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Page 1
Guselkumab binding to CD64+ IL-23-producing myeloid cells enhances potency for neutralizing IL-23 signaling.
Sachen KL, Hammaker D, Sarabia I, Stoveken B, Hartman J, Leppard KL, Manieri NA, Bao P, Greving C, Lacy ER, DuPrie M, Wertheimer J, Deming JD, Brown J, Hart A, Li HH, Freeman TC, Keyes B, Kohler K, White I, Karpowich N, Steele R, Elloso MM, Fakharzadeh S, Goyal K, Lavie F, Abreu MT, Allez M, Atreya R, Bissonnette R, Eyerich K, Krueger JG, McGonagle D, McInnes IB, Ritchlin C, Fourie AM. Sachen KL, et al. Among authors: greving c. Front Immunol. 2025 Mar 12;16:1532852. doi: 10.3389/fimmu.2025.1532852. eCollection 2025. Front Immunol. 2025. PMID: 40145093 Free PMC article.
IL-23 tunes inflammatory functions of human mucosal-associated invariant T cells.
Camard L, Stephen T, Yahia-Cherbal H, Guillemot V, Mella S, Baillet V, Lopez-Maestre H, Capocefalo D, Cantini L, Leloup C, Marsande J, Garro K, Sienes Bailo J, Dangien A, Pietrosemoli N, Hasan M, Wang H, Eckle SBG, Fourie AM, Greving C, Joyce-Shaikh B, Parker R, Cua DJ, Bianchi E, Rogge L. Camard L, et al. Among authors: greving c. iScience. 2025 Jan 25;28(2):111898. doi: 10.1016/j.isci.2025.111898. eCollection 2025 Feb 21. iScience. 2025. PMID: 40008359 Free PMC article.
JNJ-77242113, a highly potent, selective peptide targeting the IL-23 receptor, provides robust IL-23 pathway inhibition upon oral dosing in rats and humans.
Fourie AM, Cheng X, Chang L, Greving C, Li X, Knight B, Polidori D, Patrick A, Bains T, Steele R, Allen SJ, Patch RJ, Sun C, Somani S, Bhandari A, Liu D, Huie K, Li S, Rodriguez MA, Xue X, Kannan A, Kosoglou T, Sherlock JP, Towne J, Holland MC, Modi NB. Fourie AM, et al. Among authors: greving c. Sci Rep. 2024 Jul 30;14(1):17515. doi: 10.1038/s41598-024-67371-5. Sci Rep. 2024. PMID: 39080319 Free PMC article.
A Role for IL-12 in IBD after All?
Greving CNA, Towne JE. Greving CNA, et al. Immunity. 2019 Aug 20;51(2):209-211. doi: 10.1016/j.immuni.2019.07.008. Immunity. 2019. PMID: 31433967 Free article.