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Multi-analyte proteomic analysis identifies blood-based neuroinflammation, cerebrovascular and synaptic biomarkers in preclinical Alzheimer's disease.
Zeng X, Lafferty TK, Sehrawat A, Chen Y, Ferreira PCL, Bellaver B, Povala G, Kamboh MI, Klunk WE, Cohen AD, Lopez OL, Ikonomovic MD, Pascoal TA, Ganguli M, Villemagne VL, Snitz BE, Karikari TK. Zeng X, et al. Among authors: villemagne vl. medRxiv [Preprint]. 2024 Jun 16:2024.06.15.24308975. doi: 10.1101/2024.06.15.24308975. medRxiv. 2024. Update in: Mol Neurodegener. 2024 Oct 10;19(1):68. doi: 10.1186/s13024-024-00753-5. PMID: 38947065 Free PMC article. Updated. Preprint.
Novel CYP1B1-RMDN2 Alzheimer's disease locus identified by genome-wide association analysis of cerebral tau deposition on PET.
Nho K, Risacher SL, Apostolova L, Bice PJ, Brosch J, Deardorff R, Faber K, Farlow MR, Foroud T, Gao S, Rosewood T, Kim JP, Nudelman K, Yu M, Aisen P, Sperling R, Hooli B, Shcherbinin S, Svaldi D, Jack CR, Jagust WJ, Landau S, Vasanthakumar A, Waring JF, Doré V, Laws SM, Masters CL, Porter T, Rowe CC, Villemagne VL, Dumitrescu L, Hohman TJ, Libby JB, Mormino E, Buckley RF, Johnson K, Yang HS, Petersen RC, Ramanan VK, Vemuri P, Cohen AD, Fan KH, Kamboh MI, Lopez OL, Bennett DA, Ali M, Benzinger T, Cruchaga C, Hobbs D, De Jager PL, Fujita M, Jadhav V, Lamb BT, Tsai AP, Castanho I, Mill J, Weiner MW; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Alzheimer’s Disease Neuroimaging Initiative – Department of Defense; Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Study (A4 Study); Australian Imaging, Biomarker & Lifestyle Study (AIBL); Saykin AJ. Nho K, et al. Among authors: villemagne vl. medRxiv [Preprint]. 2023 Mar 22:2023.02.27.23286048. doi: 10.1101/2023.02.27.23286048. medRxiv. 2023. PMID: 36993271 Free PMC article. Preprint.
A novel ultrasensitive assay for plasma p-tau217: performance in individuals with subjective cognitive decline and early Alzheimer's disease.
Gonzalez-Ortiz F, Ferreira PCL, Gonzalez A, Montoliu-Gaya L, Ortiz-Romero P, Kac PR, Turton M, Kvartsberg H, Ashton NJ, Zetterberg H, Harrison P, Bellaver B, Povala G, Villemagne VL, Pascoal TA, Ganguli M, Cohen AD, Miguillon C, Contador J, Suarez-Calvet M, Karikari TK, Blennow K. Gonzalez-Ortiz F, et al. Among authors: villemagne vl. medRxiv [Preprint]. 2023 Oct 5:2023.09.26.23296134. doi: 10.1101/2023.09.26.23296134. medRxiv. 2023. Update in: Alzheimers Dement. 2024 Feb;20(2):1239-1249. doi: 10.1002/alz.13525. PMID: 37873312 Free PMC article. Updated. Preprint.
Effect of blood collection tube containing protease inhibitors on the pre-analytical stability of Alzheimer's disease plasma biomarkers.
Chen Y, Zeng X, Lee J, Sehrawat A, Lafferty TK, Boslett JJ, Klunk WE, Pascoal TA, Villemagne VL, Cohen AD, Lopez O, Yates NA, Karikari TK. Chen Y, et al. Among authors: villemagne vl. medRxiv [Preprint]. 2024 Mar 7:2024.03.05.24303504. doi: 10.1101/2024.03.05.24303504. medRxiv. 2024. Update in: J Neurochem. 2024 Sep;168(9):2736-2750. doi: 10.1111/jnc.16130. PMID: 38496591 Free PMC article. Updated. Preprint.
Apolipoprotein E and Alzheimer's disease pathology in African American older adults.
Royse SK, Snitz BE, Hill AV, Reese AC, Roush RE, Kamboh MI, Bertolet M, Saeed A, Lopresti BJ, Villemagne VL, Lopez OL, Reis SE, Becker JT, Cohen AD. Royse SK, et al. Among authors: villemagne vl. Neurobiol Aging. 2024 Jul;139:11-19. doi: 10.1016/j.neurobiolaging.2024.03.005. Epub 2024 Mar 30. Neurobiol Aging. 2024. PMID: 38582070
Alzheimer blood biomarkers: practical guidelines for study design, sample collection, processing, biobanking, measurement and result reporting.
Zeng X, Chen Y, Sehrawat A, Lee J, Lafferty TK, Kofler J, Berman SB, Sweet RA, Tudorascu DL, Klunk WE, Ikonomovic MD, Pfister A, Zetterberg H, Snitz BE, Cohen AD, Villemagne VL, Pascoal TA, Kamboh MI, Lopez OI, Blennow K, Karikari TK. Zeng X, et al. Among authors: villemagne vl. Mol Neurodegener. 2024 May 15;19(1):40. doi: 10.1186/s13024-024-00711-1. Mol Neurodegener. 2024. PMID: 38750570 Free PMC article. Review.
A streamlined, resource-efficient immunoprecipitation-mass spectrometry method for quantifying plasma amyloid-β biomarkers in Alzheimer's disease.
Karikari T, Chen Y, Zeng X, Olvera-Rojas M, Sehrawat A, Lafferty T, Pascoal T, Villemagne V, Solis-Urra P, Triviño-Ibañez E, Gómez-Rí M, Cohen A, Ikonomovic M, Esteban-Cornejo I, Erickson K, Lopez O, Yates N. Karikari T, et al. Res Sq [Preprint]. 2024 Sep 2:rs.3.rs-4947448. doi: 10.21203/rs.3.rs-4947448/v1. Res Sq. 2024. PMID: 39281858 Free PMC article. Preprint.
Multi-analyte proteomic analysis identifies blood-based neuroinflammation, cerebrovascular and synaptic biomarkers in preclinical Alzheimer's disease.
Zeng X, Lafferty TK, Sehrawat A, Chen Y, Ferreira PCL, Bellaver B, Povala G, Kamboh MI, Klunk WE, Cohen AD, Lopez OL, Ikonomovic MD, Pascoal TA, Ganguli M, Villemagne VL, Snitz BE, Karikari TK. Zeng X, et al. Among authors: villemagne vl. Mol Neurodegener. 2024 Oct 10;19(1):68. doi: 10.1186/s13024-024-00753-5. Mol Neurodegener. 2024. PMID: 39385222 Free PMC article.
Plasma biomarkers identify brain ATN abnormalities in a dementia-free population-based cohort.
Dresse MT, Ferreira PCL, Prasadan A, Diaz JL, Zeng X, Bellaver B, Povala G, Villemagne VL, Kamboh MI, Cohen AD, Pascoal TA, Ganguli M, Snitz BE, Shaaban CE, Karikari TK. Dresse MT, et al. Among authors: villemagne vl. medRxiv [Preprint]. 2025 Apr 28:2025.04.27.25326360. doi: 10.1101/2025.04.27.25326360. medRxiv. 2025. PMID: 40343022 Free PMC article. Preprint.
439 results