Fu XJ - Search Results

1

Discovery of novel pyrazolo[1,5-a]pyrimidine derivatives as potent reversal agents against ABCB1-mediated multidrug resistance.

Fu XJ, Li N, Wu J, Wang ZY, Liu RR, Niu JB, Taleb M, Yuan S, Liu HM, Song J, Zhang SY. Fu XJ, et al. Eur J Med Chem. 2024 Nov 5;277:116761. doi: 10.1016/j.ejmech.2024.116761. Epub 2024 Aug 13. Eur J Med Chem. 2024. PMID: 39151276

2

Development of Membrane-Active Honokiol/Magnolol Amphiphiles as Potent Antibacterial Agents against Methicillin-Resistant Staphylococcus aureus (MRSA).

Guo Y, Hou E, Wen T, Yan X, Han M, Bai LP, Fu X, Liu J, Qin S. Guo Y, et al. J Med Chem. 2021 Sep 9;64(17):12903-12916. doi: 10.1021/acs.jmedchem.1c01073. Epub 2021 Aug 25. J Med Chem. 2021. PMID: 34432450

3

Discovery of 1,2,4-triazine dithiocarbamate derivatives as NEDDylation agonists to inhibit gastric cancers.

Song J, Liu Y, Yuan XY, Liu WB, Li YR, Yu GX, Tian XY, Zhang YB, Fu XJ, Zhang SY. Song J, et al. Among authors: fu xj. Eur J Med Chem. 2021 Dec 5;225:113801. doi: 10.1016/j.ejmech.2021.113801. Epub 2021 Aug 26. Eur J Med Chem. 2021. PMID: 34455358

4

A novel aromatic amide derivative SY-65 co-targeted tubulin and histone deacetylase 1 with potent anticancer activity in vitro and in vivo.

Li YR, Liu FF, Liu WB, Zhang YF, Tian XY, Fu XJ, Xu Y, Song J, Zhang SY. Li YR, et al. Among authors: fu xj. Biochem Pharmacol. 2022 Jul;201:115070. doi: 10.1016/j.bcp.2022.115070. Epub 2022 May 5. Biochem Pharmacol. 2022. PMID: 35526597

5

Discovery of novel coumarin-indole derivatives as tubulin polymerization inhibitors with potent anti-gastric cancer activities.

Song J, Guan YF, Liu WB, Song CH, Tian XY, Zhu T, Fu XJ, Qi YQ, Zhang SY. Song J, et al. Among authors: fu xj. Eur J Med Chem. 2022 Aug 5;238:114467. doi: 10.1016/j.ejmech.2022.114467. Epub 2022 May 18. Eur J Med Chem. 2022. PMID: 35605363

6

Discovery of N-benzylarylamide derivatives as novel tubulin polymerization inhibitors capable of activating the Hippo pathway.

Song J, Wang SH, Song CH, Zhang WX, Zhu JX, Tian XY, Fu XJ, Xu Y, Jin CY, Zhang SY. Song J, et al. Among authors: fu xj. Eur J Med Chem. 2022 Oct 5;240:114583. doi: 10.1016/j.ejmech.2022.114583. Epub 2022 Jul 7. Eur J Med Chem. 2022. PMID: 35834904

7

Discovery of novel N-benzylarylamide-dithiocarbamate based derivatives as dual inhibitors of tubulin polymerization and LSD1 that inhibit gastric cancers.

Yuan XY, Song CH, Liu XJ, Wang X, Jia MQ, Wang W, Liu WB, Fu XJ, Jin CY, Song J, Zhang SY. Yuan XY, et al. Among authors: fu xj. Eur J Med Chem. 2023 Apr 5;252:115281. doi: 10.1016/j.ejmech.2023.115281. Epub 2023 Mar 16. Eur J Med Chem. 2023. PMID: 36940611

8

Discovery of a novel Coumarin-Dihydroquinoxalone derivative MY-673 as a tubulin polymerization inhibitor capable of inhibiting the ERK pathway with potent anti-gastric cancer activities.

Song J, Wang SY, Wang X, Jia MQ, Tian XY, Fu XJ, Jin CY, Zhang SY. Song J, et al. Among authors: fu xj. Bioorg Chem. 2023 Aug;137:106580. doi: 10.1016/j.bioorg.2023.106580. Epub 2023 May 2. Bioorg Chem. 2023. PMID: 37149948

9

Discovery of novel arylamide derivatives containing piperazine moiety as inhibitors of tubulin polymerisation with potent liver cancer inhibitory activity.

Shi XY, Jiao H, Zhang JK, Tian XY, Guo DF, Gao J, Jia MQ, Song J, Zhang SY, Fu XJ, Tang HW. Shi XY, et al. Among authors: fu xj. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2237701. doi: 10.1080/14756366.2023.2237701. J Enzyme Inhib Med Chem. 2023. PMID: 37489043 Free PMC article.

10

Semisynthesis and biological evaluation of novel honokiol thioethers against colon cancer cells HCT116 via inhibiting the transcription and expression of YAP protein.

Yang R, Fu X, Fan J, Wang T, Song J, Xu T, Guo Y, Zhang SY. Yang R, et al. Bioorg Med Chem. 2024 Jun 1;107:117762. doi: 10.1016/j.bmc.2024.117762. Epub 2024 May 15. Bioorg Med Chem. 2024. PMID: 38759254

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