Migaud ME - Search Results

1

Oncometabolite 2-hydroxyglutarate suppresses basal protein levels of DNA polymerase beta that enhances alkylating agent and PARG inhibition induced cytotoxicity.

Saville KM, Al-Rahahleh RQ, Siddiqui AH, Andrews ME, Roos WP, Koczor CA, Andrews JF, Hayat F, Migaud ME, Sobol RW. Saville KM, et al. Among authors: migaud me. DNA Repair (Amst). 2024 Aug;140:103700. doi: 10.1016/j.dnarep.2024.103700. Epub 2024 Jun 4. DNA Repair (Amst). 2024. PMID: 38897003 Free article.

2

NAD precursors cycle between host tissues and the gut microbiome.

Chellappa K, McReynolds MR, Lu W, Zeng X, Makarov M, Hayat F, Mukherjee S, Bhat YR, Lingala SR, Shima RT, Descamps HC, Cox T, Ji L, Jankowski C, Chu Q, Davidson SM, Thaiss CA, Migaud ME, Rabinowitz JD, Baur JA. Chellappa K, et al. Among authors: migaud me. Cell Metab. 2022 Dec 6;34(12):1947-1959.e5. doi: 10.1016/j.cmet.2022.11.004. Cell Metab. 2022. PMID: 36476934 Free PMC article.

3

Dihydroxyacetone suppresses mTOR nutrient signaling and induces mitochondrial stress in liver cells.

Hernandez A, Sonavane M, Smith KR, Seiger J, Migaud ME, Gassman NR. Hernandez A, et al. Among authors: migaud me. PLoS One. 2022 Dec 6;17(12):e0278516. doi: 10.1371/journal.pone.0278516. eCollection 2022. PLoS One. 2022. PMID: 36472985 Free PMC article.

4

A tipping point in dihydroxyacetone exposure: mitochondrial stress and metabolic reprogramming alter survival in rat cardiomyocytes H9c2 cells.

Hernandez A, Belfleur L, Migaud M, Gassman NR. Hernandez A, et al. Chem Biol Interact. 2024 May 1;394:110991. doi: 10.1016/j.cbi.2024.110991. Epub 2024 Apr 4. Chem Biol Interact. 2024. PMID: 38582340 Free PMC article.

5

Editorial: NAD+ metabolism as a novel target against infection-Volume II.

Balducci E, Braidy N, Migaud M. Balducci E, et al. Front Mol Biosci. 2022 Nov 21;9:1087897. doi: 10.3389/fmolb.2022.1087897. eCollection 2022. Front Mol Biosci. 2022. PMID: 36479384 Free PMC article. No abstract available.

6

The NADase CD38 is a central regulator in gouty inflammation and a novel druggable therapeutic target.

Alabarse PG, Oliveira P, Qin H, Yan T, Migaud M, Terkeltaub R, Liu-Bryan R. Alabarse PG, et al. Inflamm Res. 2024 May;73(5):739-751. doi: 10.1007/s00011-024-01863-y. Epub 2024 Mar 16. Inflamm Res. 2024. PMID: 38493256 Free PMC article.

7

Dysregulated nicotinamide adenine dinucleotide metabolome in patients hospitalized with COVID-19.

Valderrábano RJ, Wipper B, Pencina KM, Migaud M, Shang YV, Latham NK, Montano M, Cunningham JM, Wilson L, Peng L, Memish-Beleva Y, Bhargava A, Swain PM, Lehman P, Lavu S, Livingston DJ, Bhasin S. Valderrábano RJ, et al. Aging Cell. 2024 Dec;23(12):e14326. doi: 10.1111/acel.14326. Epub 2024 Oct 1. Aging Cell. 2024. PMID: 39354697 Free PMC article.

8

Nicotinamide Adenine Dinucleotide in Aging Biology: Potential Applications and Many Unknowns.

Bhasin S, Seals D, Migaud M, Musi N, Baur JA. Bhasin S, et al. Endocr Rev. 2023 Nov 9;44(6):1047-1073. doi: 10.1210/endrev/bnad019. Endocr Rev. 2023. PMID: 37364580 Free PMC article. Review.

9

Nicotinamide riboside and nicotinamide mononucleotide facilitate NAD⁺ synthesis via enterohepatic circulation.

Yaku K, Palikhe S, Iqbal T, Hayat F, Watanabe Y, Fujisaka S, Izumi H, Yoshida T, Karim M, Uchida H, Nawaz A, Tobe K, Mori H, Migaud ME, Nakagawa T. Yaku K, et al. Among authors: migaud me. Sci Adv. 2025 Mar 21;11(12):eadr1538. doi: 10.1126/sciadv.adr1538. Epub 2025 Mar 21. Sci Adv. 2025. PMID: 40117359 Free PMC article.

10

Subcellular NAD⁺ pools are interconnected and buffered by mitochondrial NAD.

Høyland LE, VanLinden MR, Niere M, Strømland Ø, Sharma S, Dietze J, Tolås I, Lucena E, Bifulco E, Sverkeli LJ, Cimadamore-Werthein C, Ashrafi H, Haukanes KF, van der Hoeven B, Dölle C, Davidsen C, Pettersen IKN, Tronstad KJ, Mjøs SA, Hayat F, Makarov MV, Migaud ME, Heiland I, Ziegler M. Høyland LE, et al. Among authors: migaud me. Nat Metab. 2024 Dec;6(12):2319-2337. doi: 10.1038/s42255-024-01174-w. Epub 2024 Dec 13. Nat Metab. 2024. PMID: 39702414

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