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Artificial intelligence-based rapid brain volumetry substantially improves differential diagnosis in dementia.
Rudolph J, Rueckel J, Döpfert J, Ling WX, Opalka J, Brem C, Hesse N, Ingenerf M, Koliogiannis V, Solyanik O, Hoppe BF, Zimmermann H, Flatz W, Forbrig R, Patzig M, Rauchmann BS, Perneczky R, Peters O, Priller J, Schneider A, Fliessbach K, Hermann A, Wiltfang J, Jessen F, Düzel E, Buerger K, Teipel S, Laske C, Synofzik M, Spottke A, Ewers M, Dechent P, Haynes JD, Levin J, Liebig T, Ricke J, Ingrisch M, Stoecklein S. Rudolph J, et al. Among authors: synofzik m. Alzheimers Dement (Amst). 2024 Dec 11;16(4):e70037. doi: 10.1002/dad2.70037. eCollection 2024 Oct-Dec. Alzheimers Dement (Amst). 2024. PMID: 39665087 Free PMC article.
Multiclass prediction of different dementia syndromes based on multi-centric volumetric MRI imaging.
Lampe L, Huppertz HJ, Anderl-Straub S, Albrecht F, Ballarini T, Bisenius S, Mueller K, Niehaus S, Fassbender K, Fliessbach K, Jahn H, Kornhuber J, Lauer M, Prudlo J, Schneider A, Synofzik M, Kassubek J, Danek A, Villringer A, Diehl-Schmid J, Otto M, Schroeter ML; FTLD Consortium Germany. Lampe L, et al. Among authors: synofzik m. Neuroimage Clin. 2023;37:103320. doi: 10.1016/j.nicl.2023.103320. Epub 2023 Jan 5. Neuroimage Clin. 2023. PMID: 36623349 Free PMC article.
Resting-state alterations in behavioral variant frontotemporal dementia are related to the distribution of monoamine and GABA neurotransmitter systems.
Hahn L, Eickhoff SB, Mueller K, Schilbach L, Barthel H, Fassbender K, Fliessbach K, Kornhuber J, Prudlo J, Synofzik M, Wiltfang J, Diehl-Schmid J; FTLD Consortium; Otto M, Dukart J, Schroeter ML. Hahn L, et al. Among authors: synofzik m. Elife. 2024 Jan 15;13:e86085. doi: 10.7554/eLife.86085. Elife. 2024. PMID: 38224473 Free PMC article.
Extending the phenotypic spectrum assessed by the CDR plus NACC FTLD in genetic frontotemporal dementia.
Samra K, Peakman G, MacDougall AM, Bouzigues A, Greaves CV, Convery RS, van Swieten JC, Jiskoot L, Seelaar H, Moreno F, Sanchez-Valle R, Laforce R, Graff C, Masellis M, Tartaglia MC, Rowe JB, Borroni B, Finger E, Synofzik M, Galimberti D, Vandenberghe R, de Mendonça A, Butler CR, Gerhard A, Ducharme S, Ber IL, Tiraboschi P, Santana I, Pasquier F, Levin J, Otto M, Sorbi S, Rohrer JD, Russell LL;  Genetic FTD Initiative (GENFI). Samra K, et al. Among authors: synofzik m. Alzheimers Dement (Amst). 2024 Apr 14;16(2):e12571. doi: 10.1002/dad2.12571. eCollection 2024 Apr-Jun. Alzheimers Dement (Amst). 2024. PMID: 38623386 Free PMC article.
Neurofilaments and progranulin are related to atrophy in frontotemporal lobar degeneration - A transdiagnostic study cross-validating atrophy and fluid biomarkers.
Hüper L, Steinacker P, Polyakova M, Mueller K, Godulla J, Herzig S, Danek A, Engel A, Diehl-Schmid J, Classen J, Fassbender K, Fliessbach K, Jahn H, Kassubek J, Kornhuber J, Landwehrmeyer B, Lauer M, Obrig H, Oeckl P, Prudlo J, Saur D, Anderl-Straub S, Synofzik M, Wagner M, Wiltfang J, Winkelmann J, Volk AE; FTLD Consortium Germany; Huppertz HJ, Otto M, Schroeter ML. Hüper L, et al. Among authors: synofzik m. Alzheimers Dement. 2024 Jul;20(7):4461-4475. doi: 10.1002/alz.13863. Epub 2024 Jun 12. Alzheimers Dement. 2024. PMID: 38865340 Free PMC article.
Frontoparietal network integrity supports cognitive function in pre-symptomatic frontotemporal dementia: Multimodal analysis of brain function, structure, and perfusion.
Liu X, Jones PS, Pasternak M, Masellis M, Bouzigues A, Russell LL, Foster PH, Ferry-Bolder E, van Swieten J, Jiskoot L, Seelaar H, Sanchez-Valle R, Laforce R, Graff C, Galimberti D, Vandenberghe R, de Mendonça A, Tiraboschi P, Santana I, Gerhard A, Levin J, Sorbi S, Otto M, Pasquier F, Ducharme S, Butler C, Le Ber I, Finger E, Tartaglia MC, Synofzik M, Moreno F, Borroni B, Rohrer JD, Tsvetanov KA, Rowe JB; GENFI consortium. Liu X, et al. Among authors: synofzik m. Alzheimers Dement. 2024 Dec;20(12):8576-8594. doi: 10.1002/alz.14299. Epub 2024 Oct 17. Alzheimers Dement. 2024. PMID: 39417382 Free PMC article.
Dissecting neural correlates of theory of mind and executive functions in behavioral variant frontotemporal dementia.
Weise CM, Engel A, Polyakova M, Wu Q, Mueller K, Herzig S, Jech R, Diehl-Schmid J, Riedl L, Anderl-Straub S, Kornhuber J, Fassbender K, Wiltfang J, Fliessbach K, Prudlo J, Synofzik M, Danek A, Otto M, Schroeter ML; FTLD Consortium Germany. Weise CM, et al. Among authors: synofzik m. Alzheimers Res Ther. 2024 Oct 26;16(1):237. doi: 10.1186/s13195-024-01596-4. Alzheimers Res Ther. 2024. PMID: 39462381 Free PMC article.
"The DESCRIBE-ALS-FTD study: a prospective multicenter observational study of the ALS-FTD spectrum".
Hermann A, Prudlo J, Kasper E, Synofzik M, Peters O, Priller J, Dinter E, Wiltfang J, Zerr I, Flöel A, Bürger K, Höglinger GU, Levin J, Düzel E, Teipel S, Beichert L, Brosseron F, Wagner M, Frommann I, Ramirez A, Yakupov R, Schmid M, Lingor P, Haass C; DESCRIBE-ALS and DESCRIBE-FTD consortium; Spottke A, Günther R, Weydt P, Neumann M, Schneider A. Hermann A, et al. Among authors: synofzik m. Amyotroph Lateral Scler Frontotemporal Degener. 2025 Jun 9:1-9. doi: 10.1080/21678421.2025.2509617. Online ahead of print. Amyotroph Lateral Scler Frontotemporal Degener. 2025. PMID: 40488385 Free article.
522 results