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Page 1
Targeting Acute Myeloid Leukemia Stem Cells through Perturbation of Mitochondrial Calcium.
Sheth AI, Althoff MJ, Tolison H, Engel K, Amaya ML, Krug AE, Young TN, Minhajuddin M, Pei S, Patel SB, Winters A, Miller R, Shelton IT, St-Germain J, Ling T, Jones CL, Raught B, Gillen AE, Ransom M, Staggs S, Smith CA, Pollyea DA, Stevens BM, Jordan CT. Sheth AI, et al. Among authors: shelton it. Cancer Discov. 2024 Oct 4;14(10):1922-1939. doi: 10.1158/2159-8290.CD-23-1145. Cancer Discov. 2024. PMID: 38787341 Free PMC article.
A Novel Type of Monocytic Leukemia Stem Cell Revealed by the Clinical Use of Venetoclax-Based Therapy.
Pei S, Shelton IT, Gillen AE, Stevens BM, Gasparetto M, Wang Y, Liu L, Liu J, Brunetti TM, Engel K, Staggs S, Showers W, Sheth AI, Amaya ML, Minhajuddin M, Winters A, Patel SB, Tolison H, Krug AE, Young TN, Schowinsky J, McMahon CM, Smith CA, Pollyea DA, Jordan CT. Pei S, et al. Among authors: shelton it. Cancer Discov. 2023 Sep 6;13(9):2032-2049. doi: 10.1158/2159-8290.CD-22-1297. Cancer Discov. 2023. PMID: 37358260 Free PMC article.
Targeting Acute Myeloid Leukemia Stem Cells Through Perturbation of Mitochondrial Calcium.
Sheth AI, Engel K, Tolison H, Althoff MJ, Amaya ML, Krug A, Young T, Pei S, Patel SB, Minhajuddin M, Winters A, Miller R, Shelton I, St-Germain J, Ling T, Jones C, Raught B, Gillen A, Ransom M, Staggs S, Smith CA, Pollyea DA, Stevens BM, Jordan CT. Sheth AI, et al. bioRxiv [Preprint]. 2023 Oct 3:2023.10.02.560330. doi: 10.1101/2023.10.02.560330. bioRxiv. 2023. Update in: Cancer Discov. 2024 Oct 4;14(10):1922-1939. doi: 10.1158/2159-8290.CD-23-1145. PMID: 37873284 Free PMC article. Updated. Preprint.
Therapy resistance in AML is mediated by cytoplasmic sequestration of the transcriptional repressor IRF2BP2.
Althoff MJ, Minhajuddin M, Stevens BM, Gillen AE, Gipson S, Patel SB, Shelton IT, Miller R, Vujovic A, Krug A, Young T, Showers WM, Dzieciatkowska M, Stephenson D, Tyagi A, Ellegast JM, Wright T, Stegmaier K, Opferman JT, D'Alessandro A, Smith CA, Jordan CT. Althoff MJ, et al. Among authors: shelton it. bioRxiv [Preprint]. 2025 May 24:2025.05.22.655396. doi: 10.1101/2025.05.22.655396. bioRxiv. 2025. PMID: 40475530 Free PMC article. Preprint.