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Autoimmune hypothyroidism GWAS reveals independent autoimmune and thyroid-specific contributions and an inverse relation with cancer risk.
Reeve M, Kanai M, Graham D, Karjalainen J, Luo S, Kolosov N, Adams C, Ritari J, Karczewski K, Kiiskinen T, Fuller Z, Mehtonen J, Kurki M, Khan Z, Partanen J, McCarthy M, Artomov M, Tuomi T, Pirinen M, Kero J, Xavier R, Daly M, Ripatti S, Gen F. Reeve M, et al. Among authors: xavier r. Res Sq [Preprint]. 2024 Jul 8:rs.3.rs-4626646. doi: 10.21203/rs.3.rs-4626646/v1. Res Sq. 2024. PMID: 39041034 Free PMC article. Preprint.
Unusual Phospholipids from Morganella morganii Linked to Depression.
Bang S, Shin YH, Park SM, Deng L, Williamson RT, Graham DB, Xavier RJ, Clardy J. Bang S, et al. Among authors: xavier rj. J Am Chem Soc. 2025 Jan 29;147(4):2998-3002. doi: 10.1021/jacs.4c15158. Epub 2025 Jan 16. J Am Chem Soc. 2025. PMID: 39818770 Free PMC article.
Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population.
Rivas MA, Avila BE, Koskela J, Huang H, Stevens C, Pirinen M, Haritunians T, Neale BM, Kurki M, Ganna A, Graham D, Glaser B, Peter I, Atzmon G, Barzilai N, Levine AP, Schiff E, Pontikos N, Weisburd B, Lek M, Karczewski KJ, Bloom J, Minikel EV, Petersen BS, Beaugerie L, Seksik P, Cosnes J, Schreiber S, Bokemeyer B, Bethge J; International IBD Genetics Consortium; NIDDK IBD Genetics Consortium; T2D-GENES Consortium; Heap G, Ahmad T, Plagnol V, Segal AW, Targan S, Turner D, Saavalainen P, Farkkila M, Kontula K, Palotie A, Brant SR, Duerr RH, Silverberg MS, Rioux JD, Weersma RK, Franke A, Jostins L, Anderson CA, Barrett JC, MacArthur DG, Jalas C, Sokol H, Xavier RJ, Pulver A, Cho JH, McGovern DPB, Daly MJ. Rivas MA, et al. Among authors: xavier rj. PLoS Genet. 2018 May 24;14(5):e1007329. doi: 10.1371/journal.pgen.1007329. eCollection 2018 May. PLoS Genet. 2018. PMID: 29795570 Free PMC article.
Single-cell and spatial transcriptomics of stricturing Crohn's disease highlights a fibrosis-associated network.
Kong L, Subramanian S, Segerstolpe Å, Tran V, Shih AR, Carter GT, Kunitake H, Twardus SW, Li J, Gandhi S, Kaper ME, Cauley C, Chen EJ, Porter CBM, Delorey TM, Bordeianou L, Ricciardi R, Ananthakrishnan AN, Lau H, Graham DB, Hodin R, Deguine J, Smillie CS, Xavier RJ. Kong L, et al. Among authors: xavier rj. Nat Genet. 2025 Jun 25. doi: 10.1038/s41588-025-02225-y. Online ahead of print. Nat Genet. 2025. PMID: 40562913
Serum proteomic and metabolomic analyses from patients with IBD identify biological pathways associated with treatment success with anti-integrin therapy.
Rioux JD, Boucher G, Forest A, Bouchard B, Coderre L, Daneault C, Frayne IR, Legault JT, Bitton A, Ananthakrishnan A, Lesage S, Xavier RJ, Des Rosiers C; iGenoMed Consortium. Rioux JD, et al. Among authors: xavier rj. Immunol Cell Biol. 2025 Jun 12. doi: 10.1111/imcb.70039. Online ahead of print. Immunol Cell Biol. 2025. PMID: 40509637
1,179 results