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Page 1
Enhancer activation from transposable elements in extrachromosomal DNA.
Kraft K, Murphy SE, Jones MG, Shi Q, Bhargava-Shah A, Luong C, Hung KL, He BJ, Li R, Park SK, Weiser NE, Luebeck J, Bafna V, Boeke JD, Mischel PS, Boettiger AN, Chang HY. Kraft K, et al. Among authors: mischel ps. bioRxiv [Preprint]. 2024 Sep 8:2024.09.04.611262. doi: 10.1101/2024.09.04.611262. bioRxiv. 2024. PMID: 39282372 Free PMC article. Preprint.
Coordinated inheritance of extrachromosomal DNA species in human cancer cells.
Hung KL, Jones MG, Wong IT, Lange JT, Luebeck J, Scanu E, He BJ, Brückner L, Li R, González RC, Schmargon R, Dörr JR, Belk JA, Bafna V, Werner B, Huang W, Henssen AG, Mischel PS, Chang HY. Hung KL, et al. Among authors: mischel ps. bioRxiv [Preprint]. 2023 Jul 19:2023.07.18.549597. doi: 10.1101/2023.07.18.549597. bioRxiv. 2023. Update in: Nature. 2024 Nov;635(8037):201-209. doi: 10.1038/s41586-024-07861-8. PMID: 37503111 Free PMC article. Updated. Preprint.
Breakage fusion bridge cycles drive high oncogene copy number, but not intratumoral genetic heterogeneity or rapid cancer genome change.
Dehkordi SR, Wong IT, Ni J, Luebeck J, Zhu K, Prasad G, Krockenberger L, Xu G, Chowdhury B, Rajkumar U, Caplin A, Muliaditan D, Coruh C, Jin Q, Turner K, Teo SX, Pang AWC, Alexandrov LB, Chua CEL, Furnari FB, Paulson TG, Law JA, Chang HY, Yue F, DasGupta R, Zhao J, Mischel PS, Bafna V. Dehkordi SR, et al. Among authors: mischel ps. bioRxiv [Preprint]. 2023 Dec 13:2023.12.12.571349. doi: 10.1101/2023.12.12.571349. bioRxiv. 2023. Update in: Nat Commun. 2025 Feb 10;16(1):1497. doi: 10.1038/s41467-025-56670-8. PMID: 38168210 Free PMC article. Updated. Preprint.
EcDNA-borne PVT1 fusion stabilizes oncogenic mRNAs.
Yi H, Zhang S, Swinderman J, Wang Y, Kanakaveti V, Hung KL, Wong IT, Srinivasan S, Curtis EJ, Bhargava-Shah A, Li R, Jones MG, Luebeck J, Zhao Y, Belk JA, Kraft K, Shi Q, Yan X, Pritchard SK, Liang FM, Felsher DW, Gilbert LA, Bafna V, Mischel PS, Chang HY. Yi H, et al. Among authors: mischel ps. bioRxiv [Preprint]. 2025 Apr 3:2025.04.01.646515. doi: 10.1101/2025.04.01.646515. bioRxiv. 2025. PMID: 40236070 Free PMC article. Preprint.
245 results