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A novel lineage-tracing tool reveals that hypoxic tumor cells drive tumor relapse after radiotherapy.
Menegakis A, Vennin C, Ient J, Groot AJ, Krenning L, Klompmaker R, Friskes A, Ilic M, Yaromina A, Harkes R, van den Broek B, Jakob Sonke J, De Jong M, Piepers J, van Rheenen J, Vooijs MA, Medema RH. Menegakis A, et al. Among authors: groot aj. Radiother Oncol. 2025 Jan;202:110592. doi: 10.1016/j.radonc.2024.110592. Epub 2024 Oct 18. Radiother Oncol. 2025. PMID: 39427933 Free PMC article.
A lineage-tracing tool to map the fate of hypoxic tumour cells.
Vermeer JAF, Ient J, Markelc B, Kaeppler J, Barbeau LMO, Groot AJ, Muschel RJ, Vooijs MA. Vermeer JAF, et al. Among authors: groot aj. Dis Model Mech. 2020 Jul 30;13(7):dmm044768. doi: 10.1242/dmm.044768. Dis Model Mech. 2020. PMID: 32571767 Free PMC article.
The role of Adams in Notch signaling.
Groot AJ, Vooijs MA. Groot AJ, et al. Adv Exp Med Biol. 2012;727:15-36. doi: 10.1007/978-1-4614-0899-4_2. Adv Exp Med Biol. 2012. PMID: 22399336 Free PMC article. Review.
High NOTCH activity induces radiation resistance in non small cell lung cancer.
Theys J, Yahyanejad S, Habets R, Span P, Dubois L, Paesmans K, Kattenbeld B, Cleutjens J, Groot AJ, Schuurbiers OCJ, Lambin P, Bussink J, Vooijs M. Theys J, et al. Among authors: groot aj. Radiother Oncol. 2013 Sep;108(3):440-445. doi: 10.1016/j.radonc.2013.06.020. Epub 2013 Jul 25. Radiother Oncol. 2013. PMID: 23891097 Free PMC article.
Conditional inactivation of HIF-1 using intrabodies.
Groot AJ, Gort EH, van der Wall E, van Diest PJ, Vooijs M. Groot AJ, et al. Cell Oncol. 2008;30(5):397-409. doi: 10.3233/clo-2008-0442. Cell Oncol. 2008. PMID: 18791271 Free PMC article.
88 results