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Page 1
Tumor evolution metrics predict recurrence beyond 10 years in locally advanced prostate cancer.
Fernandez-Mateos J, Cresswell GD, Trahearn N, Webb K, Sakr C, Lampis A, Stuttle C, Corbishley CM, Stavrinides V, Zapata L, Spiteri I, Heide T, Gallagher L, James C, Ramazzotti D, Gao A, Kote-Jarai Z, Acar A, Truelove L, Proszek P, Murray J, Reid A, Wilkins A, Hubank M, Eeles R, Dearnaley D, Sottoriva A. Fernandez-Mateos J, et al. Among authors: james c. Nat Cancer. 2024 Sep;5(9):1334-1351. doi: 10.1038/s43018-024-00787-0. Epub 2024 Jul 12. Nat Cancer. 2024. PMID: 38997466 Free PMC article.
The co-evolution of the genome and epigenome in colorectal cancer.
Heide T, Househam J, Cresswell GD, Spiteri I, Lynn C, Mossner M, Kimberley C, Fernandez-Mateos J, Chen B, Zapata L, James C, Barozzi I, Chkhaidze K, Nichol D, Gunasri V, Berner A, Schmidt M, Lakatos E, Baker AM, Costa H, Mitchinson M, Piazza R, Jansen M, Caravagna G, Ramazzotti D, Shibata D, Bridgewater J, Rodriguez-Justo M, Magnani L, Graham TA, Sottoriva A. Heide T, et al. Among authors: james c. Nature. 2022 Nov;611(7937):733-743. doi: 10.1038/s41586-022-05202-1. Epub 2022 Oct 26. Nature. 2022. PMID: 36289335 Free PMC article.
Phenotypic plasticity and genetic control in colorectal cancer evolution.
Househam J, Heide T, Cresswell GD, Spiteri I, Kimberley C, Zapata L, Lynn C, James C, Mossner M, Fernandez-Mateos J, Vinceti A, Baker AM, Gabbutt C, Berner A, Schmidt M, Chen B, Lakatos E, Gunasri V, Nichol D, Costa H, Mitchinson M, Ramazzotti D, Werner B, Iorio F, Jansen M, Caravagna G, Barnes CP, Shibata D, Bridgewater J, Rodriguez-Justo M, Magnani L, Sottoriva A, Graham TA. Househam J, et al. Among authors: james c. Nature. 2022 Nov;611(7937):744-753. doi: 10.1038/s41586-022-05311-x. Epub 2022 Oct 26. Nature. 2022. PMID: 36289336 Free PMC article.
Contribution of pks+ E. coli mutations to colorectal carcinogenesis.
Chen B, Ramazzotti D, Heide T, Spiteri I, Fernandez-Mateos J, James C, Magnani L, Graham TA, Sottoriva A. Chen B, et al. Among authors: james c. Nat Commun. 2023 Nov 29;14(1):7827. doi: 10.1038/s41467-023-43329-5. Nat Commun. 2023. PMID: 38030613 Free PMC article.
Long-term Multimodal Recording Reveals Epigenetic Adaptation Routes in Dormant Breast Cancer Cells.
Rosano D, Sofyali E, Dhiman H, Ghirardi C, Ivanoiu D, Heide T, Vingiani A, Bertolotti A, Pruneri G, Canale E, Dewhurst HF, Saha D, Slaven N, Barozzi I, Li T, Zemlyanskiy G, Phillips H, James C, Győrffy B, Lynn C, Cresswell GD, Rehman F, Noberini R, Bonaldi T, Sottoriva A, Magnani L. Rosano D, et al. Among authors: james c. Cancer Discov. 2024 May 1;14(5):866-889. doi: 10.1158/2159-8290.CD-23-1161. Cancer Discov. 2024. PMID: 38527495 Free PMC article.
Epigenetic Heritability of Cell Plasticity Drives Cancer Drug Resistance through a One-to-Many Genotype-to-Phenotype Paradigm.
Oliveira EA, Milite S, Fernandez-Mateos J, Cresswell GD, Yara-Romero E, Vlachogiannis G, Chen B, James CT, Patruno L, Ascolani G, Acar A, Heide T, Spiteri I, Graudenzi A, Caravagna G, Bertotti A, Graham TA, Magnani L, Valeri N, Sottoriva A. Oliveira EA, et al. Among authors: james ct. Cancer Res. 2025 Jun 11. doi: 10.1158/0008-5472.CAN-25-0999. Online ahead of print. Cancer Res. 2025. PMID: 40499006
Chemotherapy induces canalization of cell state in childhood B-cell precursor acute lymphoblastic leukemia.
Turati VA, Guerra-Assunção JA, Potter NE, Gupta R, Ecker S, Daneviciute A, Tarabichi M, Webster AP, Ding C, May G, James C, Brown J, Conde L, Russell LJ, Ancliff P, Inglott S, Cazzaniga G, Biondi A, Hall GW, Lynch M, Hubank M, Macaulay I, Beck S, Van Loo P, Jacobsen SE, Greaves M, Herrero J, Enver T. Turati VA, et al. Among authors: james c. Nat Cancer. 2021 Aug;2(8):835-852. doi: 10.1038/s43018-021-00219-3. Epub 2021 Jul 5. Nat Cancer. 2021. PMID: 34734190 Free PMC article.
Generation and trapping of a mesoderm biased state of human pluripotency.
Stavish D, Böiers C, Price C, Frith TJR, Halliwell J, Saldaña-Guerrero I, Wray J, Brown J, Carr J, James C, Barbaric I, Andrews PW, Enver T. Stavish D, et al. Among authors: james c. Nat Commun. 2020 Oct 5;11(1):4989. doi: 10.1038/s41467-020-18727-8. Nat Commun. 2020. PMID: 33020476 Free PMC article.
An instructive role for Interleukin-7 receptor α in the development of human B-cell precursor leukemia.
Geron I, Savino AM, Fishman H, Tal N, Brown J, Turati VA, James C, Sarno J, Hameiri-Grossman M, Lee YN, Rein A, Maniriho H, Birger Y, Zemlyansky A, Muler I, Davis KL, Marcu-Malina V, Mattson N, Parnas O, Wagener R, Fischer U, Barata JT, Jamieson CHM, Müschen M, Chen CW, Borkhardt A, Kirsch IR, Nagler A, Enver T, Izraeli S. Geron I, et al. Among authors: james c. Nat Commun. 2022 Feb 3;13(1):659. doi: 10.1038/s41467-022-28218-7. Nat Commun. 2022. PMID: 35115489 Free PMC article.
2,603 results