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342 results

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Page 1
BTK drives neutrophil activation for sterilizing antifungal immunity.
Desai JV, Zarakas MA, Wishart AL, Roschewski M, Aufiero MA, Donkò A, Wigerblad G, Shlezinger N, Plate M, James MR, Lim JK, Uzel G, Bergerson JR, Fuss I, Cramer RA, Franco LM, Clark ES, Khan WN, Yamanaka D, Chamilos G, El-Benna J, Kaplan MJ, Staudt LM, Leto TL, Holland SM, Wilson WH, Hohl TM, Lionakis MS. Desai JV, et al. Among authors: staudt lm. J Clin Invest. 2024 May 2;134(12):e176142. doi: 10.1172/JCI176142. J Clin Invest. 2024. PMID: 38696257 Free PMC article.
Multi-Component, Time-Course screening to develop combination cancer therapies based on synergistic toxicity.
Ceribelli M, Tosto FA, Zhang X, Melani CJ, Roschewski M, Beck E, Klumpp-Thomas C, Peer CJ, Wilson KM, Chen L, McKnight C, Michael S, Itkin Z, Shinn P, Figg WD Sr, Wilson WH, Staudt LM, Thomas CJ. Ceribelli M, et al. Among authors: staudt lm. Proc Natl Acad Sci U S A. 2024 Dec 3;121(49):e2413372121. doi: 10.1073/pnas.2413372121. Epub 2024 Nov 25. Proc Natl Acad Sci U S A. 2024. PMID: 39585996 Free PMC article.
A phase 1 study of interleukin-15 in combination with mogamulizumab in relapsed and refractory T-cell malignancies.
Gordon MJ, Dubois S, Miljkovic MD, Ng S, Bryant B, Lakhotia R, Melani C, Pittaluga S, Conlon K, Waldmann T, Staudt LM, Wilson WH, Roschewski M. Gordon MJ, et al. Among authors: staudt lm. Blood Neoplasia. 2024 Nov 2;2(1):100054. doi: 10.1016/j.bneo.2024.100054. eCollection 2025 Feb. Blood Neoplasia. 2024. PMID: 40546724 Free PMC article. Clinical Trial.
Multi-omic profiling of follicular lymphoma reveals changes in tissue architecture and enhanced stromal remodeling in high-risk patients.
Radtke AJ, Postovalova E, Varlamova A, Bagaev A, Sorokina M, Kudryashova O, Meerson M, Polyakova M, Galkin I, Svekolkin V, Isaev S, Wiebe D, Sharun A, Sarachakov A, Perelman G, Lozinsky Y, Yaniv Z, Lowekamp BC, Speranza E, Yao L, Pittaluga S, Shaffer AL 3rd, Jonigk D, Phelan JD, Davies-Hill T, Huang DW, Ovcharov P, Nomie K, Nuzhdina E, Kotlov N, Ataullakhanov R, Fowler N, Kelly M, Muppidi J, Davis JL, Hernandez JM, Wilson WH, Jaffe ES, Staudt LM, Roschewski M, Germain RN. Radtke AJ, et al. Among authors: staudt lm. Cancer Cell. 2024 Mar 11;42(3):444-463.e10. doi: 10.1016/j.ccell.2024.02.001. Epub 2024 Feb 29. Cancer Cell. 2024. PMID: 38428410 Free PMC article.
Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomas.
Choi J, Ceribelli M, Phelan JD, Häupl B, Huang DW, Wright GW, Hsiao T, Morris V, Ciccarese F, Wang B, Corcoran S, Scheich S, Yu X, Xu W, Yang Y, Zhao H, Zhou J, Zhang G, Muppidi J, Inghirami GG, Oellerich T, Wilson WH, Thomas CJ, Staudt LM. Choi J, et al. Among authors: staudt lm. Cancer Cell. 2024 May 13;42(5):833-849.e12. doi: 10.1016/j.ccell.2024.04.007. Epub 2024 May 2. Cancer Cell. 2024. PMID: 38701792 Free PMC article.
Combination Targeted Therapy in Relapsed Diffuse Large B-Cell Lymphoma.
Melani C, Lakhotia R, Pittaluga S, Phelan JD, Huang DW, Wright G, Simard J, Muppidi J, Thomas CJ, Ceribelli M, Tosto FA, Yang Y, Xu W, Davies-Hill T, Pack SD, Peer CJ, Arisa O, Mena E, Lindenberg L, Bergvall E, Portell CA, Farah RJ, Lee ST, Pradhan A, Morrison C, Tadese A, Juanitez AM, Lu C, Jacob A, Simmons H, Figg WD, Steinberg SM, Jaffe ES, Roschewski M, Staudt LM, Wilson WH. Melani C, et al. Among authors: staudt lm. N Engl J Med. 2024 Jun 20;390(23):2143-2155. doi: 10.1056/NEJMoa2401532. N Engl J Med. 2024. PMID: 38899693 Free PMC article. Clinical Trial.
Response to Bruton's tyrosine kinase inhibitors in aggressive lymphomas linked to chronic selective autophagy.
Phelan JD, Scheich S, Choi J, Wright GW, Häupl B, Young RM, Rieke SA, Pape M, Ji Y, Urlaub H, Bolomsky A, Doebele C, Zindel A, Wotapek T, Kasbekar M, Collinge B, Huang DW, Coulibaly ZA, Morris VM, Zhuang X, Enssle JC, Yu X, Xu W, Yang Y, Zhao H, Wang Z, Tran AD, Shoemaker CJ, Shevchenko G, Hodson DJ, Shaffer AL 3rd, Staudt LM, Oellerich T. Phelan JD, et al. Among authors: staudt lm. Cancer Cell. 2024 Feb 12;42(2):238-252.e9. doi: 10.1016/j.ccell.2023.12.019. Epub 2024 Jan 11. Cancer Cell. 2024. PMID: 38215749 Free PMC article.
342 results