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External validation of a digital pathology-based multimodal artificial intelligence-derived prognostic model in patients with advanced prostate cancer starting long-term androgen deprivation therapy: a post-hoc ancillary biomarker study of four phase 3 randomised controlled trials of the STAMPEDE platform protocol.
Parker CTA, Mendes L, Liu VYT, Grist E, Joun S, Yamashita R, Mitani A, Chen E, Parry MA, Sachdeva A, Murphy L, Huang HC, Griffin J, van der Wal D, Todorovic T, Lall S, Santos Vidal S, Goncalves M, Thakali S, Wingate A, Zakka L, Brown M, Wetterskog D, Amos CL, Atako NB, Jones RJ, Cross WR, Gillessen S, Parker CC; STAMPEDE collaborators; Berney DM, Tran PT, Spratt DE, Sydes MR, Parmar MKB, Clarke NW, Brown LC, Feng FY, Esteva A, James ND, Attard G. Parker CTA, et al. Among authors: brown lc. Lancet Digit Health. 2025 Jun 3:100885. doi: 10.1016/j.landig.2025.100885. Online ahead of print. Lancet Digit Health. 2025. PMID: 40467357 Free article.
Psychiatric Pharmacogenomic Testing: A Primer for Clinicians.
Brown LC, Zai G, Kennedy JL, Müller DJ, Tavakoli E, Bousman C, Maruf AA. Brown LC, et al. Psychiatr Clin North Am. 2025 Jun;48(2):257-264. doi: 10.1016/j.psc.2025.01.004. Epub 2025 Mar 4. Psychiatr Clin North Am. 2025. PMID: 40348416 Review.
Plasma AR Alterations and Timing of Intensified Hormone Treatment for Prostate Cancer: the STAMPEDE Phase 3 Randomized Clinical Trial.
Leone G, Orlando F, Dutey-Magni P, Vainauskas O, Grist E, Ciani Y, Lall S, Thakali S, Wingate A, Wetterskog D, Sachdeva A, Sydes MR, McPhail N, Sreenivasan T, O'Sullivan JM, Clarke NW, Parmar MKB, Brown LC, James ND, Demichelis F, Attard G; STAMPEDE collaborators. Leone G, et al. Among authors: brown lc. JAMA Oncol. 2025 Feb 27;11(4):426-9. doi: 10.1001/jamaoncol.2024.7051. Online ahead of print. JAMA Oncol. 2025. PMID: 40014335
Enzalutamide and Docetaxel in Combination With Androgen Deprivation for Men With Metastatic Hormone-Sensitive Prostate Cancer: ENZADA, a Phase II Trial.
Burgess EF, Grigg CM, Boselli D, Symanowski JT, Golshayan A, Graham DL, Osei-Boateng K, Gavini N, Zhu J, Brown LC, Norek S, Begic XJ, Raghavan D. Burgess EF, et al. Among authors: brown lc. Clin Genitourin Cancer. 2025 Apr;23(2):102302. doi: 10.1016/j.clgc.2025.102302. Epub 2025 Jan 8. Clin Genitourin Cancer. 2025. PMID: 39903972 Clinical Trial.
Genomic Characterization and Prognostic Significance of Human Epidermal Growth Factor Receptor 2-Low, Hormone Receptor-Positive, Early Breast Cancers From the BIG 1-98 and SOFT Clinical Trials.
Luen SJ, Brown LC, van Geelen CT, Savas P, Kammler R, Dell'Orto P, Biasi O, Coates AS, Gelber RD, Thürlimann B, Colleoni M, Fleming GF, Francis PA, Regan MM, Viale G, Loi S. Luen SJ, et al. Among authors: brown lc. JCO Precis Oncol. 2025 Jan;9:e2400599. doi: 10.1200/PO-24-00599. Epub 2025 Jan 24. JCO Precis Oncol. 2025. PMID: 39854658 Clinical Trial.
The Relationship Between Dietary and Supplemental omega-3 Highly Unsaturated Fatty Acid Intake, Blood and Tissue omega-3 Highly Unsaturated Fatty Acid Concentrations, and Colorectal Polyp Recurrence: A Secondary Analysis of the seAFOod Polyp Prevention Trial.
Sun G, Fuller H, Fenton H, Race AD, Downing A, Rees CJ, Brown LC, Loadman PM, Williams EA, Hull MA. Sun G, et al. Among authors: brown lc. J Nutr. 2025 Feb;155(2):549-558. doi: 10.1016/j.tjnut.2024.12.004. Epub 2024 Dec 13. J Nutr. 2025. PMID: 39675479 Free PMC article. Clinical Trial.
Pharmacogenomic insights in psychiatric care: uncovering novel actionability, allele-specific CYP2D6 copy number variation, and phenoconversion in 15,000 patients.
Patel JN, Morris SA, Torres R, Rhead B, Vlangos C, Mueller DJ, Brown LC, Lefkofsky H, Ali M, De La Vega FM, Barnes KC, Zoghbi A, Stanton JD, Badgeley MA. Patel JN, et al. Among authors: brown lc. Mol Psychiatry. 2024 Nov;29(11):3495-3502. doi: 10.1038/s41380-024-02588-4. Epub 2024 May 23. Mol Psychiatry. 2024. PMID: 38783055 Free PMC article.
237 results