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Genome-wide association studies and Mendelian randomization analyses provide insights into the causes of early-onset colorectal cancer.
Laskar RS, Qu C, Huyghe JR, Harrison T, Hayes RB, Cao Y, Campbell PT, Steinfelder R, Talukdar FR, Brenner H, Ogino S, Brendt S, Bishop DT, Buchanan DD, Chan AT, Cotterchio M, Gruber SB, Gsur A, van Guelpen B, Jenkins MA, Keku TO, Lynch BM, Le Marchand L, Martin RM, McCarthy K, Moreno V, Pearlman R, Song M, Tsilidis KK, Vodička P, Woods MO, Wu K, Hsu L, Gunter MJ, Peters U, Murphy N; Colorectal Transdisciplinary (CORECT) Study, the Colon Cancer Family Registry (CCFR), Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO). Laskar RS, et al. Among authors: mccarthy k. Ann Oncol. 2024 Jun;35(6):523-536. doi: 10.1016/j.annonc.2024.02.008. Epub 2024 Feb 24. Ann Oncol. 2024. PMID: 38408508 Free PMC article.
Mutations in PPIB (cyclophilin B) delay type I procollagen chain association and result in perinatal lethal to moderate osteogenesis imperfecta phenotypes.
Pyott SM, Schwarze U, Christiansen HE, Pepin MG, Leistritz DF, Dineen R, Harris C, Burton BK, Angle B, Kim K, Sussman MD, Weis M, Eyre DR, Russell DW, McCarthy KJ, Steiner RD, Byers PH. Pyott SM, et al. Among authors: mccarthy kj. Hum Mol Genet. 2011 Apr 15;20(8):1595-609. doi: 10.1093/hmg/ddr037. Epub 2011 Jan 31. Hum Mol Genet. 2011. PMID: 21282188 Free PMC article.
Early onset colorectal cancer.
Chambers AC, Merriel SWD, Beard G, Greer H, Messenger DE, McCarthy K. Chambers AC, et al. Among authors: mccarthy k. BMJ. 2025 Jun 9;389:e082452. doi: 10.1136/bmj-2024-082452. BMJ. 2025. PMID: 40490290 No abstract available.
Dysregulated Tricarboxylic Acid Cycle Metabolism Is Associated With Right Ventricular Maladaptation in Pulmonary Vascular Disease.
Rosen DT, Kolb TM, Mathai SC, Suresh K, Damico R, Hsu S, Tedford RJ, Hemnes AR, Leopold JA, Horn EM, Berman-Rosenzweig ES, Rischard F, Frantz RP, Erzurum SC, Beck GJ, Hill NS, Barnard J, Farha S, Grunig G, Jellis C, Kwon DH, Mehra R, Park MM, Tang WHW, Hassoun PM, Simpson CE; PVDOMICS Study Group *. Rosen DT, et al. J Am Heart Assoc. 2025 Jun 3;14(11):e041127. doi: 10.1161/JAHA.124.041127. Epub 2025 May 22. J Am Heart Assoc. 2025. PMID: 40401597 Free article.
1,583 results