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Page 1
Immunotherapy-related cognitive impairment after CAR T cell therapy in mice.
Geraghty AC, Acosta-Alvarez L, Rotiroti MC, Dutton S, O'Dea MR, Kim W, Trivedi V, Mancusi R, Shamardani K, Malacon K, Woo PJ, Martinez-Velez N, Pham T, Reche-Ley NN, Otubu G, Castenada EH, Nwangwu K, Xu H, Mulinyawe SB, Zamler DB, Ni L, Cross K, Rustenhoven J, Kipnis J, Liddelow SA, Mackall CL, Majzner RG, Monje M. Geraghty AC, et al. Among authors: rustenhoven j. Cell. 2025 Jun 12;188(12):3238-3258.e25. doi: 10.1016/j.cell.2025.03.041. Epub 2025 May 12. Cell. 2025. PMID: 40359942 Free article.
In vitro models of microglia: a comparative study.
Woolf Z, Stevenson TJ, Lee K, Highet B, Macapagal Foliaki J, Ratiu R, Rustenhoven J, Correia J, Schweder P, Heppner P, Weinert M, Coppieters N, Park T, Montgomery J, Smith AM, Dragunow M. Woolf Z, et al. Among authors: rustenhoven j. Sci Rep. 2025 May 5;15(1):15621. doi: 10.1038/s41598-025-99867-z. Sci Rep. 2025. PMID: 40320508 Free PMC article.
Age-related meningeal extracellular matrix remodeling compromises CNS lymphatic function.
Hitpass Romero K, Stevenson TJ, Smyth LCD, Watkin B, McCullough SJC, Vinnell L, Smith AM, Schweder P, Correia JA, Kipnis J, Dragunow M, Rustenhoven J. Hitpass Romero K, et al. Among authors: rustenhoven j. J Neuroinflammation. 2025 Apr 17;22(1):109. doi: 10.1186/s12974-025-03436-0. J Neuroinflammation. 2025. PMID: 40247257 Free PMC article.
Engineered T cell therapy for central nervous system injury.
Gao W, Kim MW, Dykstra T, Du S, Boskovic P, Lichti CF, Ruiz-Cardozo MA, Gu X, Weizman Shapira T, Rustenhoven J, Molina C, Smirnov I, Merbl Y, Ray WZ, Kipnis J. Gao W, et al. Among authors: rustenhoven j. Nature. 2024 Oct;634(8034):693-701. doi: 10.1038/s41586-024-07906-y. Epub 2024 Sep 4. Nature. 2024. PMID: 39232158
Brain-Engrafted Monocyte-derived Macrophages from Blood and Skull-Bone Marrow Exhibit Distinct Identities from Microglia.
Du S, Drieu A, Cheng Y, Storck SE, Rustenhoven J, Mamuladze T, Bhattarai B, Brioschi S, Nguyen K, Ou F, Cao J, Rodrigues PF, Smirnov I, DeNardo D, Ginhoux F, Cella M, Colonna M, Kipnis J. Du S, et al. Among authors: rustenhoven j. bioRxiv [Preprint]. 2024 Aug 9:2024.08.08.606900. doi: 10.1101/2024.08.08.606900. bioRxiv. 2024. PMID: 39211090 Free PMC article. Preprint.
An inducible genetic tool to track and manipulate specific microglial states reveals their plasticity and roles in remyelination.
Barclay KM, Abduljawad N, Cheng Z, Kim MW, Zhou L, Yang J, Rustenhoven J, Mazzitelli JA, Smyth LCD, Kapadia D, Brioschi S, Beatty W, Hou J, Saligrama N, Colonna M, Yu G, Kipnis J, Li Q. Barclay KM, et al. Among authors: rustenhoven j. Immunity. 2024 Jun 11;57(6):1394-1412.e8. doi: 10.1016/j.immuni.2024.05.005. Epub 2024 May 30. Immunity. 2024. PMID: 38821054 Free PMC article.
Identification of direct connections between the dura and the brain.
Smyth LCD, Xu D, Okar SV, Dykstra T, Rustenhoven J, Papadopoulos Z, Bhasiin K, Kim MW, Drieu A, Mamuladze T, Blackburn S, Gu X, Gaitán MI, Nair G, Storck SE, Du S, White MA, Bayguinov P, Smirnov I, Dikranian K, Reich DS, Kipnis J. Smyth LCD, et al. Among authors: rustenhoven j. Nature. 2024 Mar;627(8002):165-173. doi: 10.1038/s41586-023-06993-7. Epub 2024 Feb 7. Nature. 2024. PMID: 38326613 Free PMC article.
Skull bone marrow channels as immune gateways to the central nervous system.
Mazzitelli JA, Pulous FE, Smyth LCD, Kaya Z, Rustenhoven J, Moskowitz MA, Kipnis J, Nahrendorf M. Mazzitelli JA, et al. Among authors: rustenhoven j. Nat Neurosci. 2023 Dec;26(12):2052-2062. doi: 10.1038/s41593-023-01487-1. Epub 2023 Nov 23. Nat Neurosci. 2023. PMID: 37996526 Free PMC article. Review.
48 results