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Page 1
Rapid in silico directed evolution by a protein language model with EVOLVEpro.
Jiang K, Yan Z, Di Bernardo M, Sgrizzi SR, Villiger L, Kayabolen A, Kim BJ, Carscadden JK, Hiraizumi M, Nishimasu H, Gootenberg JS, Abudayyeh OO. Jiang K, et al. Among authors: sgrizzi sr. Science. 2025 Jan 24;387(6732):eadr6006. doi: 10.1126/science.adr6006. Epub 2025 Jan 24. Science. 2025. PMID: 39571002
Rapid protein evolution by few-shot learning with a protein language model.
Jiang K, Yan Z, Di Bernardo M, Sgrizzi SR, Villiger L, Kayabolen A, Kim B, Carscadden JK, Hiraizumi M, Nishimasu H, Gootenberg JS, Abudayyeh OO. Jiang K, et al. Among authors: sgrizzi sr. bioRxiv [Preprint]. 2024 Jul 18:2024.07.17.604015. doi: 10.1101/2024.07.17.604015. bioRxiv. 2024. PMID: 39071429 Free PMC article. Preprint.
Programmable eukaryotic protein synthesis with RNA sensors by harnessing ADAR.
Jiang K, Koob J, Chen XD, Krajeski RN, Zhang Y, Volf V, Zhou W, Sgrizzi SR, Villiger L, Gootenberg JS, Chen F, Abudayyeh OO. Jiang K, et al. Among authors: sgrizzi sr. Nat Biotechnol. 2023 May;41(5):698-707. doi: 10.1038/s41587-022-01534-5. Epub 2022 Oct 27. Nat Biotechnol. 2023. PMID: 36302988