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Page 1
Extended survival of 9- and 10-gene-edited pig heart xenografts with ischemia minimization and CD154 costimulation blockade-based immunosuppression.
Chaban R, Ileka I, McGrath G, Kinoshita K, Habibabady Z, Ma M, Diaz V, Maenaka A, Calhoun A, Dufault M, Rosales I, Laguerre CM, Sanatkar SA, Burdorf L, Ayares DL, Eyestone W, Sardana P, Kuravi K, Sorrells L, Lederman S, Lucas CG, Prather RS, Wells KD, Whitworth KM, Cooper DKC, Pierson RN 3rd. Chaban R, et al. Among authors: eyestone w. J Heart Lung Transplant. 2024 Dec;43(12):1932-1944. doi: 10.1016/j.healun.2024.07.022. Epub 2024 Aug 7. J Heart Lung Transplant. 2024. PMID: 39097214
Physiological basis for xenotransplantation from genetically modified pigs to humans.
Peterson L, Yacoub MH, Ayares D, Yamada K, Eisenson D, Griffith BP, Mohiuddin MM, Eyestone W, Venter JC, Smolenski RT, Rothblatt M. Peterson L, et al. Among authors: eyestone w. Physiol Rev. 2024 Jul 1;104(3):1409-1459. doi: 10.1152/physrev.00041.2023. Epub 2024 Mar 22. Physiol Rev. 2024. PMID: 38517040 Free PMC article. Review.
Progressive genetic modifications of porcine cardiac xenografts extend survival to 9 months.
Mohiuddin MM, Goerlich CE, Singh AK, Zhang T, Tatarov I, Lewis B, Sentz F, Hershfeld A, Braileanu G, Odonkor P, Strauss E, Williams B, Burke A, Hittman J, Bhutta A, Tabatabai A, Gupta A, Vaught T, Sorrells L, Kuravi K, Dandro A, Eyestone W, Kaczorowski DJ, Ayares D, Griffith BP. Mohiuddin MM, et al. Among authors: eyestone w. Xenotransplantation. 2022 May;29(3):e12744. doi: 10.1111/xen.12744. Epub 2022 Mar 31. Xenotransplantation. 2022. PMID: 35357044 Free PMC article.
Effects of human TFPI and CD47 expression and selectin and integrin inhibition during GalTKO.hCD46 pig lung perfusion with human blood.
Miura S, Habibabady ZA, Pollok F, Connolly M, Pratts S, Dandro A, Sorrells L, Karavi K, Phelps C, Eyestone W, Ayares D, Burdorf L, Azimzadeh A, Pierson RN 3rd. Miura S, et al. Among authors: eyestone w. Xenotransplantation. 2022 Mar;29(2):e12725. doi: 10.1111/xen.12725. Epub 2022 Mar 2. Xenotransplantation. 2022. PMID: 35234315 Free PMC article.
hEPCR.hTBM.hCD47.hHO-1 with donor clodronate and DDAVP treatment improves perfusion and function of GalTKO.hCD46 porcine livers perfused with human blood.
Cimeno A, Kuravi K, Sorrells L, Dandro A, Sendil S, Burdorf L, Parsell DM, Eyestone W, Phelps C, Ayares D, Azimzadeh AM, Pierson RN 3rd, Barth RN, LaMattina JC. Cimeno A, et al. Among authors: eyestone w. Xenotransplantation. 2022 Mar;29(2):e12731. doi: 10.1111/xen.12731. Epub 2022 Feb 15. Xenotransplantation. 2022. PMID: 35166407 Free PMC article.
Humanized von Willebrand factor reduces platelet sequestration in ex vivo and in vivo xenotransplant models.
Connolly MR, Kuravi K, Burdorf L, Sorrells L, Morrill B, Cimeno A, Vaught T, Dandro A, Sendil S, Habibabady ZA, Monahan J, Li T, LaMattina J, Eyestone W, Ayares D, Phelps C, Azimzadeh AM, Pierson RN 3rd. Connolly MR, et al. Among authors: eyestone w. Xenotransplantation. 2021 Nov;28(6):e12712. doi: 10.1111/xen.12712. Epub 2021 Oct 17. Xenotransplantation. 2021. PMID: 34657336 Free PMC article.
47 results