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144 results

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Exploring machine learning tools in a retrospective case-study of patients with metastatic non-small cell lung cancer treated with first-line immunotherapy: A feasibility single-centre experience.
Ogliari FR, Traverso A, Barbieri S, Montagna M, Chiabrando F, Versino E, Bosco A, Lin A, Ferrara R, Oresti S, Damiano G, Viganò MG, Ferrara M, Riva ST, Nuccio A, Venanzi FM, Vignale D, Cicala G, Palmisano A, Cascinu S, Gregorc V, Bulotta A, Esposito A, Tacchetti C, Reni M. Ogliari FR, et al. Among authors: tacchetti c. Lung Cancer. 2025 Jan;199:108075. doi: 10.1016/j.lungcan.2024.108075. Epub 2024 Dec 31. Lung Cancer. 2025. PMID: 39752796
Molecularly Distinct Clathrin-Coated Pits Differentially Impact EGFR Fate and Signaling.
Pascolutti R, Algisi V, Conte A, Raimondi A, Pasham M, Upadhyayula S, Gaudin R, Maritzen T, Barbieri E, Caldieri G, Tordonato C, Confalonieri S, Freddi S, Malabarba MG, Maspero E, Polo S, Tacchetti C, Haucke V, Kirchhausen T, Di Fiore PP, Sigismund S. Pascolutti R, et al. Among authors: tacchetti c. Cell Rep. 2024 Nov 26;43(11):114970. doi: 10.1016/j.celrep.2024.114970. Epub 2024 Oct 30. Cell Rep. 2024. PMID: 39480812 Free PMC article. No abstract available.
An intrinsic mechanism of metabolic tuning promotes cardiac resilience to stress.
Sorge M, Savoré G, Gallo A, Acquarone D, Sbroggiò M, Velasco S, Zamporlini F, Femminò S, Moiso E, Morciano G, Balmas E, Raimondi A, Nattenberg G, Stefania R, Tacchetti C, Rizzo AM, Corsetto P, Ghigo A, Turco E, Altruda F, Silengo L, Pinton P, Raffaelli N, Sniadecki NJ, Penna C, Pagliaro P, Hirsch E, Riganti C, Tarone G, Bertero A, Brancaccio M. Sorge M, et al. Among authors: tacchetti c. EMBO Mol Med. 2024 Oct;16(10):2450-2484. doi: 10.1038/s44321-024-00132-z. Epub 2024 Sep 13. EMBO Mol Med. 2024. PMID: 39271959 Free PMC article.
A tripartite organelle platform links growth factor receptor signaling to mitochondrial metabolism.
Mesa D, Barbieri E, Raimondi A, Freddi S, Miloro G, Jendrisek G, Caldieri G, Quarto M, Schiano Lomoriello I, Malabarba MG, Bresci A, Manetti F, Vernuccio F, Abdo H, Scita G, Lanzetti L, Polli D, Tacchetti C, Pinton P, Bonora M, Di Fiore PP, Sigismund S. Mesa D, et al. Among authors: tacchetti c. Nat Commun. 2024 Jun 15;15(1):5119. doi: 10.1038/s41467-024-49543-z. Nat Commun. 2024. PMID: 38879572 Free PMC article.
PML restrains p53 activity and cellular senescence in clear cell renal cell carcinoma.
Simoni M, Menegazzi C, Fracassi C, Biffi CC, Genova F, Tenace NP, Lucianò R, Raimondi A, Tacchetti C, Brugarolas J, Mazza D, Bernardi R. Simoni M, et al. Among authors: tacchetti c. EMBO Mol Med. 2024 Jun;16(6):1324-1351. doi: 10.1038/s44321-024-00077-3. Epub 2024 May 10. EMBO Mol Med. 2024. PMID: 38730056 Free PMC article.
Chromatin organization drives the search mechanism of nuclear factors.
Mazzocca M, Loffreda A, Colombo E, Fillot T, Gnani D, Falletta P, Monteleone E, Capozi S, Bertrand E, Legube G, Lavagnino Z, Tacchetti C, Mazza D. Mazzocca M, et al. Among authors: tacchetti c. Nat Commun. 2023 Oct 13;14(1):6433. doi: 10.1038/s41467-023-42133-5. Nat Commun. 2023. PMID: 37833263 Free PMC article.
AI-SCoRE (artificial intelligence-SARS CoV2 risk evaluation): a fast, objective and fully automated platform to predict the outcome in COVID-19 patients.
Palmisano A, Vignale D, Boccia E, Nonis A, Gnasso C, Leone R, Montagna M, Nicoletti V, Bianchi AG, Brusamolino S, Dorizza A, Moraschini M, Veettil R, Cereda A, Toselli M, Giannini F, Loffi M, Patelli G, Monello A, Iannopollo G, Ippolito D, Mancini EM, Pontone G, Vignali L, Scarnecchia E, Iannacone M, Baffoni L, Sperandio M, de Carlini CC, Sironi S, Rapezzi C, Antiga L, Jagher V, Di Serio C, Furlanello C, Tacchetti C, Esposito A. Palmisano A, et al. Among authors: tacchetti c. Radiol Med. 2022 Sep;127(9):960-972. doi: 10.1007/s11547-022-01518-0. Epub 2022 Aug 29. Radiol Med. 2022. PMID: 36038790 Free PMC article.
Pathological mitophagy disrupts mitochondrial homeostasis in Leber's hereditary optic neuropathy.
Danese A, Patergnani S, Maresca A, Peron C, Raimondi A, Caporali L, Marchi S, La Morgia C, Del Dotto V, Zanna C, Iannielli A, Segnali A, Di Meo I, Cavaliere A, Lebiedzinska-Arciszewska M, Wieckowski MR, Martinuzzi A, Moraes-Filho MN, Salomao SR, Berezovsky A, Belfort R Jr, Buser C, Ross-Cisneros FN, Sadun AA, Tacchetti C, Broccoli V, Giorgi C, Tiranti V, Carelli V, Pinton P. Danese A, et al. Among authors: tacchetti c. Cell Rep. 2022 Jul 19;40(3):111124. doi: 10.1016/j.celrep.2022.111124. Cell Rep. 2022. PMID: 35858578 Free PMC article.
144 results