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Convergent epigenetic evolution drives relapse in acute myeloid leukemia.
Nuno K, Azizi A, Koehnke T, Lareau C, Ediriwickrema A, Corces MR, Satpathy AT, Majeti R. Nuno K, et al. Among authors: azizi a. Elife. 2024 Apr 22;13:e93019. doi: 10.7554/eLife.93019. Elife. 2024. PMID: 38647535 Free PMC article.
These results demonstrate that epigenetic evolution is a feature of relapsed AML and that convergent epigenetic evolution can occur following treatment with induction chemotherapy. Acute myeloid leukemia (or AML for short) is a type of blood cancer characterized by …
These results demonstrate that epigenetic evolution is a feature of relapsed AML and that convergent epigenetic evolution can occur f …
The Cell Type-Specific 5hmC Landscape and Dynamics of Healthy Human Hematopoiesis and TET2-Mutant Preleukemia.
Nakauchi Y, Azizi A, Thomas D, Corces MR, Reinisch A, Sharma R, Cruz Hernandez D, Köhnke T, Karigane D, Fan A, Martinez-Krams D, Stafford M, Kaur S, Dutta R, Phan P, Ediriwickrema A, McCarthy E, Ning Y, Phillips T, Ellison CK, Guler GD, Bergamaschi A, Ku CJ, Levy S, Majeti R. Nakauchi Y, et al. Among authors: azizi a. Blood Cancer Discov. 2022 Jul 6;3(4):346-367. doi: 10.1158/2643-3230.BCD-21-0143. Blood Cancer Discov. 2022. PMID: 35532363 Free PMC article.
A single cell framework identifies functionally and molecularly distinct multipotent progenitors in adult human hematopoiesis.
Ediriwickrema A, Nakauchi Y, Fan AC, Köhnke T, Hu X, Luca BA, Kim Y, Ramakrishnan S, Nakamoto M, Karigane D, Linde MH, Azizi A, Newman AM, Gentles AJ, Majeti R. Ediriwickrema A, et al. Among authors: azizi a. bioRxiv [Preprint]. 2024 May 10:2024.05.07.592983. doi: 10.1101/2024.05.07.592983. bioRxiv. 2024. PMID: 38766031 Free PMC article. Preprint.
Atlas of clinically distinct cell states and ecosystems across human solid tumors.
Luca BA, Steen CB, Matusiak M, Azizi A, Varma S, Zhu C, Przybyl J, Espín-Pérez A, Diehn M, Alizadeh AA, van de Rijn M, Gentles AJ, Newman AM. Luca BA, et al. Among authors: azizi a. Cell. 2021 Oct 14;184(21):5482-5496.e28. doi: 10.1016/j.cell.2021.09.014. Epub 2021 Sep 30. Cell. 2021. PMID: 34597583 Free PMC article.
565 results