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Page 1
The landscape of immune dysregulation in Crohn's disease revealed through single-cell transcriptomic profiling in the ileum and colon.
Kong L, Pokatayev V, Lefkovith A, Carter GT, Creasey EA, Krishna C, Subramanian S, Kochar B, Ashenberg O, Lau H, Ananthakrishnan AN, Graham DB, Deguine J, Xavier RJ. Kong L, et al. Among authors: ananthakrishnan an. Immunity. 2023 Dec 12;56(12):2855. doi: 10.1016/j.immuni.2023.10.017. Immunity. 2023. PMID: 38091954 Free article. No abstract available.
A pilot study to identify blood-based markers associated with response to treatment with Vedolizumab in patients with Inflammatory Bowel Disease.
Rioux JD, Boucher G, Forest A, Bouchard B, Coderre L, Daneault C, Frayne IR, Legault JT; iGenoMed Consortium; Bitton A, Ananthakrishnan A, Lesage S, Xavier RJ, Des Rosiers C. Rioux JD, et al. medRxiv [Preprint]. 2024 Sep 22:2024.09.19.24314034. doi: 10.1101/2024.09.19.24314034. medRxiv. 2024. PMID: 39371119 Free PMC article. Preprint.
Single-cell and spatial transcriptomics of stricturing Crohn's disease highlights a fibrosis-associated network.
Kong L, Subramanian S, Segerstolpe Å, Tran V, Shih AR, Carter GT, Kunitake H, Twardus SW, Li J, Gandhi S, Kaper ME, Cauley C, Chen EJ, Porter CBM, Delorey TM, Bordeianou L, Ricciardi R, Ananthakrishnan AN, Lau H, Graham DB, Hodin R, Deguine J, Smillie CS, Xavier RJ. Kong L, et al. Among authors: ananthakrishnan an. Nat Genet. 2025 Jun 25. doi: 10.1038/s41588-025-02225-y. Online ahead of print. Nat Genet. 2025. PMID: 40562913
Editorial: Getting to the Heart of the Matter in IBD.
Ananthakrishnan AN. Ananthakrishnan AN. Aliment Pharmacol Ther. 2025 Jul;62(1):89-90. doi: 10.1111/apt.70177. Epub 2025 May 20. Aliment Pharmacol Ther. 2025. PMID: 40391742 No abstract available.
Clinical outcomes in Crohn's disease patients with short bowel syndrome on home parenteral nutrition are comparable to those with short bowel syndrome from other etiologies.
Sasson AN, Noelting J, Schwenger KJP, Ghorbani Y, Armstrong D, Raman M, Duerksen DR, Whittaker S, Lu Y, Jurewitsch B, Gramlich L, Ananthakrishnan AN, Allard JP. Sasson AN, et al. Among authors: ananthakrishnan an. Clin Nutr. 2025 Jun;49:149-156. doi: 10.1016/j.clnu.2025.04.015. Epub 2025 Apr 24. Clin Nutr. 2025. PMID: 40305998
Prevention and interception trials in inflammatory bowel disease: an international taskforce assessment on clinical trial design.
Honap S, Agrinier N, Torres J, Croitoru K, Lee SH, Turpin W, Ungaro RC, Agrawal M, Peter I, Turner D, Dotan I, Hart AL, Netter P, D'Haens G, Rubin DT, Ng SC, Gearry R, Jairath V, Ananthakrishnan AN, Danese S, Colombel JF, Peyrin-Biroulet L. Honap S, et al. Among authors: ananthakrishnan an. Lancet Gastroenterol Hepatol. 2025 Jun;10(6):593-604. doi: 10.1016/S2468-1253(24)00439-4. Epub 2025 Apr 2. Lancet Gastroenterol Hepatol. 2025. PMID: 40187359 Review.
Treat-to-target of endoscopic remission in patients with inflammatory bowel disease in symptomatic remission on advanced therapies (QUOTIENT): rationale, design and protocol for an open-label, multicentre, pragmatic, randomised controlled trial.
Singh S, Nguyen JD, Fudman DI, Gerich ME, Shah SA, Hudesman D, McConnell RA, Lukin DJ, Flynn AD, Hwang C, Sprung B, Gaidos JKJ, Mattar MC, Rubin DT, Hashash JG, Metwally M, Ali T, Ma C, Hoentjen F, Narula N, Bessissow T, Rosenfeld G, McCurdy JD, Ananthakrishnan AN, Cross RK, Rodriguez Gaytan JR, Gurrola ES, Patel S, Siegel CA, Melmed GY, Weaver SA, Power S, Zou G, Jairath V, Hou JK. Singh S, et al. Among authors: ananthakrishnan an. BMJ Open Gastroenterol. 2025 Mar 31;12(1):e001615. doi: 10.1136/bmjgast-2024-001615. BMJ Open Gastroenterol. 2025. PMID: 40164445 Free PMC article.
422 results