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Page 1
Computational pathology applied to clinical colorectal cancer cohorts identifies immune and endothelial cell spatial patterns predictive of outcome.
Trahearn N, Sakr C, Banerjee A, Lee SH, Baker AM, Kocher HM, Angerilli V, Morano F, Bergamo F, Maddalena G, Intini R, Cremolini C, Caravagna G, Graham T, Pietrantonio F, Lonardi S, Fassan M, Sottoriva A. Trahearn N, et al. J Pathol. 2025 Feb;265(2):198-210. doi: 10.1002/path.6378. J Pathol. 2025. PMID: 39788558 Free PMC article.
Tumor evolution metrics predict recurrence beyond 10 years in locally advanced prostate cancer.
Fernandez-Mateos J, Cresswell GD, Trahearn N, Webb K, Sakr C, Lampis A, Stuttle C, Corbishley CM, Stavrinides V, Zapata L, Spiteri I, Heide T, Gallagher L, James C, Ramazzotti D, Gao A, Kote-Jarai Z, Acar A, Truelove L, Proszek P, Murray J, Reid A, Wilkins A, Hubank M, Eeles R, Dearnaley D, Sottoriva A. Fernandez-Mateos J, et al. Among authors: trahearn n. Nat Cancer. 2024 Sep;5(9):1334-1351. doi: 10.1038/s43018-024-00787-0. Epub 2024 Jul 12. Nat Cancer. 2024. PMID: 38997466 Free PMC article.
Epigenome and early selection determine the tumour-immune evolutionary trajectory of colorectal cancer.
Lakatos E, Gunasri V, Zapata L, Househam J, Heide T, Trahearn N, Swinyard O, Cisneros L, Lynn C, Mossner M, Kimberley C, Spiteri I, Cresswell GD, Llibre-Palomar G, Mitchison M, Maley CC, Jansen M, Rodriguez-Justo M, Bridgewater J, Baker AM, Sottoriva A, Graham TA. Lakatos E, et al. Among authors: trahearn n. bioRxiv [Preprint]. 2024 Feb 14:2024.02.12.579956. doi: 10.1101/2024.02.12.579956. bioRxiv. 2024. PMID: 38405882 Free PMC article. Preprint.
Magnetic Resonance Imaging Follow-up of Targeted Biopsy-negative Prostate Lesions.
Stavrinides V, Eksi E, Finn R, Texeira-Mendes L, Rana S, Trahearn N, Grey A, Giganti F, Huet E, Fiard G, Freeman A, Haider A, Allen C, Kirkham A, Cole AP, Collins T, Pendse D, Dickinson L, Punwani S, Pashayan N, Emberton M, Moore CM, Orczyk C. Stavrinides V, et al. Among authors: trahearn n. Eur Urol Focus. 2023 Sep;9(5):781-787. doi: 10.1016/j.euf.2023.03.011. Epub 2023 Apr 6. Eur Urol Focus. 2023. PMID: 37031096 Free article.
Regional Histopathology and Prostate MRI Positivity: A Secondary Analysis of the PROMIS Trial.
Stavrinides V, Norris JM, Karapanagiotis S, Giganti F, Grey A, Trahearn N, Freeman A, Haider A, Carmona Echeverría LM, Bott SRJ, Brown LC, Burns-Cox N, Dudderidge TJ, El-Shater Bosaily A, Ghei M, Henderson A, Hindley RG, Kaplan RS, Oldroyd R, Parker C, Persad R, Rosario DJ, Shergill IS, Winkler M, Kirkham A, Punwani S, Whitaker HC, Ahmed HU, Emberton M; PROMIS Group. Stavrinides V, et al. Among authors: trahearn n. Radiology. 2023 Apr;307(1):e220762. doi: 10.1148/radiol.220762. Epub 2022 Dec 13. Radiology. 2023. PMID: 36511804 Free PMC article.
Exploiting evolutionary steering to induce collateral drug sensitivity in cancer.
Acar A, Nichol D, Fernandez-Mateos J, Cresswell GD, Barozzi I, Hong SP, Trahearn N, Spiteri I, Stubbs M, Burke R, Stewart A, Caravagna G, Werner B, Vlachogiannis G, Maley CC, Magnani L, Valeri N, Banerji U, Sottoriva A. Acar A, et al. Among authors: trahearn n. Nat Commun. 2020 Apr 21;11(1):1923. doi: 10.1038/s41467-020-15596-z. Nat Commun. 2020. PMID: 32317663 Free PMC article.
The Spatiotemporal Evolution of Lymph Node Spread in Early Breast Cancer.
Barry P, Vatsiou A, Spiteri I, Nichol D, Cresswell GD, Acar A, Trahearn N, Hrebien S, Garcia-Murillas I, Chkhaidze K, Ermini L, Huntingford IS, Cottom H, Zabaglo L, Koelble K, Khalique S, Rusby JE, Muscara F, Dowsett M, Maley CC, Natrajan R, Yuan Y, Schiavon G, Turner N, Sottoriva A. Barry P, et al. Among authors: trahearn n. Clin Cancer Res. 2018 Oct 1;24(19):4763-4770. doi: 10.1158/1078-0432.CCR-17-3374. Epub 2018 Jun 11. Clin Cancer Res. 2018. PMID: 29891724 Free PMC article.
12 results