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A cell state-specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma.
Banu MA, Dovas A, Argenziano MG, Zhao W, Sperring CP, Cuervo Grajal H, Liu Z, Higgins DM, Amini M, Pereira B, Ye LF, Mahajan A, Humala N, Furnari JL, Upadhyayula PS, Zandkarimi F, Nguyen TT, Teasley D, Wu PB, Hai L, Karan C, Dowdy T, Razavilar A, Siegelin MD, Kitajewski J, Larion M, Bruce JN, Stockwell BR, Sims PA, Canoll P. Banu MA, et al. Among authors: kitajewski j. EMBO J. 2024 Oct;43(20):4492-4521. doi: 10.1038/s44318-024-00176-4. Epub 2024 Aug 27. EMBO J. 2024. PMID: 39192032 Free PMC article.
Notch transcriptional target tmtc1 maintains vascular homeostasis.
Paik NY, Neethling J, Anwar M, Gupta P, Sanborn MA, Shen Z, Bandara T, Hyun J, Naiche LA, Kitajewski JK, Rehman J, Shin JW, Mehta D, Pajcini KV. Paik NY, et al. Among authors: kitajewski jk. Cell Mol Life Sci. 2024 Aug 27;81(1):370. doi: 10.1007/s00018-024-05407-9. Cell Mol Life Sci. 2024. PMID: 39190102 Free PMC article.
Chloride intracellular channel (CLIC) protein function in S1P-induced Rac1 activation requires membrane localization of the C-terminus, but not thiol-transferase nor ion channel activities.
Mao Y, Jesse JJ, Shaye DD, Kitajewski J. Mao Y, et al. Among authors: kitajewski j. bioRxiv [Preprint]. 2025 Jan 24:2025.01.22.634370. doi: 10.1101/2025.01.22.634370. bioRxiv. 2025. Update in: Front Cell Dev Biol. 2025 Apr 01;13:1565262. doi: 10.3389/fcell.2025.1565262. PMID: 39896666 Free PMC article. Updated. Preprint.
Inhibition of Notch4 Using Novel Neutralizing Antibodies Reduces Tumor Growth in Murine Cancer Models by Targeting the Tumor Endothelium.
Eng JW, Kato Y, Adachi Y, Swaminathan B, Naiche LA, Vadakath R, Sakamoto Y, Nakazawa Y, Tachino S, Ito K, Abe T, Minoshima Y, Hoshino-Negishi K, Ogasawara H, Kawakatsu T, Nishimura M, Katayama M, Shimizu M, Tahara K, Sato T, Suzuki K, Agarwala K, Iwata M, Nomoto K, Ozawa Y, Imai T, Funahashi Y, Matsui J, Kitajewski J. Eng JW, et al. Among authors: kitajewski j. Cancer Res Commun. 2024 Jul 1;4(7):1881-1893. doi: 10.1158/2767-9764.CRC-24-0081. Cancer Res Commun. 2024. PMID: 38984877 Free PMC article.
183 results