Denomme N - Search Results

1

N-(4-Bromo-2,5-Dimethoxyphenethyl)-6-(4-Phenylbutoxy)Hexan-1-Amine (XOB): A Novel Phenylalkylamine Antagonist of Serotonin 2A Receptors and Voltage-Gated Sodium Channels.

Denomme N, Hernandez CC, Bock HA, Ohana RF, Bakshi S, Sherwood AM, McCorvy JD, Daley PF, Callaway WB, Hull JM, Alt A, Isom LL, Cozzi NV. Denomme N, et al. Mol Pharmacol. 2024 Jul 17;106(2):92-106. doi: 10.1124/molpharm.123.000837. Mol Pharmacol. 2024. PMID: 38821630

2

Biocatalytic Detoxification of Paralytic Shellfish Toxins.

Lukowski AL, Denomme N, Hinze ME, Hall S, Isom LL, Narayan ARH. Lukowski AL, et al. Among authors: denomme n. ACS Chem Biol. 2019 May 17;14(5):941-948. doi: 10.1021/acschembio.9b00123. Epub 2019 Apr 15. ACS Chem Biol. 2019. PMID: 30983320 Free PMC article.

3

Role of Voltage-Gated Sodium Channels in the Mechanism of Ether-Induced Unconsciousness.

Denomme N, Hull JM, Mashour GA. Denomme N, et al. Pharmacol Rev. 2019 Oct;71(4):450-466. doi: 10.1124/pr.118.016592. Pharmacol Rev. 2019. PMID: 31471460 Free article. Review.

4

The voltage-gated sodium channel inhibitor, 4,9-anhydrotetrodotoxin, blocks human Na_v1.1 in addition to Na_v1.6.

Denomme N, Lukowski AL, Hull JM, Jameson MB, Bouza AA, Narayan ARH, Isom LL. Denomme N, et al. Neurosci Lett. 2020 Apr 17;724:134853. doi: 10.1016/j.neulet.2020.134853. Epub 2020 Feb 27. Neurosci Lett. 2020. PMID: 32114117 Free PMC article.

5

Excitatory and inhibitory neuron defects in a mouse model of Scn1b-linked EIEE52.

Hull JM, O'Malley HA, Chen C, Yuan Y, Denomme N, Bouza AA, Anumonwo C, Lopez-Santiago LF, Isom LL. Hull JM, et al. Among authors: denomme n. Ann Clin Transl Neurol. 2020 Nov;7(11):2137-2149. doi: 10.1002/acn3.51205. Epub 2020 Sep 26. Ann Clin Transl Neurol. 2020. PMID: 32979291 Free PMC article.

6

Heterogeneity of voltage gated sodium current density between neurons decorrelates spiking and suppresses network synchronization in Scn1b null mouse models.

Hull JM, Denomme N, Yuan Y, Booth V, Isom LL. Hull JM, et al. Among authors: denomme n. Sci Rep. 2023 Jun 1;13(1):8887. doi: 10.1038/s41598-023-36036-0. Sci Rep. 2023. PMID: 37264112 Free PMC article.

7

Antisense oligonucleotides restore excitability, GABA signalling and sodium current density in a Dravet syndrome model.

Yuan Y, Lopez-Santiago L, Denomme N, Chen C, O'Malley HA, Hodges SL, Ji S, Han Z, Christiansen A, Isom LL. Yuan Y, et al. Among authors: denomme n. Brain. 2024 Apr 4;147(4):1231-1246. doi: 10.1093/brain/awad349. Brain. 2024. PMID: 37812817 Free PMC article.

8

Neuromodulation of voltage-gated sodium channels by Gβ1γ2 subunits: Implications for GNB1-linked encephalopathy.

Denomme N, Hodges SL, Lopez-Santiago L, Yuan Y, Ziobro JM, Minton J, Chen C, Chen Y, Hull JM, Offord J, Smrcka AV, Isom LL. Denomme N, et al. Neurobiol Dis. 2025 Jun 5;213:106990. doi: 10.1016/j.nbd.2025.106990. Online ahead of print. Neurobiol Dis. 2025. PMID: 40482731 Free article.

9

The Domino Effect: Ed Domino's early studies of Psychoactive Drugs.

Denomme N BS. Denomme N BS. Among authors: denomme n b s. J Psychoactive Drugs. 2018 Sep-Oct;50(4):298-305. doi: 10.1080/02791072.2018.1506599. Epub 2018 Aug 15. J Psychoactive Drugs. 2018. PMID: 30111247 Review.

10

Ketamine, the First Associative Anesthetic? Some Considerations on Classifying Psychedelics, Entactogens, and Dissociatives.

Denomme N, Heifets BD. Denomme N, et al. Am J Psychiatry. 2024 Sep 1;181(9):784-786. doi: 10.1176/appi.ajp.20240644. Am J Psychiatry. 2024. PMID: 39217435 No abstract available.

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