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Predicting Alzheimer's disease subtypes and understanding their molecular characteristics in living patients with transcriptomic trajectory profiling.
Huang X, Jannu AJ, Song Z, Jury-Garfe N, Lasagna-Reeves CA; Alzheimer's Disease Neuroimaging Initiative; Johnson TS, Huang K, Zhang J. Huang X, et al. Among authors: jury garfe n. Alzheimers Dement. 2025 Jan;21(1):e14241. doi: 10.1002/alz.14241. Epub 2025 Jan 15. Alzheimers Dement. 2025. PMID: 39812331 Free PMC article.
Phosphorylation at serine 214 correlates with tau seeding activity in an age-dependent manner in two mouse models for tauopathies and is required for tau transsynaptic propagation.
Martinez P, Jury-Garfe N, Patel H, You Y, Perkins A, You Y, Lee-Gosselin A, Vidal R, Lasagna-Reeves CA. Martinez P, et al. Among authors: jury garfe n. bioRxiv [Preprint]. 2024 Jul 23:2024.07.22.604618. doi: 10.1101/2024.07.22.604618. bioRxiv. 2024. PMID: 39211286 Free PMC article. Preprint.
Therapeutic targeting of immunometabolism reveals a critical reliance on hexokinase 2 dosage for microglial activation and Alzheimer's progression.
Codocedo JF, Mera-Reina C, Bor-Chian Lin P, Fallen PB, Puntambekar SS, Casali BT, Jury-Garfe N, Martinez P, Lasagna-Reeves CA, Landreth GE. Codocedo JF, et al. Among authors: jury garfe n. Cell Rep. 2024 Jul 23;43(7):114488. doi: 10.1016/j.celrep.2024.114488. Epub 2024 Jul 13. Cell Rep. 2024. PMID: 39002124 Free PMC article.
Enhanced microglial dynamics and paucity of tau seeding in the amyloid plaque microenvironment contributes to cognitive resilience in Alzheimer's disease.
Jury-Garfe N, You Y, Martínez P, Redding-Ochoa J, Karahan H, Johnson TS, Zhang J, Kim J, Troncoso JC, Lasagna-Reeves CA. Jury-Garfe N, et al. bioRxiv [Preprint]. 2023 Jul 28:2023.07.27.550884. doi: 10.1101/2023.07.27.550884. bioRxiv. 2023. Update in: Acta Neuropathol. 2024 Aug 5;148(1):15. doi: 10.1007/s00401-024-02775-1. PMID: 37546928 Free PMC article. Updated. Preprint.
TREM2-Deficient Microglia Attenuate Tau Spreading In Vivo.
Lee-Gosselin A, Jury-Garfe N, You Y, Dabin L, Soni D, Dutta S, Rochet JC, Kim J, Oblak AL, Lasagna-Reeves CA. Lee-Gosselin A, et al. Among authors: jury garfe n. Cells. 2023 Jun 10;12(12):1597. doi: 10.3390/cells12121597. Cells. 2023. PMID: 37371067 Free PMC article.