Ortlund EA - Search Results

1

Sexual dimorphism and the multi-omic response to exercise training in rat subcutaneous white adipose tissue.

Many GM, Sanford JA, Sagendorf TJ, Hou Z, Nigro P, Whytock KL, Amar D, Caputo T, Gay NR, Gaul DA, Hirshman MF, Jimenez-Morales D, Lindholm ME, Muehlbauer MJ, Vamvini M, Bergman BC, Fernández FM, Goodyear LJ, Hevener AL, Ortlund EA, Sparks LM, Xia A, Adkins JN, Bodine SC, Newgard CB, Schenk S; MoTrPAC Study Group. Many GM, et al. Among authors: ortlund ea. Nat Metab. 2024 May;6(5):963-979. doi: 10.1038/s42255-023-00959-9. Epub 2024 May 1. Nat Metab. 2024. PMID: 38693320 Free PMC article.

2

Enantiomer-specific activities of an LRH-1 and SF-1 dual agonist.

Mays SG, Stec J, Liu X, D'Agostino EH, Whitby RJ, Ortlund EA. Mays SG, et al. Among authors: ortlund ea. Sci Rep. 2020 Dec 17;10(1):22279. doi: 10.1038/s41598-020-79251-9. Sci Rep. 2020. PMID: 33335203 Free PMC article.

3

Aging. Lysosomal signaling molecules regulate longevity in Caenorhabditis elegans.

Folick A, Oakley HD, Yu Y, Armstrong EH, Kumari M, Sanor L, Moore DD, Ortlund EA, Zechner R, Wang MC. Folick A, et al. Among authors: ortlund ea. Science. 2015 Jan 2;347(6217):83-6. doi: 10.1126/science.1258857. Science. 2015. PMID: 25554789 Free PMC article.

4

Development of a new class of liver receptor homolog-1 (LRH-1) agonists by photoredox conjugate addition.

Cornelison JL, Cato ML, Johnson AM, D'Agostino EH, Melchers D, Patel AB, Mays SG, Houtman R, Ortlund EA, Jui NT. Cornelison JL, et al. Among authors: ortlund ea. Bioorg Med Chem Lett. 2020 Aug 15;30(16):127293. doi: 10.1016/j.bmcl.2020.127293. Epub 2020 May 30. Bioorg Med Chem Lett. 2020. PMID: 32631515 Free PMC article.

5

Disruption of a key ligand-H-bond network drives dissociative properties in vamorolone for Duchenne muscular dystrophy treatment.

Liu X, Wang Y, Gutierrez JS, Damsker JM, Nagaraju K, Hoffman EP, Ortlund EA. Liu X, et al. Among authors: ortlund ea. Proc Natl Acad Sci U S A. 2020 Sep 29;117(39):24285-24293. doi: 10.1073/pnas.2006890117. Epub 2020 Sep 11. Proc Natl Acad Sci U S A. 2020. PMID: 32917814 Free PMC article.

6

The lncRNA Growth Arrest Specific 5 Regulates Cell Survival via Distinct Structural Modules with Independent Functions.

Frank F, Kavousi N, Bountali A, Dammer EB, Mourtada-Maarabouni M, Ortlund EA. Frank F, et al. Among authors: ortlund ea. Cell Rep. 2020 Jul 21;32(3):107933. doi: 10.1016/j.celrep.2020.107933. Cell Rep. 2020. PMID: 32697996 Free article.

7

Structural basis for ligand regulation of the fatty acid-binding protein 5, peroxisome proliferator-activated receptor β/δ (FABP5-PPARβ/δ) signaling pathway.

Armstrong EH, Goswami D, Griffin PR, Noy N, Ortlund EA. Armstrong EH, et al. Among authors: ortlund ea. J Biol Chem. 2014 May 23;289(21):14941-54. doi: 10.1074/jbc.M113.514646. Epub 2014 Apr 1. J Biol Chem. 2014. PMID: 24692551 Free PMC article.

8

Structure and Dynamics of the Liver Receptor Homolog 1-PGC1α Complex.

Mays SG, Okafor CD, Tuntland ML, Whitby RJ, Dharmarajan V, Stec J, Griffin PR, Ortlund EA. Mays SG, et al. Among authors: ortlund ea. Mol Pharmacol. 2017 Jul;92(1):1-11. doi: 10.1124/mol.117.108514. Epub 2017 Mar 31. Mol Pharmacol. 2017. PMID: 28363985 Free PMC article.

9

High-resolution plasma metabolomics analysis to detect Mycobacterium tuberculosis-associated metabolites that distinguish active pulmonary tuberculosis in humans.

Collins JM, Walker DI, Jones DP, Tukvadze N, Liu KH, Tran VT, Uppal K, Frediani JK, Easley KA, Shenvi N, Khadka M, Ortlund EA, Kempker RR, Blumberg HM, Ziegler TR. Collins JM, et al. Among authors: ortlund ea. PLoS One. 2018 Oct 11;13(10):e0205398. doi: 10.1371/journal.pone.0205398. eCollection 2018. PLoS One. 2018. PMID: 30308073 Free PMC article.

10

Allosteric regulation of thioesterase superfamily member 1 by lipid sensor domain binding fatty acids and lysophosphatidylcholine.

Tillman MC, Imai N, Li Y, Khadka M, Okafor CD, Juneja P, Adhiyaman A, Hagen SJ, Cohen DE, Ortlund EA. Tillman MC, et al. Among authors: ortlund ea. Proc Natl Acad Sci U S A. 2020 Sep 8;117(36):22080-22089. doi: 10.1073/pnas.2003877117. Epub 2020 Aug 20. Proc Natl Acad Sci U S A. 2020. PMID: 32820071 Free PMC article.

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