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Page 1
Cis-Regulatory Element and Transcription Factor Circuitry Required for Cell-Type Specific Expression of FOXP3.
Umhoefer JM, Arce MM, Whalen S, Dajani R, Goudy L, Kasinathan S, Belk JA, Zhang W, Zhou R, Subramanya S, Hernandez R, Tran C, Kirthivasan N, Freimer JW, Mowery CT, Nguyen V, Ota M, Gowen BG, Simeonov DR, Curie GL, Li Z, Corn JE, Chang HY, Gilbert LA, Satpathy AT, Pollard KS, Marson A. Umhoefer JM, et al. Among authors: arce mm. bioRxiv [Preprint]. 2025 Jan 14:2024.08.30.610436. doi: 10.1101/2024.08.30.610436. bioRxiv. 2025. PMID: 39282425 Free PMC article. Preprint.
Gene regulatory network inference from CRISPR perturbations in primary CD4+ T cells elucidates the genomic basis of immune disease.
Weinstock JS, Arce MM, Freimer JW, Ota M, Marson A, Battle A, Pritchard JK. Weinstock JS, et al. Among authors: arce mm. bioRxiv [Preprint]. 2023 Oct 24:2023.09.17.557749. doi: 10.1101/2023.09.17.557749. bioRxiv. 2023. Update in: Cell Genom. 2024 Nov 13;4(11):100671. doi: 10.1016/j.xgen.2024.100671. PMID: 37745614 Free PMC article. Updated. Preprint.
Systematic decoding of cis gene regulation defines context-dependent control of the multi-gene costimulatory receptor locus in human T cells.
Mowery CT, Freimer JW, Chen Z, Casaní-Galdón S, Umhoefer JM, Arce MM, Gjoni K, Daniel B, Sandor K, Gowen BG, Nguyen V, Simeonov DR, Garrido CM, Curie GL, Schmidt R, Steinhart Z, Satpathy AT, Pollard KS, Corn JE, Bernstein BE, Ye CJ, Marson A. Mowery CT, et al. Among authors: arce mm. Nat Genet. 2024 Jun;56(6):1156-1167. doi: 10.1038/s41588-024-01743-5. Epub 2024 May 29. Nat Genet. 2024. PMID: 38811842 Free PMC article.
Central control of dynamic gene circuits governs T cell rest and activation.
Arce MM, Umhoefer JM, Arang N, Kasinathan S, Freimer JW, Steinhart Z, Shen H, Pham MTN, Ota M, Wadhera A, Dajani R, Dorovskyi D, Chen YY, Liu Q, Zhou Y, Swaney DL, Obernier K, Shy BR, Carnevale J, Satpathy AT, Krogan NJ, Pritchard JK, Marson A. Arce MM, et al. Nature. 2025 Jan;637(8047):930-939. doi: 10.1038/s41586-024-08314-y. Epub 2024 Dec 11. Nature. 2025. PMID: 39663454 Free PMC article.
CRISPR screens decode cancer cell pathways that trigger γδ T cell detection.
Mamedov MR, Vedova S, Freimer JW, Sahu AD, Ramesh A, Arce MM, Meringa AD, Ota M, Chen PA, Hanspers K, Nguyen VQ, Takeshima KA, Rios AC, Pritchard JK, Kuball J, Sebestyen Z, Adams EJ, Marson A. Mamedov MR, et al. Among authors: arce mm. Nature. 2023 Sep;621(7977):188-195. doi: 10.1038/s41586-023-06482-x. Epub 2023 Aug 30. Nature. 2023. PMID: 37648854 Free PMC article.
The Gastric Cancer Registry: A Genomic Translational Resource for Multidisciplinary Research in Gastric Cancer.
Almeda AF, Grimes SM, Lee H, Greer S, Shin G, McNamara M, Hooker AC, Arce MM, Kubit M, Schauer MC, Van Hummelen P, Ma C, Mills MA, Huang RJ, Hwang JH, Amieva MR, Han SS, Ford JM, Ji HP. Almeda AF, et al. Among authors: arce mm. Cancer Epidemiol Biomarkers Prev. 2022 Sep 2;31(9):1693-1700. doi: 10.1158/1055-9965.EPI-22-0308. Cancer Epidemiol Biomarkers Prev. 2022. PMID: 35771165 Free PMC article.
14 results