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ARHGAP12 and ARHGAP29 exert distinct regulatory effects on switching between two cell morphological states through GSK-3 activity.
Cheng VWT, Vaughn-Beaucaire P, Shaw GC, Kriegs M, Droop A, Psakis G, Mittelbronn M, Humphries M, Esteves F, Hayes J, Cockle JV, Knipp S, Rohwedder A, Ismail A, Rominiyi O, Collis SJ, Mavria G, Samarasekara J, Ladbury JE, Ketchen S, Morton R, Fagan S, Tams D, Myers K, McGarrity-Cottrell C, Dunning M, Boissinot M, Michalopoulos G, Prior S, Lam YW, Morrison EE, Short SC, Lawler SE, Brüning-Richardson A. Cheng VWT, et al. Among authors: vaughn beaucaire p. Cell Rep. 2025 Mar 25;44(3):115361. doi: 10.1016/j.celrep.2025.115361. Epub 2025 Mar 6. Cell Rep. 2025. PMID: 40053455 Free article.
Modulation of blood-tumor barrier transcriptional programs improves intratumoral drug delivery and potentiates chemotherapy in GBM.
Jimenez-Macias JL, Vaughn-Beaucaire P, Bharati A, Xu Z, Forrest M, Hong J, Sun M, Schmidt A, Clark J, Hawkins W, Mercado N, Real J, Huntington K, Zdioruk M, Nowicki MO, Cho CF, Wu B, Li W, Logan T, Manz KE, Pennell KD, Fedeles BI, Bertone P, Punsoni M, Brodsky AS, Lawler SE. Jimenez-Macias JL, et al. Among authors: vaughn beaucaire p. Sci Adv. 2025 Feb 28;11(9):eadr1481. doi: 10.1126/sciadv.adr1481. Epub 2025 Feb 26. Sci Adv. 2025. PMID: 40009687 Free PMC article.
Modulation of blood-tumor barrier transcriptional programs improves intra-tumoral drug delivery and potentiates chemotherapy in GBM.
Jimenez-Macias JL, Vaughn-Beaucaire P, Bharati A, Xu Z, Forrest M, Hong J, Sun M, Schmidt A, Clark J, Hawkins W, Mercado N, Real J, Huntington K, Zdioruk M, Nowicki MO, Cho CF, Wu B, Li W, Logan T, Manz KE, Pennell KD, Fedeles BI, Brodsky AS, Lawler SE. Jimenez-Macias JL, et al. Among authors: vaughn beaucaire p. bioRxiv [Preprint]. 2024 Aug 28:2024.08.26.609797. doi: 10.1101/2024.08.26.609797. bioRxiv. 2024. Update in: Sci Adv. 2025 Feb 28;11(9):eadr1481. doi: 10.1126/sciadv.adr1481. PMID: 39253453 Free PMC article. Updated. Preprint.