Lux MC - Search Results

1

Structural basis for transthiolation intermediates in the ubiquitin pathway.

Kochańczyk T, Hann ZS, Lux MC, Delos Reyes AMV, Ji C, Tan DS, Lima CD. Kochańczyk T, et al. Among authors: lux mc. Nature. 2024 Sep;633(8028):216-223. doi: 10.1038/s41586-024-07828-9. Epub 2024 Aug 14. Nature. 2024. PMID: 39143218 Free PMC article.

2

Design and Semisynthesis of Biselectrophile-Functionalized Ubiquitin Probes To Investigate Transthioesterification Reactions.

Delos Reyes AMV, Lux MC, Hann ZS, Ji C, Kochańczyk T, DiBello M, Lima CD, Tan DS. Delos Reyes AMV, et al. Among authors: lux mc. Org Lett. 2024 Jun 7;26(22):4594-4599. doi: 10.1021/acs.orglett.4c01102. Epub 2024 May 23. Org Lett. 2024. PMID: 38781175 Free PMC article.

3

Interrogation of Enantioselectivity in the Photomediated Ring Contractions of Saturated Heterocycles.

Kim SF, Liles JP, Lux MC, Park H, Jurczyk J, Soda Y, Yeung CS, Sigman MS, Sarpong R. Kim SF, et al. Among authors: lux mc. J Am Chem Soc. 2025 Jan 15;147(2):1851-1866. doi: 10.1021/jacs.4c13999. Epub 2025 Jan 2. J Am Chem Soc. 2025. PMID: 39746148 Free PMC article.

4

Mechanistic Investigation, Wavelength-Dependent Reactivity, and Expanded Reactivity of N-Aryl Azacycle Photomediated Ring Contractions.

Kim SF, Schwarz H, Jurczyk J, Nebgen BR, Hendricks H, Park H, Radosevich A, Zuerch MW, Harper K, Lux MC, Yeung CS, Sarpong R. Kim SF, et al. Among authors: lux mc. J Am Chem Soc. 2024 Feb 28;146(8):5580-5596. doi: 10.1021/jacs.3c13982. Epub 2024 Feb 12. J Am Chem Soc. 2024. PMID: 38347659 Free PMC article.

5

Photomediated ring contraction of saturated heterocycles.

Jurczyk J, Lux MC, Adpressa D, Kim SF, Lam YH, Yeung CS, Sarpong R. Jurczyk J, et al. Among authors: lux mc. Science. 2021 Aug 27;373(6558):1004-1012. doi: 10.1126/science.abi7183. Epub 2021 Aug 12. Science. 2021. PMID: 34385352 Free PMC article.

6

Synthesis of Bridged Bicyclic Amines by Intramolecular Amination of Remote C-H Bonds: Synergistic Activation by Light and Heat.

Lux MC, Jurczyk J, Lam YH, Song ZJ, Ma C, Roque JB, Ham JS, Sciammetta N, Adpressa D, Sarpong R, Yeung CS. Lux MC, et al. Org Lett. 2020 Aug 21;22(16):6578-6583. doi: 10.1021/acs.orglett.0c02345. Epub 2020 Aug 10. Org Lett. 2020. PMID: 32806157

7

Structural basis for adenylation and thioester bond formation in the ubiquitin E1.

Hann ZS, Ji C, Olsen SK, Lu X, Lux MC, Tan DS, Lima CD. Hann ZS, et al. Among authors: lux mc. Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15475-15484. doi: 10.1073/pnas.1905488116. Epub 2019 Jun 24. Proc Natl Acad Sci U S A. 2019. PMID: 31235585 Free PMC article.

8

Synthesis of bicyclic ethers by a palladium-catalyzed oxidative cyclization-redox relay-π-allyl-Pd cyclization cascade reaction.

Lux MC, Boby ML, Brooks JL, Tan DS. Lux MC, et al. Chem Commun (Camb). 2019 Jun 21;55(49):7013-7016. doi: 10.1039/c9cc03775f. Epub 2019 May 31. Chem Commun (Camb). 2019. PMID: 31147660 Free PMC article.

9

Targeting adenylate-forming enzymes with designed sulfonyladenosine inhibitors.

Lux MC, Standke LC, Tan DS. Lux MC, et al. J Antibiot (Tokyo). 2019 Jun;72(6):325-349. doi: 10.1038/s41429-019-0171-2. Epub 2019 Apr 15. J Antibiot (Tokyo). 2019. PMID: 30982830 Free PMC article. Review.

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