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Novel Immune Response Evasion Strategy to Redose Adeno-associated Viral Vectors and Prolong Survival in Surfactant Protein-B-Deficient Mice.
Kang MH, Thomas SP, Westley C, Blouin T, Xu L, Chan YK, Lisk E, Allen SE, Vadivel A, Nangle K, Ramamurthy J, Pei Y, Lewis LA, Chiang JJ, Romeo MJ, Vaena S, O'Quinn EC, Schrecker HD, Langdon CG, Nietert PJ, Church GM, Whitsett JA, Wootton SK, Thébaud B. Kang MH, et al. Among authors: vadivel a. Am J Respir Cell Mol Biol. 2025 Jul;73(1):120-134. doi: 10.1165/rcmb.2024-0247OC. Am J Respir Cell Mol Biol. 2025. PMID: 39805087
A lung tropic AAV vector improves survival in a mouse model of surfactant B deficiency.
Kang MH, van Lieshout LP, Xu L, Domm JM, Vadivel A, Renesme L, Mühlfeld C, Hurskainen M, Mižíková I, Pei Y, van Vloten JP, Thomas SP, Milazzo C, Cyr-Depauw C, Whitsett JA, Nogee LM, Wootton SK, Thébaud B. Kang MH, et al. Among authors: vadivel a. Nat Commun. 2020 Aug 6;11(1):3929. doi: 10.1038/s41467-020-17577-8. Nat Commun. 2020. PMID: 32764559 Free PMC article.
A promoterless AAV6.2FF-based lung gene editing platform for the correction of surfactant protein B deficiency.
Thomas SP, Domm JM, van Vloten JP, Xu L, Vadivel A, Yates JGE, Pei Y, Ingrao J, van Lieshout LP, Jackson SR, Minott JA, Achuthan A, Mehrani Y, McAusland TM, Zhang W, Karimi K, Vaughan AE, de Jong J, Kang MH, Thebaud B, Wootton SK. Thomas SP, et al. Among authors: vadivel a. Mol Ther. 2023 Dec 6;31(12):3457-3477. doi: 10.1016/j.ymthe.2023.10.002. Epub 2023 Oct 7. Mol Ther. 2023. PMID: 37805711 Free PMC article.
47 results