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Page 1
A novel dominant-negative variant of IRF8 in a mother and son: Clinical, phenotypic and biological characteristics.
Ham H, Isham CR, Ristagno EH, Correia C, Ennis SM, Kandasamy RK, Garapati K, Zhang C, Kohlhagen MC, Sadighi Akha E, Rodriguez-Quevedo MF, Schultz DF, Chen B, Boyce TG, Gregory SW, Kohorst MA, Dasari S, Murray DL, Halling KC, Kipp BR, Kumánovics A, Li H, Pandey A, Billadeau DD, Sadighi Akha AA. Ham H, et al. Among authors: schultz df. J Allergy Clin Immunol. 2025 Jun;155(6):2022-2037. doi: 10.1016/j.jaci.2024.11.041. Epub 2025 Mar 11. J Allergy Clin Immunol. 2025. PMID: 40072380
Lysosomal NKG7 restrains mTORC1 activity to promote CD8+ T cell durability and tumor control.
Ham H, Hirdler JB, Bihnam DT, Mao Z, Gicobi JK, Macedo BG, Rodriguez-Quevedo MF, Schultz DF, Correia C, Zhong J, Martinez KE, Banuelos A, Ashton DS, Lagnado AB, Guo R, Pessoa R, Pandey A, Li H, Lucien F, Borges da Silva H, Dong H, Billadeau DD. Ham H, et al. Among authors: schultz df. Nat Commun. 2025 Feb 14;16(1):1628. doi: 10.1038/s41467-025-56931-6. Nat Commun. 2025. PMID: 39952956 Free PMC article.
Loss of HD-PTP function results in lipodystrophy, defective cellular signaling and altered lipid homeostasis.
Schultz DF, Davies BA, Payne JA, Martin CP, Minard AY, Childs BG, Zhang C, Jeganathan KB, Sturmlechner I, White TA, de Bruin A, Harkema L, Chen H, Davies MA, Jachim S, LeBrasseur NK, Piper RC, Li H, Baker DJ, van Deursen J, Billadeau DD, Katzmann DJ. Schultz DF, et al. J Cell Sci. 2024 Sep 15;137(18):jcs262032. doi: 10.1242/jcs.262032. Epub 2024 Sep 27. J Cell Sci. 2024. PMID: 39155850