZF2 Drives Leukemia Stem Cell Self-Renewal and Inhibits Myeloid Differentiation.
Park SM, Cho H, Thornton AM, Barlowe TS, Chou T, Chhangawala S, Fairchild L, Taggart J, Chow A, Schurer A, Gruet A, Witkin MD, Kim JH, Shevach EM, Krivtsov A, Armstrong SA, Leslie C, Kharas MG. Park SM, et al. Among authors: kharas mg. Cell Stem Cell. 2019 Jan 3;24(1):153-165.e7. doi: 10.1016/j.stem.2018.10.016. Epub 2018 Nov 21. Cell Stem Cell. 2019. PMID: 30472158 Free PMC article.
Rubbing Out Leukemia Stem Cells by Erasing the Eraser.
Cheng Y, Luo H, Kharas MG. Cheng Y, et al. Among authors: kharas mg. Cell Stem Cell. 2020 Jul 2;27(1):3-5. doi: 10.1016/j.stem.2020.06.009. Cell Stem Cell. 2020. PMID: 32619516 Free PMC article.
85 results