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Page 1
The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases uncovers cholesterol as a regulator of astrocyte reactivity impaired by ApoE4.
Feringa FM, Hertog SJK, Wang L, Derks RJE, Kruijff I, Erlebach L, Heijneman J, Miramontes R, Pömpner N, Blomberg N, Olivier-Jimenez D, Johansen LE, Cammack AJ, Giblin A, Toomey CE, Rose IVL, Yuan H, Ward M, Isaacs AM, Kampmann M, Kronenberg-Versteeg D, Lashley T, Thompson LM, Ori A, Mohammed Y, Giera M, van der Kant R. Feringa FM, et al. Among authors: isaacs am. bioRxiv [Preprint]. 2024 Jul 3:2024.07.01.601474. doi: 10.1101/2024.07.01.601474. bioRxiv. 2024. PMID: 39005258 Free PMC article. Preprint.
A multimodal screening platform for endogenous dipeptide repeat proteins in C9orf72 patient iPSC neurons.
Hölbling BV, Gupta Y, Marchi PM, Atilano ML, Flower M, Ureña E, Goulden RA, Dobbs HK, Katona E, Mikheenko A, Giblin A, Awan AR, Fisher-Ward CL, O'Brien N, Vaizoglu D, Kempthorne L, Wilson KM, Gittings LM, Carcolé M, Ruepp MD, Mizielinska S, Partridge L, Fratta P, Tabrizi SJ, Selvaraj BT, Chandran S, Armstrong E, Whiting P, Isaacs AM. Hölbling BV, et al. Among authors: isaacs am. Cell Rep. 2025 May 27;44(5):115695. doi: 10.1016/j.celrep.2025.115695. Epub 2025 May 10. Cell Rep. 2025. PMID: 40349338 Free article.
Complex shunt system comparison: an observational study by the Hydrocephalus Clinical Research Network.
Jackson EM, Jensen H, Reeder RW, Chiarelli PA, Chu J, Hankinson TC, Hauptman JS, Isaacs AM, Kulkarni AV, Limbrick DD, McDonald PJ, Pindrik JA, Pollack IF, Rocque BG, Rozzelle CJ, Strahle JM, Tamber MS, Wellons JC, Kestle JRW, Whitehead WE, Riva-Cambrin J. Jackson EM, et al. Among authors: isaacs am. J Neurosurg Pediatr. 2025 May 2:1-8. doi: 10.3171/2025.2.PEDS24622. Online ahead of print. J Neurosurg Pediatr. 2025. PMID: 40315602
Differential neuronal vulnerability to C9orf72 repeat expansion driven by Xbp1-induced endoplasmic reticulum-associated degradation.
Shen D, Vincent A, Udine E, Buhidma Y, Anoar S, Tsintzas E, Maeland M, Xu D, Carcolé M, Osumi-Sutherland D, Aleyakpo B, Hull A, Martínez Corrales G, Woodling N, Rademakers R, Isaacs AM, Frigerio C, van Blitterswijk M, Lashley T, Niccoli T. Shen D, et al. Among authors: isaacs am. Cell Rep. 2025 Apr 22;44(4):115459. doi: 10.1016/j.celrep.2025.115459. Epub 2025 Apr 8. Cell Rep. 2025. PMID: 40203833 Free article.
Racial disparities in hydrocephalus mortality and shunt revision: a study from the Hydrocephalus Clinical Research Network.
Rocque BG, Jensen H, Reeder RW, Rozzelle CJ, Kulkarni AV, Pollack IF, McDowell MM, Naftel RP, Jackson EM, Whitehead WE, Pindrik JA, Isaacs AM, Strahle JM, McDonald PJ, Tamber MS, Hankinson TC, Browd SR, Hauptman JS, Krieger MD, Chu J, Riva-Cambrin J, Limbrick DD, Holubkov R, Kestle JRW, Wellons JC. Rocque BG, et al. Among authors: isaacs am. J Neurosurg Pediatr. 2025 Mar 21;35(6):554-562. doi: 10.3171/2024.12.PEDS24371. Print 2025 Jun 1. J Neurosurg Pediatr. 2025. PMID: 40117669
Author Correction: Neuronal polyunsaturated fatty acids are protective in ALS/FTD.
Giblin A, Cammack AJ, Blomberg N, Anoar S, Mikheenko A, Carcolé M, Atilano ML, Hull A, Shen D, Wei X, Coneys R, Zhou L, Mohammed Y, Olivier-Jimenez D, Wang LY, Kinghorn KJ, Niccoli T, Coyne AN, van der Kant R, Lashley T, Giera M, Partridge L, Isaacs AM. Giblin A, et al. Among authors: isaacs am. Nat Neurosci. 2025 Apr;28(4):913. doi: 10.1038/s41593-025-01926-1. Nat Neurosci. 2025. PMID: 40055545 Free PMC article. No abstract available.
158 results