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Page 1
Methylome-wide studies of six metabolic traits.
Smith HM, Ng HK, Moodie JE, Gadd DA, McCartney DL, Bernabeu E, Campbell A, Redmond P, Taylor A, Page D, Corley J, Harris SE, Tay D, Deary IJ, Evans KL, Robinson MR, Chambers JC, Loh M, Cox SR, Marioni RE, Hillary RF. Smith HM, et al. Among authors: chambers jc. medRxiv [Preprint]. 2024 May 29:2024.05.29.24308103. doi: 10.1101/2024.05.29.24308103. medRxiv. 2024. PMID: 38853823 Free PMC article. Preprint.
Blood-based epigenome-wide analyses of chronic low-grade inflammation across diverse population cohorts.
Hillary RF, Ng HK, McCartney DL, Elliott HR, Walker RM, Campbell A, Huang F, Direk K, Welsh P, Sattar N, Corley J, Hayward C, McIntosh AM, Sudlow C, Evans KL, Cox SR, Chambers JC, Loh M, Relton CL, Marioni RE, Yousefi PD, Suderman M. Hillary RF, et al. Among authors: chambers jc. Cell Genom. 2024 May 8;4(5):100544. doi: 10.1016/j.xgen.2024.100544. Epub 2024 Apr 30. Cell Genom. 2024. PMID: 38692281 Free PMC article.
Adiposity and metabolic health in Asian populations: an epidemiological study using dual-energy x-ray absorptiometry in Singapore.
Mina T, Xie W, Low DY, Wang X, Lam BCC, Sadhu N, Ng HK, Aziz NA, Tong TYY, Kerk SK, Choo WL, Low GL, Ibrahim H, Lim L, Tai ES, Wansaicheong G, Dalan R, Yew YW, Elliott P, Riboli E, Loh M, Ngeow J, Lee ES, Lee J, Best J, Chambers J. Mina T, et al. Lancet Diabetes Endocrinol. 2024 Oct;12(10):704-715. doi: 10.1016/S2213-8587(24)00195-5. Epub 2024 Aug 29. Lancet Diabetes Endocrinol. 2024. PMID: 39217997
The relationships between sleep and adiposity amongst multi-ethnic Asian populations: a cross-sectional analysis of the Health for Life in Singapore (HELIOS) study.
Lam CCB, Mina T, Xie W, Low YD, Yew YW, Wang X, Riboli E, Elliott P, Lee J, Ngeow J, Lee ES, Loh M, Chambers JC. Lam CCB, et al. Among authors: chambers jc. Int J Obes (Lond). 2025 Apr;49(4):596-604. doi: 10.1038/s41366-024-01666-5. Epub 2024 Nov 19. Int J Obes (Lond). 2025. PMID: 39562689 Free PMC article.
DNA methylation-based predictors of metabolic traits in Scottish and Singaporean cohorts.
Smith HM, Ng HK, Moodie JE, Gadd DA, McCartney DL, Bernabeu E, Campbell A, Redmond P, Taylor A, Page D, Corley J, Harris SE, Tay D, Deary IJ, Evans KL, Robinson MR, Chambers JC, Loh M, Cox SR, Marioni RE, Hillary RF. Smith HM, et al. Among authors: chambers jc. Am J Hum Genet. 2025 Jan 2;112(1):106-115. doi: 10.1016/j.ajhg.2024.11.012. Epub 2024 Dec 19. Am J Hum Genet. 2025. PMID: 39706196 Free PMC article.
Nuclear regulatory disturbances precede and predict the development of Type-2 diabetes in Asian populations.
Jain PR, Ng HK, Tay D, Mina T, Low D, Sadhu N, Kooner IK, Gupta A, Li TF, Bertin N, Chin CWL, Fang CJ, Goh LL, Mok SQ, Peh SQ, Sabanayagam C, Jha V, Kasturiratne A, Katulanda P, Khawaja KI, Lim WK, Leong KP, Cheng CY, Yuan JM, Elliott P, Riboli E, Sing LE, Lee J, Ngeow J, Liu JJ, Best J, Kooner JS, Tai ES, Tan P, van Dam RM, Koh WP, Xueling S, Loh M, Chambers JC. Jain PR, et al. Among authors: chambers jc. medRxiv [Preprint]. 2025 Feb 14:2025.02.14.25322264. doi: 10.1101/2025.02.14.25322264. medRxiv. 2025. PMID: 39990582 Free PMC article. Preprint.
Single-cell RNA sequencing of peripheral blood links cell-type-specific regulation of splicing to autoimmune and inflammatory diseases.
Tian C, Zhang Y, Tong Y, Kock KH, Sim DY, Liu F, Dong J, Jing Z, Wang W, Gao J, Tan LM, Han KY, Tomofuji Y, Nakano M, Buyamin EV, Sonthalia R, Ando Y, Hatano H, Sonehara K; Asian Immune Diversity Atlas Network; Jin X, Loh M, Chambers J, Hon CC, Choi M, Park JE, Ishigaki K, Okamura T, Fujio K, Okada Y, Park WY, Shin JW, Roca X, Prabhakar S, Liu B. Tian C, et al. Nat Genet. 2024 Dec;56(12):2739-2752. doi: 10.1038/s41588-024-02019-8. Epub 2024 Dec 3. Nat Genet. 2024. PMID: 39627432 Free PMC article.
Risk prediction models for type 2 diabetes using either fasting plasma glucose or HbA1c in Chinese, Malay, and Indians: Results from three multi-ethnic Singapore cohorts.
Seah JYH, Yao J, Hong Y, Lim CGY, Sabanayagam C, Nusinovici S, Gardner DS, Loh M, Müller-Riemenschneider F, Tan CS, Yeo KK, Wong TY, Cheng CY, Ma S, Tai ES, Chambers JC, van Dam RM, Sim X. Seah JYH, et al. Among authors: chambers jc. Diabetes Res Clin Pract. 2023 Sep;203:110878. doi: 10.1016/j.diabres.2023.110878. Epub 2023 Aug 15. Diabetes Res Clin Pract. 2023. PMID: 37591346
318 results