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Neoadjuvant radioimmunotherapy in pancreatic cancer enhances effector T cell infiltration and shortens their distances to tumor cells.
Wang J, Gai J, Zhang T, Niu N, Qi H, Thomas DL 2nd, Li K, Xia T, Rodriguez C, Parkinson R, Durham J, McPhaul T, Narang AK, Anders RA, Osipov A, Wang H, He J, Laheru DA, Herman JM, Lee V, Jaffee EM, Thompson ED, Zhu Q, Zheng L. Wang J, et al. Among authors: thompson ed. Sci Adv. 2024 Feb 9;10(6):eadk1827. doi: 10.1126/sciadv.adk1827. Epub 2024 Feb 7. Sci Adv. 2024. PMID: 38324679 Free PMC article.
Fibroblasts in the Aged Pancreas Drive Pancreatic Cancer Progression.
Zabransky DJ, Chhabra Y, Fane ME, Kartalia E, Leatherman JM, Hüser L, Zimmerman JW, Delitto D, Han S, Armstrong TD, Charmsaz S, Guinn S, Pramod S, Thompson ED, Hughes SJ, O'Connell J, Egan JM, Jaffee EM, Weeraratna AT. Zabransky DJ, et al. Among authors: thompson ed. Cancer Res. 2024 Apr 15;84(8):1221-1236. doi: 10.1158/0008-5472.CAN-24-0086. Cancer Res. 2024. PMID: 38330147 Free PMC article.
A phase II study of neoadjuvant GVAX and cyclophosphamide combined with nivolumab and SBRT followed by surgery in borderline resectable pancreatic adenocarcinoma.
Agarwal P, Guo M, Munjal K, Qi H, Parkinson R, Ferguson A, Mitchell C, Harrison J, Anders RA, Thompson ED, Wang H, De Jesus A, Zheng L, He J, Burkhart R, Narang A, George B, Jaffee EM, Yarchoan M, Laheru D, Osipov A. Agarwal P, et al. Among authors: thompson ed. Clin Cancer Res. 2025 May 23. doi: 10.1158/1078-0432.CCR-24-3403. Online ahead of print. Clin Cancer Res. 2025. PMID: 40407726
Spatial Proteomics and Transcriptomics Reveal Early Immune Cell Organization in Pancreatic Intraepithelial Neoplasia.
Lyman MR, Mitchell JT, Raghavan S, Kagohara LT, Huff AL, Haldar SD, Shin SM, Guinn S, Barrett B, Longway G, Hernandez A, Coyne EM, Yuan X, Andaloori L, Lai J, Liu YZ, Karchin R, Gupta A, Kiemen AL, Forjaz A, Wirtz D, Wu PH, Deshpande A, Lee JW, Armstrong TD, Azad NS, Zimmerman JW, Wood LD, Anders RA, Thompson ED, Jaffee EM, Fertig EJ, Ho WJ, Zaidi N. Lyman MR, et al. Among authors: thompson ed. JCI Insight. 2025 Jun 26:e191595. doi: 10.1172/jci.insight.191595. Online ahead of print. JCI Insight. 2025. PMID: 40569674 Free article.
Tumor immune microenvironment alterations associated with progression in human intraductal papillary mucinous neoplasms.
Jamouss KT, Damanakis AI, Cornwell AC, Jongepier M, Trujillo MA, Pflüger MJ, Kawalerski R, Maalouf A, Hirose K, Datta S, Sipes A, Pedro BA, Gudmundsson E, Assarzadegan N, Engle L, Scharpf RB, Kawamoto S, Thompson ED, Wood LD. Jamouss KT, et al. Among authors: thompson ed. J Pathol. 2025 May;266(1):40-50. doi: 10.1002/path.6402. Epub 2025 Feb 25. J Pathol. 2025. PMID: 40001347
157 results