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The peroxisomal fatty acid transporter ABCD1/PMP-4 is required in the C. elegans hypodermis for axonal maintenance: A worm model for adrenoleukodystrophy.
Coppa A, Guha S, Fourcade S, Parameswaran J, Ruiz M, Moser AB, Schlüter A, Murphy MP, Lizcano JM, Miranda-Vizuete A, Dalfó E, Pujol A. Coppa A, et al. Among authors: parameswaran j. Free Radic Biol Med. 2020 May 20;152:797-809. doi: 10.1016/j.freeradbiomed.2020.01.177. Epub 2020 Feb 1. Free Radic Biol Med. 2020. PMID: 32017990 Free PMC article.
Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance.
Fourcade S, Morató L, Parameswaran J, Ruiz M, Ruiz-Cortés T, Jové M, Naudí A, Martínez-Redondo P, Dierssen M, Ferrer I, Villarroya F, Pamplona R, Vaquero A, Portero-Otín M, Pujol A. Fourcade S, et al. Among authors: parameswaran j. Aging Cell. 2017 Dec;16(6):1404-1413. doi: 10.1111/acel.12682. Epub 2017 Oct 5. Aging Cell. 2017. PMID: 28984064 Free PMC article.
Rare variants in MYH15 modify amyotrophic lateral sclerosis risk.
Kim H, Lim J, Bao H, Jiao B, Canon SM, Epstein MP, Xu K, Jiang J, Parameswaran J, Li Y, Moberg KH, Landers JE, Fournier C, Allen EG, Glass JD, Wingo TS, Jin P. Kim H, et al. Among authors: parameswaran j. Hum Mol Genet. 2019 Jul 15;28(14):2309-2318. doi: 10.1093/hmg/ddz063. Hum Mol Genet. 2019. PMID: 30985904 Free PMC article.
Patient-Specific iPSC-Derived Astrocytes Contribute to Non-Cell-Autonomous Neurodegeneration in Parkinson's Disease.
di Domenico A, Carola G, Calatayud C, Pons-Espinal M, Muñoz JP, Richaud-Patin Y, Fernandez-Carasa I, Gut M, Faella A, Parameswaran J, Soriano J, Ferrer I, Tolosa E, Zorzano A, Cuervo AM, Raya A, Consiglio A. di Domenico A, et al. Among authors: parameswaran j. Stem Cell Reports. 2019 Feb 12;12(2):213-229. doi: 10.1016/j.stemcr.2018.12.011. Epub 2019 Jan 10. Stem Cell Reports. 2019. PMID: 30639209 Free PMC article.
RNA-mediated toxicity in C9orf72 ALS and FTD.
McEachin ZT, Parameswaran J, Raj N, Bassell GJ, Jiang J. McEachin ZT, et al. Among authors: parameswaran j. Neurobiol Dis. 2020 Nov;145:105055. doi: 10.1016/j.nbd.2020.105055. Epub 2020 Aug 21. Neurobiol Dis. 2020. PMID: 32829028 Free PMC article. Review.
Vepdegestrant, a PROTAC Estrogen Receptor Degrader, in Advanced Breast Cancer.
Campone M, De Laurentiis M, Jhaveri K, Hu X, Ladoire S, Patsouris A, Zamagni C, Cui J, Cazzaniga M, Cil T, Jerzak KJ, Fuentes C, Yoshinami T, Rodriguez-Lescure A, Sezer A, Fontana A, Guarneri V, Molckovsky A, Mouret-Reynier MA, Demirci U, Zhang Y, Valota O, Lu DR, Martignoni M, Parameswaran J, Zhi X, Hamilton EP; VERITAC-2 Study Group. Campone M, et al. Among authors: parameswaran j. N Engl J Med. 2025 May 31. doi: 10.1056/NEJMoa2505725. Online ahead of print. N Engl J Med. 2025. PMID: 40454645
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