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Alzheimer's disease-associated CD83(+) microglia are linked with increased immunoglobulin G4 and human cytomegalovirus in the gut, vagal nerve, and brain.
Readhead BP, Mastroeni DF, Wang Q, Sierra MA, de Ávila C, Jimoh TO, Haure-Mirande JV, Atanasoff KE, Nolz J, Suazo C, Barton NJ, Orszulak AR, Chigas SM, Tran K, Mirza A, Ryon K, Proszynski J, Najjar D, Dudley JT, Liu STH, Gandy S, Ehrlich ME, Alsop E, Antone J, Reiman R, Funk C, Best RL, Jhatro M, Kamath K, Shon J, Kowalik TF, Bennett DA, Liang WS, Serrano GE, Beach TG, Van Keuren-Jensen K, Mason CE, Chan Y, Lim ET, Tortorella D, Reiman EM. Readhead BP, et al. Among authors: gandy s. Alzheimers Dement. 2025 Jan;21(1):e14401. doi: 10.1002/alz.14401. Epub 2024 Dec 19. Alzheimers Dement. 2025. PMID: 39698934 Free PMC article.
BCI-838, an orally active mGluR2/3 receptor antagonist pro-drug, rescues learning behavior deficits in the PS19 MAPTP301S mouse model of tauopathy.
Perez-Garcia G, Bicak M, Haure-Mirande JV, Perez GM, Otero-Pagan A, Gama Sosa MA, De Gasperi R, Sano M, Barlow C, Gage FH, Readhead B, Ehrlich ME, Gandy S, Elder GA. Perez-Garcia G, et al. Among authors: gandy s. Neurosci Lett. 2023 Feb 16;797:137080. doi: 10.1016/j.neulet.2023.137080. Epub 2023 Jan 16. Neurosci Lett. 2023. PMID: 36657633 Free PMC article.
Plasma amyloid beta 40/42, phosphorylated tau 181, and neurofilament light are associated with cognitive impairment and neuropathological changes among World Trade Center responders: A prospective cohort study of exposures and cognitive aging at midlife.
Kritikos M, Diminich ED, Meliker J, Mielke M, Bennett DA, Finch CE, Gandy SE, Carr MA, Yang X, Kotov R, Kuan PF, Bromet EJ, Clouston SAP, Luft BJ. Kritikos M, et al. Alzheimers Dement (Amst). 2023 Mar 8;15(1):e12409. doi: 10.1002/dad2.12409. eCollection 2023 Jan-Mar. Alzheimers Dement (Amst). 2023. PMID: 36911360 Free PMC article.
Genetic architecture of plasma Alzheimer disease biomarkers.
Bradley J, Gorijala P, Schindler SE, Sung YJ, Ances B; Alzheimer’s Disease Neuroimaging Initiative, the Human Connectome Project; Fernandez MV, Cruchaga C. Bradley J, et al. Hum Mol Genet. 2023 Jul 20;32(15):2532-2543. doi: 10.1093/hmg/ddad087. Hum Mol Genet. 2023. PMID: 37208024 Free PMC article.
Beneficial effects of physical exercise and an orally active mGluR2/3 antagonist pro-drug on neurogenesis and behavior in an Alzheimer's amyloidosis model.
Perez Garcia G, Bicak M, Buros J, Haure-Mirande JV, Perez GM, Otero-Pagan A, Gama Sosa MA, De Gasperi R, Sano M, Gage FH, Barlow C, Dudley JT, Glicksberg BS, Wang Y, Readhead B, Ehrlich ME, Elder GA, Gandy S. Perez Garcia G, et al. Among authors: gandy s. Front Dement. 2023 Sep 6;2:1198006. doi: 10.3389/frdem.2023.1198006. eCollection 2023. Front Dement. 2023. PMID: 39081972 Free PMC article.
461 results