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Sirtuin E deacetylase is required for full virulence of Aspergillus fumigatus.
Wassano NS, da Silva GB, Reis AH, A Gerhardt J, Antoniel EP, Akiyama D, Rezende CP, Neves LX, Vasconcelos EJR, de Figueiredo FL, Almeida F, de Castro PA, Pinzan CF, Goldman GH, Paes Leme AF, Fill TP, Moretti NS, Damasio A. Wassano NS, et al. Among authors: vasconcelos ejr. Commun Biol. 2024 Jun 8;7(1):704. doi: 10.1038/s42003-024-06383-3. Commun Biol. 2024. PMID: 38851817 Free PMC article.
Protein acetylation in the critical biological processes in protozoan parasites.
Maran SR, Fleck K, Monteiro-Teles NM, Isebe T, Walrad P, Jeffers V, Cestari I, Vasconcelos EJR, Moretti N. Maran SR, et al. Among authors: vasconcelos ejr. Trends Parasitol. 2021 Sep;37(9):815-830. doi: 10.1016/j.pt.2021.04.008. Epub 2021 May 12. Trends Parasitol. 2021. PMID: 33994102 Free PMC article. Review.
Deacetylation by sirtuins is important for Aspergillus fumigatus pathogenesis and virulence.
Wassano NS, da Silva GB, Reis AH, Gerhardt JA, Antoniel EP, Akiyama D, Rezende CP, Neves LX, Vasconcelos E, Figueiredo FL, Almeida F, de Castro PA, Pinzan CF, Goldman GH, Leme AFP, Fill TP, Moretti NS, Damasio A. Wassano NS, et al. bioRxiv [Preprint]. 2023 Sep 25:2023.09.25.558961. doi: 10.1101/2023.09.25.558961. bioRxiv. 2023. PMID: 37808717 Free PMC article. Preprint.
Inhibition of histone methyltransferase EZH2 in Schistosoma mansoni in vitro by GSK343 reduces egg laying and decreases the expression of genes implicated in DNA replication and noncoding RNA metabolism.
Pereira ASA, Amaral MS, Vasconcelos EJR, Pires DS, Asif H, daSilva LF, Morales-Vicente DA, Carneiro VC, Angeli CB, Palmisano G, Fantappie MR, Pierce RJ, Setubal JC, Verjovski-Almeida S. Pereira ASA, et al. Among authors: vasconcelos ejr. PLoS Negl Trop Dis. 2018 Oct 26;12(10):e0006873. doi: 10.1371/journal.pntd.0006873. eCollection 2018 Oct. PLoS Negl Trop Dis. 2018. PMID: 30365505 Free PMC article.
PRPF8-mediated dysregulation of hBrr2 helicase disrupts human spliceosome kinetics and 5´-splice-site selection causing tissue-specific defects.
Atkinson R, Georgiou M, Yang C, Szymanska K, Lahat A, Vasconcelos EJR, Ji Y, Moya Molina M, Collin J, Queen R, Dorgau B, Watson A, Kurzawa-Akanbi M, Laws R, Saxena A, Shyan Beh C, Siachisumo C, Goertler F, Karwatka M, Davey T, Inglehearn CF, McKibbin M, Lührmann R, Steel DH, Elliott DJ, Armstrong L, Urlaub H, Ali RR, Grellscheid SN, Johnson CA, Mozaffari-Jovin S, Lako M. Atkinson R, et al. Among authors: vasconcelos ejr. Nat Commun. 2024 Apr 11;15(1):3138. doi: 10.1038/s41467-024-47253-0. Nat Commun. 2024. PMID: 38605034 Free PMC article.
Specialized ribosomes: integrating new insights and current challenges.
Beavan AJS, Thuburn V, Fatkhullin B, Cunningham J, Hopes TS, Dimascio E, Chan T, Zhao N, Norris K, Chau C, Vasconcelos EJR, Wood A, Whitehouse A, Actis P, Davies B, Fontana J, O'Connell MJ, Thomson E, Aspden JL. Beavan AJS, et al. Among authors: vasconcelos ejr. Philos Trans R Soc Lond B Biol Sci. 2025 Mar 6;380(1921):20230377. doi: 10.1098/rstb.2023.0377. Epub 2025 Mar 6. Philos Trans R Soc Lond B Biol Sci. 2025. PMID: 40045788 Free PMC article. Review.
44 results